Paul H. Weinreb

Overview

Best Publications

• The antibody aducanumab reduces Aβ plaques in Alzheimer’s disease

  Jeff Sevigny;Ping Chiao;Thierry Bussière;Paul H Weinreb

  3210
  Citations

• NACP, a protein implicated in Alzheimer's disease and learning, is natively unfolded.

  Paul H. Weinreb;Weiguo Zhen;Anna W. Poon;Kelly A. Conway

  1929
  Citations

• CHARACTERIZATION OF SFP, A BACILLUS SUBTILIS PHOSPHOPANTETHEINYL TRANSFERASE FOR PEPTIDYL CARRIER PROTEIN DOMAINS IN PEPTIDE SYNTHETASES

  Luis E. N. Quadri;Paul H. Weinreb;Ming Lei;Michiko M. Nakano

  852
  Citations

• Identification of a Mycobacterium tuberculosis gene cluster encoding the biosynthetic enzymes for assembly of the virulence-conferring siderophore mycobactin.

  Luis E.N. Quadri;Jason Sello;Thomas A. Keating;Paul H. Weinreb

  546
  Citations

• Partial Inhibition of Integrin αvβ6 Prevents Pulmonary Fibrosis without Exacerbating Inflammation

  Gerald S. Horan;Susan Wood;Victor Ona;Dan Jun Li

  453
  Citations

• The alpha(v)beta6 integrin receptor for Foot-and-mouth disease virus is expressed constitutively on the epithelial cells targeted in cattle.

  Paul Monaghan;Sarah Gold;Jennifer Simpson;Zhidong Zhang

  407
  Citations

• The core Alzheimer's peptide NAC forms amyloid fibrils which seed and are seeded by β-amyloid: is NAC a common trigger or target in neurodegenerative disease?

  Hogyu Han;Paul H. Weinreb;Peter T. Lansbury

  393
  Citations

• Stromal features are predictive of disease mortality in oral cancer patients

  Daniel Marsh;Krishna Suchak;Karwan A Moutasim;Sabarinath Vallath

  359
  Citations

• Post-translational modification of polyketide and nonribosomal peptide synthases.

  Christopher T Walsh;Amy M Gehring;Paul H Weinreb;Luis En Quadri

  308
  Citations

• Inhibition of Integrin αvβ6, an Activator of Latent Transforming Growth Factor-β, Prevents Radiation-induced Lung Fibrosis

  Khalid Puthawala;Nicos Hadjiangelis;Steven C. Jacoby;Emmanuel Bayongan

  306
  Citations

• Interleukin-1β Causes Acute Lung Injury via αvβ5 and αvβ6 Integrin–Dependent Mechanisms

  Michael T. Ganter;Jérémie Roux;Byron Miyazawa;Marybeth Howard

  246
  Citations

• Structural and kinetic basis for the selectivity of aducanumab for aggregated forms of amyloid-β

  J.W. Arndt;F. Qian;B.A. Smith;C. Quan

  240
  Citations

• Mice that lack activity of αvβ6- and αvβ8-integrins reproduce the abnormalities of Tgfb1- and Tgfb3-null mice

  Poshala Aluwihare;Zhenyu Mu;Zhicheng Zhao;Dawen Yu

  240
  Citations

• Lysophosphatidic Acid Induces αvβ6 Integrin-Mediated TGF-β Activation via the LPA2 Receptor and the Small G Protein Gαq

  Ming Yan Xu;Joanne Porte;Alan J. Knox;Paul H. Weinreb

  240
  Citations

• Function-blocking Integrin αvβ6 Monoclonal Antibodies DISTINCT LIGAND-MIMETIC AND NONLIGAND-MIMETIC CLASSES

  Paul H. Weinreb;Kenneth J. Simon;Paul Rayhorn;William J. Yang

  234
  Citations

• αvβ6 Integrin Regulates Renal Fibrosis and Inflammation in Alport Mouse

  Kyungmin Hahm;Matvey E. Lukashev;Yi Luo;William J. Yang

  220
  Citations

• Constitutively Activated Stat3 Induces Tumorigenesis and Enhances Cell Motility of Prostate Epithelial Cells through Integrin β6

  Janeen Azare;Kenneth Leslie;Hikmat Al-Ahmadie;William Gerald

  211
  Citations

• Overexpression of the alpha v beta 6 integrin in cervical squamous cell carcinoma is a prognostic factor for decreased survival

  S Hazelbag;GG Kenter;A Gorter;EJ Dreef

  206
  Citations

• Obtustatin A Potent Selective Inhibitor of α1β1 Integrin in Vitro and Angiogenesis in Vivo

  Cezary Marcinkiewicz;Paul H. Weinreb;Juan J. Calvete;Dariusz G. Kisiel

  205
  Citations

• Enhanced potency of human Sonic hedgehog by hydrophobic modification.

  Frederick R. Taylor;Dingyi Wen;Ellen A. Garber;Amie N. Carmillo

  200
  Citations