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Diane McMahon-Pratt

Diane McMahon-Pratt

D-Index & Metrics

Microbiology

D-Index
56
Citations
8751
World Ranking
3750
National Ranking
1467

Overview

Diane McMahon-Pratt is affiliated with Yale University in the United States and has contributed to the field of Medicine through research spanning multiple subfields such as Public Health, Environmental and Occupational Health, Rheumatology, Hematology, Epidemiology, and Infectious Diseases.

Their recent publications focus extensively on topics related to parasitic diseases and immune responses, with a notable emphasis on Leishmaniasis studies. The main research topics associated with Diane McMahon-Pratt include:

  • Research on Leishmaniasis Studies
  • Eosinophilic Disorders and Syndromes
  • Platelet Disorders and Treatments
  • Trypanosoma species research and implications
  • Parasitic Diseases Research and Treatment
  • Mast cells and histamine
  • Urticaria and Related Conditions

Selected recent publications demonstrate a focus on the immune mechanisms involving Leishmania major and the role of platelet activation and DKK1 production in host responses. These works include:

  • Leishmania major-derived lipophosphoglycan influences the host's early immune response by inducing platelet activation and DKK1 production via TLR1/2 (2023), published in Frontiers in Immunology
  • Leishmania major surface components and DKK1 signalling via LRP6 promote migration and longevity of neutrophils in the infection site (2024), published in Frontiers in Immunology
  • Platelet DKK1 promotes tolerogenic dendritic cells and non-healing responses in cutaneous leishmaniasis (2025), published in bioRxiv (Cold Spring Harbor Laboratory)
  • Heterogeneity, geographic distribution, and pathogenicity of serodemes of Leishmania viannia in Colombia (2021), published in UNC Libraries

Diane McMahon-Pratt frequently collaborates with several researchers, notably Olivia C. Ihedioha, Anutr Sivakoses, Alfred L.M. Bothwell, Stephen M. Beverley, and Haley Q. Marcarian. These coauthors have contributed multiple joint publications, indicating a sustained research partnership.

Their research is primarily published in recognized venues such as:

  • Frontiers in Immunology
  • bioRxiv (Cold Spring Harbor Laboratory)
  • UNC Libraries

Best Publications

  • Leishmaniasis in Bahia, Brazil: evidence that Leishmania amazonensis produces a wide spectrum of clinical disease.

    Barral A;Pedral-Sampaio D;Grimaldi Júnior G;Momen H

  • Does the Leishmania major paradigm of pathogenesis and protection hold for New World cutaneous leishmaniases or the visceral disease

    Diane McMahon-Pratt;James Alexander

  • Disruption of CD40–CD40 Ligand Interactions Results in an Enhanced Susceptibility to Leishmania amazonensis Infection

    Lynn Soong;Jian Chao Xu;Iqbal S. Grewal;Peter Kima

  • Development of a stable Leishmania expression vector and application to the study of parasite surface antigen genes.

    Jonathan H. Lebowitz;Cara M. Coburn;Diane McMahon-Pratt;Stephen M. Beverley

  • Identification and distribution of New World Leishmania species characterized by serodeme analysis using monoclonal antibodies.

    Gabriel Grimaldi;John R. David;Diane McMahon-Pratt

  • Characterization and classification of leishmanial parasites from humans, wild mammals, and sand flies in the Amazon region of Brazil.

    Gabriel Grimaldi;Hooman Momen;Roberto D. Naiff;Diane McMahon-Pratt

  • Internalization of Leishmania mexicana Complex Amastigotes via the Fc Receptor Is Required to Sustain Infection in Murine Cutaneous Leishmaniasis

    Peter E. Kima;Stephanie L. Constant;Lynn Hannum;Maria Colmenares

  • Role of CD4+ T cells in pathogenesis associated with Leishmania amazonensis infection.

    L Soong;C H Chang;C H Chang;J Sun;B J Longley

  • Membrane glycoprotein M-2 protects against Leishmania amazonensis infection.

    J Champsi;D McMahon-Pratt

  • Intradermal Infection Model for Pathogenesis and Vaccine Studies of Murine Visceral Leishmaniasis

    Saeed Ahmed;M. Colmenares;Lynn Soong;K. Goldsmith-Pestana

  • Recombinant vaccinia viruses expressing GP46/M-2 protect against Leishmania infection.

    D McMahon-Pratt;D Rodriguez;J R Rodriguez;Y Zhang

  • Leishmania pifanoi amastigote antigens protect mice against cutaneous leishmaniasis.

    Lynn Soong;S. M. Duboise;P. Kima;D. Mcmahon-Pratt

  • A Leishmania Ortholog of Macrophage Migration Inhibitory Factor Modulates Host Macrophage Responses

    Daniela Kamir;Swen Zierow;Swen Zierow;Lin Leng;Yoonsang Cho

  • Production and characterization of species-specific monoclonal antibodies against Leishmania donovani for immunodiagnosis.

    C L Jaffe;E Bennett;G Grimaldi;D McMahon-Pratt

  • Characterization of Leishmania colombiensis sp. n (Kinetoplastida: Trypanosomatidae), a new parasite infecting humans, animals, and phlebotomine sand flies in Colombia and Panama.

    Richard D. Kreutzer;Augusto Corredor;Gabriel Grimaldi;Max Grogl

  • A Scaffold Protein, AHNAK1, Is Required for Calcium Signaling during T Cell Activation

    Didi Matza;Abdallah Badou;Koichi S. Kobayashi;Karen Goldsmith-Pestana

  • The Wnt Antagonist Dickkopf-1 Promotes Pathological Type 2 Cell-Mediated Inflammation.

    Wook Jin Chae;Allison K. Ehrlich;Pamela Y. Chan;Alexandra M. Teixeira

  • Murine visceral leishmaniasis: IgM and polyclonal B‐cell activation lead to disease exacerbation

    Eszter Deak;Asha Jayakumar;Ka Wing Cho;Karen Goldsmith-Pestana

  • Cutaneous leishmaniasis: review of 59 cases seen at the National Institutes of Health.

    Peter C. Melby;Richard D. Kreutzer;Richard D. Kreutzer;Richard D. Kreutzer;Diane McMahon-Pratt;Diane McMahon-Pratt;Diane McMahon-Pratt;Albert A. Gam;Albert A. Gam;Albert A. Gam

  • Developmental Life Cycle of Leishmania—Cultivation and Characterization of Cultured Extracellular Amastigotes

    A A Pan;S M Duboise;S Eperon;L Rivas

Frequent Co-Authors

Lynn Soong
Lynn Soong The University of Texas Medical Branch at Galveston
Nancy G. Saravia
Nancy G. Saravia Tulane University
Nancy H. Ruddle
Nancy H. Ruddle Yale University
Richard A. Flavell
Richard A. Flavell Yale University
Jeffrey J. Shaw
Jeffrey J. Shaw Universidade de São Paulo
Jenefer M. Blackwell
Jenefer M. Blackwell Telethon Kids Institute
Robert B. Tesh
Robert B. Tesh Yale University
Marie-Anne Shaw
Marie-Anne Shaw University of Leeds
Stephen M. Beverley
Stephen M. Beverley Washington University in St. Louis
Rupert J. Quinnell
Rupert J. Quinnell University of Leeds

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