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Carlos Fernández-Hernando

Carlos Fernández-Hernando

D-Index & Metrics

Medicine

D-Index
85
Citations
22563
World Ranking
14745
National Ranking
7457

Overview

Carlos Fernández-Hernando is affiliated with Yale University in the United States and has contributed extensively to research in biochemistry, genetics, molecular biology, and medicine. Their work spans various subfields including molecular biology, cancer research, immunology, surgery, and cardiology and cardiovascular medicine.

Their research prominently addresses several main topics such as:

  • MicroRNA in disease regulation
  • Cancer-related molecular mechanisms research
  • Atherosclerosis and cardiovascular diseases
  • Lipid metabolism and disorders
  • Cholesterol and lipid metabolism
  • Liver disease diagnosis and treatment
  • Cancer, lipids, and metabolism

Frequent co-authors working alongside Fernández-Hernando include Yajaira Suárez, Xinbo Zhang, Noemí Rotllán, Nathan L. Price, and Alberto Canfrán-Duque, reflecting collaborative efforts in advancing understanding in these scientific areas.

They have published a significant number of papers in respected venues, with the most common publication outlets being:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Nature Communications
  • Arteriosclerosis Thrombosis and Vascular Biology
  • JCI Insight
  • Proceedings of the National Academy of Sciences

Representative recent papers authored or co-authored by Fernández-Hernando include:

  • Smooth Muscle Cell Reprogramming in Aortic Aneurysms, 2020, Cell Stem Cell
  • Loss of endothelial glucocorticoid receptor accelerates diabetic nephropathy, 2021, Nature Communications
  • ANGPTL4: a multifunctional protein involved in metabolism and vascular homeostasis, 2020, Current Opinion in Hematology
  • Desmosterol suppresses macrophage inflammasome activation and protects against vascular inflammation and atherosclerosis, 2021, Proceedings of the National Academy of Sciences
  • Cav-1 (Caveolin-1) Deficiency Increases Autophagy in the Endothelium and Attenuates Vascular Inflammation and Atherosclerosis, 2020, Arteriosclerosis Thrombosis and Vascular Biology

Best Publications

  • MiR-33 Contributes to the Regulation of Cholesterol Homeostasis

    Katey J. Rayner;Yajaira Suárez;Alberto Dávalos;Saj Parathath

  • Dicer Dependent MicroRNAs Regulate Gene Expression and Functions in Human Endothelial Cells

    Yajaira Suárez;Carlos Fernández-Hernando;Jordan S. Pober;William C. Sessa

  • Inhibition of miR-33a/b in non-human primates raises plasma HDL and lowers VLDL triglycerides

    Katey J. Rayner;Christine C. Esau;Farah N. Hussain;Allison L. McDaniel

  • Antagonism of miR-33 in mice promotes reverse cholesterol transport and regression of atherosclerosis

    Katey J. Rayner;Frederick J. Sheedy;Christine C. Esau;Farah N. Hussain

  • miR-33a/b contribute to the regulation of fatty acid metabolism and insulin signaling.

    Alberto Dávalos;Leigh Goedeke;Peter Smibert;Cristina M. Ramírez

  • Dicer-dependent endothelial microRNAs are necessary for postnatal angiogenesis.

    Yajaira Suárez;Carlos Fernández-Hernando;Jun Yu;Scott A. Gerber

  • MicroRNAs in lipid metabolism

    Carlos Fernández-Hernando;Yajaira Suárez;Katey J Rayner;Kathryn J Moore

  • MicroRNA-30c reduces hyperlipidemia and atherosclerosis in mice by decreasing lipid synthesis and lipoprotein secretion

    James Soh;Jahangir Iqbal;Joyce Queiroz;Carlos Fernandez-Hernando

  • Loss of Akt1 Leads to Severe Atherosclerosis and Occlusive Coronary Artery Disease

    Carlos Fernández-Hernando;Eric Ackah;Jun Yu;Yajaira Suárez

  • MicroRNA-758 Regulates Cholesterol Efflux Through Posttranscriptional Repression of ATP-Binding Cassette Transporter A1

    Cristina M. Ramirez;Alberto Dávalos;Leigh Goedeke;Alessandro G. Salerno

  • MicroRNAs in Metabolic Disease

    Carlos Fernández-Hernando;Cristina M. Ramírez;Leigh Goedeke;Yajaira Suárez

  • Genome-wide identification of microRNAs regulating cholesterol and triglyceride homeostasis.

    Alexandre Wagschal;S Hani Najafi-Shoushtari;S Hani Najafi-Shoushtari;Lifeng Wang;Leigh Goedeke

  • MicroRNA-148a regulates LDL receptor and ABCA1 expression to control circulating lipoprotein levels.

    Leigh Goedeke;Noemi Rotllan;Alberto Canfrán-Duque;Juan F. Aranda;Juan F. Aranda

  • Control of Cholesterol Metabolism and Plasma High-Density Lipoprotein Levels by microRNA-144

    Cristina M. Ramírez;Noemi Rotllan;Alexander V. Vlassov;Alexander V. Vlassov;Alberto Dávalos

  • Endothelial TGF-β signalling drives vascular inflammation and atherosclerosis.

    Pei-Yu Chen;Lingfeng Qin;Guangxin Li;Guangxin Li;Zheng Wang

  • Circulating MicroRNA-122 is associated with the risk of new-onset metabolic syndrome and type 2 diabetes

    Peter Willeit;Philipp Skroblin;Alexander R. Moschen;Xiaoke Yin

  • Regulation of cholesterol homeostasis.

    Leigh Goedeke;Carlos Fernández-Hernando

  • MiR-106b impairs cholesterol efflux and increases Aβ levels by repressing ABCA1 expression.

    Jaekwang Kim;Hyejin Yoon;Cristina M. Ramírez;Sang Mi Lee

  • Akt1 is critical for acute inflammation and histamine-mediated vascular leakage

    Annarita Di Lorenzo;Carlos Fernández-Hernando;Giuseppe Cirino;William C. Sessa

  • Prohibitin-1 maintains the angiogenic capacity of endothelial cells by regulating mitochondrial function and senescence

    Michael Schleicher;Benjamin R. Shepherd;Yajaira Suarez;Carlos Fernandez-Hernando

Frequent Co-Authors

Yajaira Suárez
Yajaira Suárez Yale University
William C. Sessa
William C. Sessa Pfizer (United States)
Kathryn J. Moore
Kathryn J. Moore New York University Langone Medical Center
Manuel Mayr
Manuel Mayr King's College London
Edward A. Fisher
Edward A. Fisher New York University
Jun Yu
Jun Yu Chinese University of Hong Kong
Rafael de Cabo
Rafael de Cabo National Institutes of Health
Jose M. Ordovas
Jose M. Ordovas Tufts University
Stefan Kiechl
Stefan Kiechl Innsbruck Medical University
Gerald I. Shulman
Gerald I. Shulman Yale University

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