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Sakari Kauppinen

Sakari Kauppinen

D-Index & Metrics

Biology and Biochemistry

D-Index
82
Citations
33138
World Ranking
3631
National Ranking
38

Overview

Sakari Kauppinen is affiliated with Aalborg University in Denmark and has produced research primarily in the fields of Biochemistry, Genetics and Molecular Biology, as well as Medicine. Their work spans multiple subfields, notably Molecular Biology, Cancer Research, Epidemiology, Control and Systems Engineering, and Electrical and Electronic Engineering.

The main topics explored in Kauppinen's research include:

  • Cancer-related molecular mechanisms research
  • MicroRNA in disease regulation
  • Circular RNAs in diseases
  • RNA Interference and Gene Delivery
  • RNA Research and Splicing
  • RNA modifications and cancer
  • Liver Disease Diagnosis and Treatment

Recent publication venues where Kauppinen has contributed extensively include:

  • Non-Coding RNA
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Nature Communications
  • Frontiers in Pharmacology
  • Scientific Reports

Kauppinen's research output features several notable papers, including:

  • An intranasal ASO therapeutic targeting SARS-CoV-2, 2022, Nature Communications
  • A MicroRNA Linking Human Positive Selection and Metabolic Disorders, 2020, Cell
  • Clinical advances of RNA therapeutics for treatment of neurological and neuromuscular diseases, 2022, RNA Biology
  • Clinical and functional significance of circular RNAs in cytogenetically normal AML, 2020, Blood Advances
  • Targeting the NRF2 pathway for disease modification in neurodegenerative diseases: mechanisms and therapeutic implications, 2024, Frontiers in Pharmacology

Their collaborative work frequently involves several coauthors, including:

  • Andreas Petri
  • Riccardo Panella
  • Shizuka Uchida
  • Anja Holm
  • Dimitrios Papaioannou

Best Publications

  • Treatment of HCV Infection by Targeting MicroRNA

    Harry L A Janssen;Hendrik W Reesink;Eric J Lawitz;Stefan Zeuzem

  • Therapeutic Silencing of MicroRNA-122 in Primates with Chronic Hepatitis C Virus Infection

    Robert E. Lanford;Elisabeth S. Hildebrandt-Eriksen;Andreas Petri;Robert Persson

  • LNA-mediated microRNA silencing in non-human primates

    Joacim Elmén;Morten Lindow;Sylvia Schütz;Matthew Lawrence

  • MicroRNA Expression in Zebrafish Embryonic Development

    Erno Wienholds;Wigard P. Kloosterman;Eric Miska;Ezequiel Alvarez-Saavedra

  • Loss of microRNA cluster miR-29a/b-1 in sporadic Alzheimer's disease correlates with increased BACE1/beta-secretase expression.

    Sébastien S. Hébert;Katrien Horré;Laura Nicolaï;Aikaterini S. Papadopoulou

  • Sensitive and specific detection of microRNAs by northern blot analysis using LNA-modified oligonucleotide probes

    Anna Válóczi;Csaba Hornyik;Nóra Varga;József Burgyán

  • Antagonism of microRNA-122 in mice by systemically administered LNA-antimiR leads to up-regulation of a large set of predicted target mRNAs in the liver

    Joacim Elmén;Morten Lindow;Asli Silahtaroglu;Mads Bak

  • Silencing of microRNA families by seed-targeting tiny LNAs.

    Susanna Obad;Camila O dos Santos;Andreas Petri;Markus Heidenblad

  • In situ detection of miRNAs in animal embryos using LNA-modified oligonucleotide probes

    Wigard P Kloosterman;Erno Wienholds;Ewart de Bruijn;Sakari Kauppinen

  • Altered MicroRNA Expression Confined to Specific Epithelial Cell Subpopulations in Breast Cancer

    Lorenzo F. Sempere;Mette Christensen;Asli Silahtaroglu;Mads Bak

  • Development of microRNA therapeutics is coming of age

    Eva van Rooij;Sakari Kauppinen

  • Inhibition of microRNA function by antimiR oligonucleotides

    Jan Stenvang;Andreas Petri;Morten Lindow;Susanna Obad

  • Diagnostic and Prognostic MicroRNAs in Stage II Colon Cancer

    Troels Schepeler;Jørgen T. Reinert;Marie S. Ostenfeld;Lise L. Christensen

  • MicroRNA expression in the adult mouse central nervous system

    Mads Bak;Asli Silahtaroglu;Morten Møller;Mette Christensen

  • A functional screen implicates microRNA-138-dependent regulation of the depalmitoylation enzyme APT1 in dendritic spine morphogenesis

    Gabriele Siegel;Gregor Obernosterer;Roberto Fiore;Martin Oehmen

  • MicroRNA-138 regulates osteogenic differentiation of human stromal (mesenchymal) stem cells in vivo

    Tilde Eskildsen;Hanna Taipaleenmäki;Jan Stenvang;Basem M. Abdallah

  • LNA-modified oligonucleotides mediate specific inhibition of microRNA function

    Ulf Andersson Ørom;Sakari Kauppinen;Anders H. Lund

  • Homologous domains in Trichoderma reesei cellulolytic enzymes: gene sequence and expression of cellobiohydrolase II.

    Tuula T. Teeri;Päivi Lehtovaara;Sakari Kauppinen;Irma Salovuori

  • Therapeutic inhibition of the miR-34 family attenuates pathological cardiac remodeling and improves heart function

    Bianca C Bernardo;Xiao Ming Gao;Catherine E Winbanks;Esther J H Boey

  • MicroRNA-31 functions as an oncogenic microRNA in mouse and human lung cancer cells by repressing specific tumor suppressors

    Xi Liu;Lorenzo F. Sempere;Haoxu Ouyang;Vincent A. Memoli

Frequent Co-Authors

Niels Tommerup
Niels Tommerup University of Copenhagen
Murray Korc
Murray Korc University of California, Irvine
Jesper Wengel
Jesper Wengel Aalborg University
Anders H. Lund
Anders H. Lund University of Copenhagen
Clara D. Bloomfield
Clara D. Bloomfield The Ohio State University
Ronald H. A. Plasterk
Ronald H. A. Plasterk University of Amsterdam
George S. Vassiliou
George S. Vassiliou University of Cambridge
Wigard P. Kloosterman
Wigard P. Kloosterman Utrecht University
Anders M. Näär
Anders M. Näär University of California, Berkeley
Peter Arctander
Peter Arctander University of Copenhagen

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