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Jesper Wengel

Jesper Wengel

D-Index & Metrics

Chemistry

D-Index
74
Citations
27459
World Ranking
4586
National Ranking
35

Overview

Jesper Wengel is affiliated with the University of Southern Denmark in Denmark, contributing extensively to research in biochemistry, genetics, and molecular biology. Their work encompasses a range of topics with a strong emphasis on molecular biology, cellular and molecular neuroscience, immunology, epidemiology, and radiology-related disciplines.

The scientist's primary fields of study include:

  • Biochemistry, Genetics and Molecular Biology
  • Medicine

Jesper Wengel's research interests are concentrated in several main topics such as advanced biosensing and bioanalysis techniques, RNA interference and gene delivery, DNA and nucleic acid chemistry, genetic neurodegenerative diseases, monoclonal and polyclonal antibodies research, RNA and protein synthesis mechanisms, and RNA research and splicing.

  • Advanced biosensing and bioanalysis techniques
  • RNA Interference and Gene Delivery
  • DNA and Nucleic Acid Chemistry
  • Genetic Neurodegenerative Diseases
  • Monoclonal and Polyclonal Antibodies Research
  • RNA and protein synthesis mechanisms
  • RNA Research and Splicing

Jesper Wengel has published numerous papers, some of which have received citations reflecting their impact within their fields. Notable recent publications include:

  • "NickFect type of cell-penetrating peptides present enhanced efficiency for microRNA-146a delivery into dendritic cells and during skin inflammation" (2020, Biomaterials)
  • "Dual role of the miR-146 family in rhinovirus-induced airway inflammation and allergic asthma exacerbation" (2021, Clinical and Translational Medicine)
  • "Improved Cancer Targeting by Multimerizing Aptamers on Nanoscaffolds" (2020, Molecular Therapy - Nucleic Acids)
  • "Chirality transmission in macromolecular domains" (2022, Nature Communications)
  • "Can Vitamin B12 Assist the Internalization of Antisense LNA Oligonucleotides into Bacteria?" (2021, Antibiotics)

Their publications are frequently found in journals such as Molecular Therapy - Nucleic Acids, bioRxiv (Cold Spring Harbor Laboratory), Bioconjugate Chemistry, Chemistry - A European Journal, and Nucleic Acid Therapeutics.

  • Molecular Therapy - Nucleic Acids
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Bioconjugate Chemistry
  • Chemistry - A European Journal
  • Nucleic Acid Therapeutics

The scientist has collaborated with various researchers, including Per T. Jørgensen, Chenguang Lou, Smith Rjh, Rula Zain, and Mathias Bogetoft Danielsen, contributing to a range of joint studies and publications.

  • Per T. Jørgensen
  • Chenguang Lou
  • Smith Rjh
  • Rula Zain
  • Mathias Bogetoft Danielsen

Best Publications

  • LNA (Locked Nucleic Acids): Synthesis of the adenine, cytosine, guanine, 5-methylcytosine, thymine and uracil bicyclonucleoside monomers, oligomerisation, and unprecedented nucleic acid recognition

    Alexei A. Koshkin;Sanjay K. Singh;Poul Nielsen;Vivek K. Rajwanshi

  • Phytochemistry of the genus Piper

    Virinder S. Parmar;Subhash C. Jain;Kirpal S. Bisht;Rajni Jain

  • LNA (Locked Nucleic Acid): High-Affinity Targeting of Complementary RNA and DNA†

    Birte Vester;Jesper Wengel

  • LNA: a versatile tool for therapeutics and genomics

    Michael Petersen;Jesper Wengel

  • LNA (locked nucleic acids): synthesis and high-affinity nucleic acid recognition

    Sanjay K. Singh;Alexei A. Koshkin;Jesper Wengel;Poul Nielsen

  • Potent and nontoxic antisense oligonucleotides containing locked nucleic acids

    Claes R Wahlestedt;Peter Salmi;Liam Good;Johanna Kela

  • Synthetic genetic polymers capable of heredity and evolution

    Vitor B. Pinheiro;Alexander I. Taylor;Christopher Cozens;Mikhail Abramov

  • Synthesis of 3‘-C- and 4‘-C-Branched Oligodeoxynucleotides and the Development of Locked Nucleic Acid (LNA)

    Jesper Wengel

  • LNA (Locked Nucleic Acid): An RNA Mimic Forming Exceedingly Stable LNA:LNA Duplexes

    Alexei Koshkin;Poul Nielsen;Michael Meldgaard;Vivek Kumar Rajwanshi

  • A large-scale chemical modification screen identifies design rules to generate siRNAs with high activity, high stability and low toxicity

    Jesper B. Bramsen;Maria B. Laursen;Anne F. Nielsen;Thomas B. Hansen

  • Locked Nucleic Acid (LNA) Recognition of RNA: NMR Solution Structures of LNA:RNA Hybrids

    Michael Petersen;Kent Bondensgaard;Jesper Wengel;Jens Peter Jacobsen

  • LNA compositions and uses thereof

    Jesper Wengel;Sakari Kauppinen

  • The first analogues of LNA (locked nucleic acids): phosphorothioate-LNA and 2'-thio-LNA.

    Ravindra Kumar;Sanjay K. Singh;Alexei A. Koshkin;Vivek K. Rajwanshi

  • Locked vs. unlocked nucleic acids (LNAvs.UNA): contrasting structures work towards common therapeutic goals

    Meghan A. Campbell;Jesper Wengel

  • The effect of chemical modification and nanoparticle formulation on stability and biodistribution of siRNA in mice.

    Shan Gao;Frederik Dagnaes-Hansen;Ebbe Juel Bech Nielsen;Jesper Wengel

  • Locked nucleic acid: a potent nucleic acid analog in therapeutics and biotechnology.

    Jan Stenvang Jepsen;Mads D. Sørensen;Jesper Wengel

  • The conformations of locked nucleic acids (LNA).

    Michael Petersen;Christina B. Nielsen;Katrine E. Nielsen;Gitte A. Jensen

  • Improved silencing properties using small internally segmented interfering RNAs

    Jesper B. Bramsen;Maria B. Laursen;Christian K. Damgaard;Suzy W. Lena

  • Structural studies of LNA:RNA duplexes by NMR: conformations and implications for RNase H activity.

    Kent Bondensgaard;Michael Petersen;Sanjay K. Singh;Vivek K. Rajwanshi

  • Locked nucleic acids: Promising nucleic acid analogs for therapeutic applications

    Rakesh N. Veedu;Jesper Wengel

  • Phytochemistry of the Genus Piper

    V. S. Parmar

Frequent Co-Authors

Carl Erik Olsen
Carl Erik Olsen University of Copenhagen
Virinder S. Parmar
Virinder S. Parmar City University of New York
Erik B. Pedersen
Erik B. Pedersen University of Southern Denmark
Jørgen Kjems
Jørgen Kjems Aarhus University
Nuno F. Azevedo
Nuno F. Azevedo University of Porto
C. I. Edvard Smith
C. I. Edvard Smith Karolinska University Hospital
Michael J. Gait
Michael J. Gait MRC Laboratory of Molecular Biology
Sakari Kauppinen
Sakari Kauppinen Aalborg University
Claus J. Nielsen
Claus J. Nielsen University of Oslo

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