Peter T. Lansbury

Research.com Recognitions

• 2023 - Research.com Biology and Biochemistry in Portugal Leader Award
• 2022 - Research.com Biology and Biochemistry in Portugal Leader Award
• 1991 - Fellow of Alfred P. Sloan Foundation
• 1963 - Fellow of Alfred P. Sloan Foundation

Overview

Best Publications

• Seeding “one-dimensional crystallization” of amyloid: A pathogenic mechanism in Alzheimer's disease and scrapie?

  Joseph T. Jarrett;Peter T. Lansbury

  3242
  Citations

• The carboxy terminus of the beta amyloid protein is critical for the seeding of amyloid formation: implications for the pathogenesis of Alzheimer's disease.

  Joseph T. Jarrett;Elizabeth P. Berger;Peter T. Lansbury

  3133
  Citations

• Impaired degradation of mutant α-synuclein by chaperone-mediated autophagy

  Ana Maria Cuervo;Leonidas Stefanis;Ross Fredenburg;Peter T. Lansbury

  2442
  Citations

• Acceleration of oligomerization, not fibrillization, is a shared property of both α-synuclein mutations linked to early-onset Parkinson's disease: Implications for pathogenesis and therapy

  Kelly A. Conway;Seung Jae Lee;Jean Christophe Rochet;Tomas T. Ding

  2426
  Citations

• Protofibrils, pores, fibrils, and neurodegeneration: separating the responsible protein aggregates from the innocent bystanders.

  Byron Caughey;Peter T. Lansbury

  2145
  Citations

• MODELS OF AMYLOID SEEDING IN ALZHEIMER'S DISEASE AND SCRAPIE: Mechanistic Truths and Physiological Consequences of the Time-Dependent Solubility of Amyloid Proteins

  James D. Harper;Peter T. Lansbury

  2083
  Citations

• Neurodegenerative disease: amyloid pores from pathogenic mutations.

  Hilal A. Lashuel;Dean Hartley;Benjamin M. Petre;Thomas Walz

  1935
  Citations

• NACP, a protein implicated in Alzheimer's disease and learning, is natively unfolded.

  Paul H. Weinreb;Weiguo Zhen;Anna W. Poon;Kelly A. Conway

  1929
  Citations

• Accelerated in vitro fibril formation by a mutant alpha-synuclein linked to early-onset Parkinson disease.

  Kelly A. Conway;James D. Harper;Peter T. Lansbury

  1854
  Citations

• Amyloid fibrillogenesis: themes and variations.

  Jean-Christophe Rochet;Peter T Lansbury

  1670
  Citations

• Kinetic Stabilization of the α-Synuclein Protofibril by a Dopamine-α-Synuclein Adduct

  Kelly A. Conway;Jean-Christophe Rochet;Robert M. Bieganski;Peter T. Lansbury

  1644
  Citations

• Cell-free formation of protease-resistant prion protein

  David A. Kocisko;David A. Kocisko;Jon H. Come;Jon H. Come;Suzette A. Priola;Bruce Chesebro

  1215
  Citations

• The UCH-L1 Gene Encodes Two Opposing Enzymatic Activities that Affect α-Synuclein Degradation and Parkinson's Disease Susceptibility

  Yichin Liu;Lara Fallon;Hilal A. Lashuel;Zhihua Liu

  1102
  Citations

• α-Synuclein, Especially the Parkinson's Disease-associated Mutants, Forms Pore-like Annular and Tubular Protofibrils

  Hilal A. Lashuel;Benjamin M. Petre;Joseph Wall;Martha Simon

  1038
  Citations

• Amyloid diseases: abnormal protein aggregation in neurodegeneration.

  Edward H. Koo;Peter T. Lansbury;Jeffery W. Kelly

  1006
  Citations

• Fibrils Formed in Vitro from α-Synuclein and Two Mutant Forms Linked to Parkinson's Disease are Typical Amyloid†

  Kelly A. Conway;James D. Harper;Peter T. Lansbury

  992
  Citations

• Observation of metastable Aβ amyloid protofibrils by atomic force microscopy

  James D. Harper;Stanislaus S. Wong;Charles M. Lieber;Peter T. Lansbury

  942
  Citations

• Vesicle Permeabilization by Protofibrillar α-Synuclein: Implications for the Pathogenesis and Treatment of Parkinson's Disease†

  Michael J. Volles;Seung-Jae Lee;Jean-Christophe Rochet;Mark D. Shtilerman

  887
  Citations

• A century-old debate on protein aggregation and neurodegeneration enters the clinic

  Peter T. Lansbury;Hilal A. Lashuel

  831
  Citations

• Evolution of amyloid: What normal protein folding may tell us about fibrillogenesis and disease

  Peter T. Lansbury

  808
  Citations