Genetic enhancement, Immunology, Severe combined immunodeficiency, Molecular biology and Cell biology are her primary areas of study. Her Genetic enhancement research integrates issues from Insertional mutagenesis, Vector, Viral vector and In vivo. Her Immunology research includes elements of HAX1 and G6PC3.
Her Severe combined immunodeficiency research is multidisciplinary, incorporating perspectives in Progenitor cell, Stem cell, Natural killer cell and Transplantation. Christine Kinnon combines subjects such as Gene expression, Gene, Receptor tyrosine kinase and Bruton's tyrosine kinase with her study of Molecular biology. As a part of the same scientific study, Christine Kinnon usually deals with the Gene, concentrating on Kinase and frequently concerns with Locus and X-linked agammaglobulinemia.
Christine Kinnon spends much of her time researching Immunology, Genetic enhancement, Genetics, Molecular biology and Gene. Her Immunology research incorporates elements of Mutation, Severe combined immunodeficiency and Transplantation. Her study in Severe combined immunodeficiency is interdisciplinary in nature, drawing from both Progenitor cell and Natural killer cell.
Her studies deal with areas such as Cancer research, Viral vector, Transgene and Virology as well as Genetic enhancement. Her Virology study combines topics in areas such as Cytotoxic T cell, Haematopoiesis, Adeno-associated virus and Disease. Her studies in Molecular biology integrate themes in fields like IL-2 receptor, Chronic granulomatous disease, Transfection, B cell and Reporter gene.
Her scientific interests lie mostly in Genetic enhancement, Immunology, World Wide Web, Severe combined immunodeficiency and Cell biology. The various areas that she examines in her Genetic enhancement study include Cancer research, Clinical trial, Bioinformatics, Viral vector and Hematopoietic stem cell. Her research integrates issues of Molecular biology, Transgene and In vivo in her study of Viral vector.
Her Immunology study combines topics from a wide range of disciplines, such as Progenitor cell, Haematopoiesis, Stem cell and Transplantation. Her study in Severe combined immunodeficiency focuses on X-linked severe combined immunodeficiency in particular. Her work in Cellular immunity addresses issues such as Virology, which are connected to fields such as Gene.
Her primary areas of investigation include Genetic enhancement, Immunology, Severe combined immunodeficiency, Molecular biology and Viral vector. Her Genetic enhancement research includes themes of Cancer research, In vivo and Virology. The study incorporates disciplines such as Cytotoxic T cell and Hematopoietic stem cell in addition to Immunology.
Her Severe combined immunodeficiency study integrates concerns from other disciplines, such as Progenitor cell and Transplantation. Her biological study spans a wide range of topics, including Gene expression, Transduction, Cell biology, Spindle midzone and Arp2/3 complex. Regulation of gene expression, Reporter gene, Myeloid and CAAT box is closely connected to Transgene in her research, which is encompassed under the umbrella topic of Viral vector.
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The gene involved in X-linked agammaglobulinaemia is a member of the src family of protein-tyrosine kinases
Vetrie D;Vorechovský I;Sideras P;Sideras P;Holland J.
Insertional mutagenesis combined with acquired somatic mutations causes leukemogenesis following gene therapy of SCID-X1 patients
Steven J. Howe;Marc R. Mansour;Kerstin Schwarzwaelder;Cynthia Bartholomae.
Journal of Clinical Investigation (2008)
Gene therapy of X-linked severe combined immunodeficiency by use of a pseudotyped gammaretroviral vector
H Bobby Gaspar;Kathryn L Parsley;Steven Howe;Doug King.
The Lancet (2004)
High-level transduction and gene expression in hematopoietic repopulating cells using a human imunodeficiency virus type 1-based lentiviral vector containing an internal spleen focus forming virus promoter
Christophe Demaison;Kathryn Parsley;Gaby Brouns;Michaela Scherr.
Human Gene Therapy (2002)
Effective gene therapy with nonintegrating lentiviral vectors
Rafael J Yáñez-Muñoz;Rafael J Yáñez-Muñoz;Rafael J Yáñez-Muñoz;Kamaljit S Balaggan;Angus MacNeil;Steven J Howe.
Nature Medicine (2006)
Restoration of photoreceptor ultrastructure and function in retinal degeneration slow mice by gene therapy
Robin R. Ali;Gian-Marco Sarra;Clare Stephens;Mahesh de Alwis.
Nature Genetics (2000)
Hematopoietic Stem Cell Gene Therapy for Adenosine Deaminase–Deficient Severe Combined Immunodeficiency Leads to Long-Term Immunological Recovery and Metabolic Correction
H. Bobby Gaspar;H. Bobby Gaspar;Samantha Cooray;Samantha Cooray;Kimberly C. Gilmour;Kimberly C. Gilmour;Kathryn L. Parsley;Kathryn L. Parsley.
Science Translational Medicine (2011)
Enhanced human cell engraftment in mice deficient in RAG2 and the common cytokine receptor gamma chain
J P Goldman;M P Blundell;L Lopes;C Kinnon.
British Journal of Haematology (1998)
Gene Transfer into the Mouse Retina Mediated by an Adeno-Associated Viral Vector
Robin R. Ali;Martin B. Reichel;Adrian J. Thrasher;Roland J. Levinsky.
Human Molecular Genetics (1996)
Successful reconstitution of immunity in ADA-SCID by stem cell gene therapy following cessation of PEG-ADA and use of mild preconditioning.
H. Bobby Gaspar;H. Bobby Gaspar;Emma Bjorkegren;Kate Parsley;Kate Parsley;Kimberly C. Gilmour;Kimberly C. Gilmour.
Molecular Therapy (2006)
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