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C. I. Edvard Smith

D-Index & Metrics

Biology and Biochemistry

D-Index
65
Citations
17032
World Ranking
9071
National Ranking
122

C. I. Edvard Smith publication distribution in Biology and Biochemistry in 2026

The chart shows the distribution of publications by all Research.com ranked scientists in the field of Biology and Biochemistry in 2026. The highlighted bar marks where C. I. Edvard Smith sits on this spectrum.

47–56 publications: 8 scientists 57–66 publications: 35 scientists 67–76 publications: 106 scientists 77–86 publications: 231 scientists 87–96 publications: 413 scientists 97–106 publications: 546 scientists 107–116 publications: 704 scientists 117–126 publications: 848 scientists 127–136 publications: 980 scientists 137–146 publications: 942 scientists 147–156 publications: 969 scientists 157–166 publications: 949 scientists 167–176 publications: 951 scientists 177–186 publications: 915 scientists 187–196 publications: 787 scientists 197–206 publications: 840 scientists 207–216 publications: 733 scientists 217–226 publications: 708 scientists 227–236 publications: 651 scientists 237–246 publications: 605 scientists 247–256 publications: 510 scientists 257–266 publications: 524 scientists 267–276 publications: 434 scientists 277–286 publications: 417 scientists 287–296 publications: 350 scientists 297–306 publications: 363 scientists 307–316 publications: 315 scientists 317–326 publications: 296 scientists 327–336 publications: 261 scientists 337–346 publications: 240 scientists 347–356 publications: 219 scientists 357–366 publications: 196 scientists 367–376 publications: 154 scientists 377–386 publications: 161 scientists 387–396 publications: 155 scientists 397–406 publications: 145 scientists 407–416 publications: 124 scientists 417–426 publications: 112 scientists 427–436 publications: 132 scientists 437–446 publications: 116 scientists 447–456 publications: 99 scientists 457–466 publications: 81 scientists 467–476 publications: 91 scientists 477–486 publications: 80 scientists 487–496 publications: 80 scientists 497–506 publications: 59 scientists 507–516 publications: 36 scientists 517–526 publications: 46 scientists 527–536 publications: 54 scientists 537–546 publications: 44 scientists 547–556 publications: 43 scientists 557–566 publications: 43 scientists 567–576 publications: 42 scientists 577–586 publications: 25 scientists 587–596 publications: 34 scientists 597–606 publications: 23 scientists 607–616 publications: 33 scientists 617–626 publications: 31 scientists 627–636 publications: 27 scientists 637–646 publications: 25 scientists 647–656 publications: 28 scientists 657–666 publications: 34 scientists 667–676 publications: 18 scientists 677–686 publications: 16 scientists 687–696 publications: 10 scientists 697–706 publications: 12 scientists 707–716 publications: 21 scientists 717–726 publications: 12 scientists 727–736 publications: 12 scientists 737–746 publications: 10 scientists 747–756 publications: 7 scientists 757–766 publications: 13 scientists 767–776 publications: 15 scientists 777–786 publications: 13 scientists 787–796 publications: 9 scientists 797–806 publications: 9 scientists 807–816 publications: 7 scientists 817–826 publications: 4 scientists 827–836 publications: 9 scientists 837–846 publications: 7 scientists 847–856 publications: 3 scientists 857–866 publications: 5 scientists 867–876 publications: 5 scientists 877–886 publications: 11 scientists 887–896 publications: 3 scientists 897–906 publications: 4 scientists 907–916 publications: 7 scientists 917–926 publications: 5 scientists 927–936 publications: 6 scientists 937–946 publications: 6 scientists 947–956 publications: 3 scientists 957–966 publications: 7 scientists 967–976 publications: 2 scientists 977–986 publications: 2 scientists 987–996 publications: 1 scientists 997–1,006 publications: 5 scientists 1,007–1,016 publications: 2 scientists 1,017–1,026 publications: 2 scientists 1,027 publications: 1 scientists 1,028+ publications: 100 scientists
47 publications 1,028+

This scientist: 269 publications — 72nd percentile

72% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 1,028 publications or more.

C. I. Edvard Smith D-index placement in Biology and Biochemistry in 2026

The chart shows the D-index (discipline H-index) distribution of Biology and Biochemistry scientists ranked by Research.com in 2026. The highlighted bar marks where C. I. Edvard Smith sits on this spectrum.

40–41 D-Index: 80 scientists 42–43 D-Index: 183 scientists 44–45 D-Index: 316 scientists 46–47 D-Index: 504 scientists 48–49 D-Index: 718 scientists 50–51 D-Index: 899 scientists 52–53 D-Index: 1,025 scientists 54–55 D-Index: 1,149 scientists 56–57 D-Index: 1,235 scientists 58–59 D-Index: 1,253 scientists 60–61 D-Index: 1,162 scientists 62–63 D-Index: 1,130 scientists 64–65 D-Index: 1,031 scientists 66–67 D-Index: 897 scientists 68–69 D-Index: 814 scientists 70–71 D-Index: 714 scientists 72–73 D-Index: 709 scientists 74–75 D-Index: 596 scientists 76–77 D-Index: 512 scientists 78–79 D-Index: 473 scientists 80–81 D-Index: 412 scientists 82–83 D-Index: 373 scientists 84–85 D-Index: 358 scientists 86–87 D-Index: 285 scientists 88–89 D-Index: 273 scientists 90–91 D-Index: 227 scientists 92–93 D-Index: 208 scientists 94–95 D-Index: 193 scientists 96–97 D-Index: 153 scientists 98–99 D-Index: 157 scientists 100–101 D-Index: 148 scientists 102–103 D-Index: 120 scientists 104–105 D-Index: 113 scientists 106–107 D-Index: 100 scientists 108–109 D-Index: 86 scientists 110–111 D-Index: 67 scientists 112–113 D-Index: 71 scientists 114–115 D-Index: 73 scientists 116–117 D-Index: 64 scientists 118–119 D-Index: 53 scientists 120–121 D-Index: 60 scientists 122–123 D-Index: 54 scientists 124–125 D-Index: 43 scientists 126–127 D-Index: 38 scientists 128–129 D-Index: 49 scientists 130–131 D-Index: 26 scientists 132–133 D-Index: 18 scientists 134–135 D-Index: 23 scientists 136–137 D-Index: 32 scientists 138–139 D-Index: 32 scientists 140–141 D-Index: 27 scientists 142–143 D-Index: 19 scientists 144–145 D-Index: 22 scientists 146–147 D-Index: 12 scientists 148–149 D-Index: 16 scientists 150–151 D-Index: 14 scientists 152–153 D-Index: 10 scientists 154–155 D-Index: 13 scientists 156–157 D-Index: 10 scientists 158–159 D-Index: 7 scientists 160–161 D-Index: 9 scientists 162–163 D-Index: 13 scientists 164–165 D-Index: 4 scientists 166 D-Index: 4 scientists 167+ D-Index: 98 scientists
40 D-Index 167+

This scientist: 65 D-Index — 55th percentile

55% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 167 D-Index or more.

Overview

What is he best known for?

The fields of study he is best known for:

  • Gene
  • DNA
  • Enzyme

His primary areas of investigation include Cell biology, Bruton's tyrosine kinase, Molecular biology, Antibody and Immunology. His Cell biology research incorporates elements of Microvesicles, Biochemistry, Transfection and In vivo. His work deals with themes such as Kinase and Gene, which intersect with Bruton's tyrosine kinase.

The concepts of his Molecular biology study are interwoven with issues in Alpha, In vitro, Immunoglobulin A, Gene silencing and Transforming growth factor beta. His biological study spans a wide range of topics, including Spleen, Messenger RNA and Pokeweed mitogen. His study in Immunology is interdisciplinary in nature, drawing from both Genetic inheritance and Gene deletion.

His most cited work include:

  • The gene involved in X-linked agammaglobulinaemia is a member of the src family of protein-tyrosine kinases (1181 citations)
  • Extracellular vesicle in vivo biodistribution is determined by cell source, route of administration and targeting (510 citations)
  • Cells release subpopulations of exosomes with distinct molecular and biological properties (425 citations)

What are the main themes of his work throughout his whole career to date?

His scientific interests lie mostly in Molecular biology, Bruton's tyrosine kinase, Genetics, Immunology and Antibody. He has researched Molecular biology in several fields, including Gene expression, Virology, Oligonucleotide, DNA and Polyclonal antibodies. His Bruton's tyrosine kinase research is multidisciplinary, incorporating elements of Cancer research and Kinase.

His research links Antigen with Antibody. He interconnects Pleckstrin homology domain and Proto-oncogene tyrosine-protein kinase Src in the investigation of issues within Tyrosine kinase. His studies link Biochemistry with Cell biology.

He most often published in these fields:

  • Molecular biology (31.80%)
  • Bruton's tyrosine kinase (23.37%)
  • Genetics (20.69%)

What were the highlights of his more recent work (between 2012-2021)?

  • Oligonucleotide (13.79%)
  • Cell biology (14.94%)
  • Bruton's tyrosine kinase (23.37%)

In recent papers he was focusing on the following fields of study:

His primary areas of study are Oligonucleotide, Cell biology, Bruton's tyrosine kinase, Genetics and Biochemistry. C. I. Edvard Smith combines subjects such as Biophysics, Nucleic acid and Transfection with his study of Oligonucleotide. His Cell biology research integrates issues from Gene expression and Dystrophin.

His Bruton's tyrosine kinase research is included under the broader classification of Tyrosine kinase. His Genetics research focuses on Disease and how it connects with Gene targeting and B cell. His work is dedicated to discovering how Locked nucleic acid, Electrophoretic mobility shift assay are connected with Molecular biology and other disciplines.

Between 2012 and 2021, his most popular works were:

  • Extracellular vesicle in vivo biodistribution is determined by cell source, route of administration and targeting (510 citations)
  • Cells release subpopulations of exosomes with distinct molecular and biological properties (425 citations)
  • Ultrafiltration with size-exclusion liquid chromatography for high yield isolation of extracellular vesicles preserving intact biophysical and functional properties (277 citations)

In his most recent research, the most cited papers focused on:

  • Gene
  • DNA
  • Enzyme

His main research concerns Genetics, Oligonucleotide, Biochemistry, Nucleic acid and Bruton's tyrosine kinase. His Oligonucleotide study incorporates themes from Genetic therapy, RNA interference and Pharmacology. His Nucleic acid research is multidisciplinary, relying on both Locked nucleic acid and Duplex, DNA.

To a larger extent, he studies Tyrosine kinase with the aim of understanding Bruton's tyrosine kinase. His Tyrosine kinase research is multidisciplinary, incorporating perspectives in Molecular biology, Transgene, Phosphorylation and Morpholino. The various areas that he examines in his Gene study include Antibody and Disease.

Best Publications

  • Extracellular vesicle in vivo biodistribution is determined by cell source, route of administration and targeting

    Oscar P. B. Wiklander;Joel Z. Nordin;Aisling O'Loughlin;Ylva Gustafsson

  • Cells release subpopulations of exosomes with distinct molecular and biological properties

    Eduard Willms;Henrik J. Johansson;Imre Mäger;Imre Mäger;Yi Lee

  • Colocalization of X-linked agammaglobulinemia and X-linked immunodeficiency genes

    J. D. Thomas;P. Sideras;C. I. E. Smith;I. Vorechovsky

  • Ultrafiltration with size-exclusion liquid chromatography for high yield isolation of extracellular vesicles preserving intact biophysical and functional properties

    Joel Z. Nordin;Yi Lee;Pieter Vader;Imre Mäger;Imre Mäger

  • Bruton's tyrosine kinase (Btk): function, regulation, and transformation with special emphasis on the PH domain.

    Abdalla J. Mohamed;Liang Yu;Carl-Magnus Bäckesjö;Leonardo Vargas

  • Early and prolonged intravenous immunoglobulin replacement therapy in childhood agammaglobulinemia: a retrospective survey of 31 patients.

    Pierre Quartier;Marianne Debré;Jacques De Blic;Rodolphe de Sauverzac

  • Interleukin 4 induces synthesis of IgE and IgG4 in human B cells.

    Mats Lundgren;Ulla Persson;Ulla Persson;Per Larsson;Carl Magnusson

  • Subcutaneous immunoglobulin replacement in patients with primary antibody deficiencies: safety and costs

    A.Gardulf Rn;L Hammarström;R Gustafson;T Nyström

  • Design of a peptide-based vector, PepFect6, for efficient delivery of siRNA in cell culture and systemically in vivo.

    Samir E L Andaloussi;Taavi Lehto;Imre Mäger;Katri Rosenthal-Aizman

  • Oligonucleotide Therapies: The Past and the Present.

    Karin E. Lundin;Olof Gissberg;C.I. Edvard Smith

  • Home treatment of hypogammaglobulinaemia with subcutaneous gammaglobulin by rapid infusion.

    L. Hammarstrom;A. Gardulf;C.I. Edvard Smith

  • Bruton's tyrosine kinase: cell biology, sequence conservation, mutation spectrum, siRNA modifications, and expression profiling.

    Jessica M Lindvall;K Emelie M Blomberg;Jouni Väliaho;Leonardo Vargas

  • BTKbase: the mutation database for X-linked agammaglobulinemia

    Jouni Väliaho;C.I. Edvard Smith;Mauno Vihinen

  • Hypomorphic homozygous mutations in phosphoglucomutase 3 (PGM3) impair immunity and increase serum IgE levels.

    Atfa Sassi;Sandra Lazaroski;Gang Wu;Stuart M. Haslam

  • Safety and efficacy of the mRNA BNT162b2 vaccine against SARS-CoV-2 in five groups of immunocompromised patients and healthy controls in a prospective open-label clinical trial.

    Peter Bergman;Peter Bergman;Ola Blennow;Ola Blennow;Lotta Hansson;Lotta Hansson;Stephan Mielke;Stephan Mielke

  • The subcellular Sox11 distribution pattern identifies subsets of mantle cell lymphoma: correlation to overall survival.

    Xiao Wang;A. Charlotta Asplund;Anna Porwit;Jenny Flygare

  • Dual Functions of Bruton’s Tyrosine Kinase and Tec Kinase during Fcγ Receptor-Induced Signaling and Phagocytosis

    Jenny Jongstra-Bilen;Jenny Jongstra-Bilen;Adrianet Puig Cano;Manvi Hasija;Haiyan Xiao

  • TGF-beta 1 induces germ-line transcripts of both IgA subclasses in human B lymphocytes.

    Khalid B. Islam;Lars Nilsson;Paschalis Sideras;Lennart Hammarström

  • Delivery of nucleic acids with a stearylated (RxR)4 peptide using a non-covalent co-incubation strategy.

    Taavi Lehto;Rachida Abes;Nikita Oskolkov;Julia Suhorutsenko

  • Comparative Analysis of BTK Inhibitors and Mechanisms Underlying Adverse Effects.

    H. Yesid Estupiñán;H. Yesid Estupiñán;Anna Berglöf;Rula Zain;C. I. Edvard Smith

Frequent Co-Authors

Lennart Hammarström
Lennart Hammarström Karolinska Institute
Samir El Andaloussi
Samir El Andaloussi Karolinska Institute
Mauno Vihinen
Mauno Vihinen Lund University
Jesper Wengel
Jesper Wengel Aalborg University
Birger Christensson
Birger Christensson Karolinska Institute
Matthew J.A. Wood
Matthew J.A. Wood University of Oxford
Ülo Langel
Ülo Langel Stockholm University
Lennart Nilsson
Lennart Nilsson Karolinska Institute
Hans D. Ochs
Hans D. Ochs University of Washington
Paschalis Sideras
Paschalis Sideras Academy of Athens

External Links

Personal website of C. I. Edvard Smith

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