World's Best Scientists 2026 revealed!

D-Index & Metrics

Biology and Biochemistry

D-Index
98
Citations
36369
World Ranking
1659
National Ranking
926

Neuroscience

D-Index
97
Citations
36136
World Ranking
820
National Ranking
448

Claudio Soto publication distribution in Neuroscience in 2026

The chart shows the distribution of publications by all Research.com ranked scientists in the field of Neuroscience in 2026. The highlighted bar marks where Claudio Soto sits on this spectrum.

38–47 publications: 18 scientists 48–57 publications: 79 scientists 58–67 publications: 193 scientists 68–77 publications: 323 scientists 78–87 publications: 406 scientists 88–97 publications: 452 scientists 98–107 publications: 539 scientists 108–117 publications: 505 scientists 118–127 publications: 522 scientists 128–137 publications: 469 scientists 138–147 publications: 456 scientists 148–157 publications: 459 scientists 158–167 publications: 397 scientists 168–177 publications: 383 scientists 178–187 publications: 350 scientists 188–197 publications: 302 scientists 198–207 publications: 306 scientists 208–217 publications: 262 scientists 218–227 publications: 242 scientists 228–237 publications: 220 scientists 238–247 publications: 203 scientists 248–257 publications: 174 scientists 258–267 publications: 176 scientists 268–277 publications: 175 scientists 278–287 publications: 125 scientists 288–297 publications: 116 scientists 298–307 publications: 127 scientists 308–317 publications: 128 scientists 318–327 publications: 99 scientists 328–337 publications: 89 scientists 338–347 publications: 78 scientists 348–357 publications: 96 scientists 358–367 publications: 66 scientists 368–377 publications: 59 scientists 378–387 publications: 65 scientists 388–397 publications: 54 scientists 398–407 publications: 48 scientists 408–417 publications: 49 scientists 418–427 publications: 34 scientists 428–437 publications: 31 scientists 438–447 publications: 30 scientists 448–457 publications: 31 scientists 458–467 publications: 36 scientists 468–477 publications: 40 scientists 478–487 publications: 35 scientists 488–497 publications: 30 scientists 498–507 publications: 23 scientists 508–517 publications: 26 scientists 518–527 publications: 20 scientists 528–537 publications: 23 scientists 538–547 publications: 20 scientists 548–557 publications: 20 scientists 558–567 publications: 17 scientists 568–577 publications: 14 scientists 578–587 publications: 20 scientists 588–597 publications: 20 scientists 598–607 publications: 19 scientists 608–617 publications: 18 scientists 618–627 publications: 17 scientists 628–637 publications: 11 scientists 638–647 publications: 11 scientists 648–657 publications: 11 scientists 658–667 publications: 8 scientists 668–677 publications: 7 scientists 678–687 publications: 11 scientists 688–697 publications: 10 scientists 698–707 publications: 4 scientists 708–717 publications: 6 scientists 718–727 publications: 5 scientists 728–737 publications: 5 scientists 738–747 publications: 9 scientists 748–757 publications: 9 scientists 758–767 publications: 3 scientists 768–777 publications: 7 scientists 778–787 publications: 7 scientists 788–797 publications: 6 scientists 798–807 publications: 2 scientists 808–817 publications: 2 scientists 818–827 publications: 7 scientists 828–837 publications: 0 scientists 838–847 publications: 9 scientists 848–857 publications: 3 scientists 858–867 publications: 1 scientists 868–877 publications: 3 scientists 878–886 publications: 6 scientists 887+ publications: 100 scientists
38 publications 887+

This scientist: 300 publications — 82nd percentile

82% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 887 publications or more.

Claudio Soto D-index placement in Neuroscience in 2026

The chart shows the D-index (discipline H-index) distribution of Neuroscience scientists ranked by Research.com in 2026. The highlighted bar marks where Claudio Soto sits on this spectrum.

30–31 D-Index: 42 scientists 32–33 D-Index: 172 scientists 34–35 D-Index: 296 scientists 36–37 D-Index: 435 scientists 38–39 D-Index: 459 scientists 40–41 D-Index: 456 scientists 42–43 D-Index: 467 scientists 44–45 D-Index: 478 scientists 46–47 D-Index: 512 scientists 48–49 D-Index: 435 scientists 50–51 D-Index: 425 scientists 52–53 D-Index: 418 scientists 54–55 D-Index: 392 scientists 56–57 D-Index: 357 scientists 58–59 D-Index: 334 scientists 60–61 D-Index: 328 scientists 62–63 D-Index: 260 scientists 64–65 D-Index: 278 scientists 66–67 D-Index: 239 scientists 68–69 D-Index: 250 scientists 70–71 D-Index: 210 scientists 72–73 D-Index: 200 scientists 74–75 D-Index: 189 scientists 76–77 D-Index: 170 scientists 78–79 D-Index: 146 scientists 80–81 D-Index: 113 scientists 82–83 D-Index: 126 scientists 84–85 D-Index: 100 scientists 86–87 D-Index: 84 scientists 88–89 D-Index: 99 scientists 90–91 D-Index: 84 scientists 92–93 D-Index: 85 scientists 94–95 D-Index: 72 scientists 96–97 D-Index: 76 scientists 98–99 D-Index: 45 scientists 100–101 D-Index: 49 scientists 102–103 D-Index: 43 scientists 104–105 D-Index: 32 scientists 106–107 D-Index: 45 scientists 108–109 D-Index: 50 scientists 110–111 D-Index: 32 scientists 112–113 D-Index: 39 scientists 114–115 D-Index: 32 scientists 116–117 D-Index: 29 scientists 118–119 D-Index: 27 scientists 120–121 D-Index: 19 scientists 122–123 D-Index: 23 scientists 124–125 D-Index: 27 scientists 126–127 D-Index: 16 scientists 128–129 D-Index: 24 scientists 130–131 D-Index: 13 scientists 132–133 D-Index: 21 scientists 134–135 D-Index: 17 scientists 136–137 D-Index: 14 scientists 138–139 D-Index: 15 scientists 140–141 D-Index: 10 scientists 142–143 D-Index: 10 scientists 144–145 D-Index: 13 scientists 146–147 D-Index: 9 scientists 148–149 D-Index: 8 scientists 150–151 D-Index: 6 scientists 152–153 D-Index: 6 scientists 154–155 D-Index: 7 scientists 156–157 D-Index: 7 scientists 158–159 D-Index: 10 scientists 160–161 D-Index: 4 scientists 162 D-Index: 8 scientists 163+ D-Index: 100 scientists
30 D-Index 163+

This scientist: 97 D-Index — 92nd percentile

92% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 163 D-Index or more.

Overview

Claudio Soto is affiliated with The University of Texas Health Science Center at Houston in the United States. Their research focuses primarily on neurodegenerative diseases, with a substantial contribution to the understanding of molecular mechanisms underlying disorders such as Parkinson's disease and Alzheimer's disease.

The scientist has published extensively in fields related to Medicine and Biochemistry, Genetics and Molecular Biology. Within these domains, their work spans several subfields, including Neurology, Molecular Biology, Physiology, Cellular and Molecular Neuroscience, and Surgery.

Claudio Soto's research topics cover a variety of areas in neurological and neurodegenerative disease studies. Prominent topics include:

  • Alzheimer's disease research and treatments
  • Parkinson's Disease Mechanisms and Treatments
  • Prion Diseases and Protein Misfolding
  • Neurological disorders and treatments
  • Neurological diseases and metabolism
  • Botulinum Toxin and Related Neurological Disorders
  • Trace Elements in Health

The scientist has contributed to several frequent publication venues, reflecting their research impact and focus areas. These venues include:

  • Alzheimer s & Dementia
  • Acta Neuropathologica Communications
  • Cells
  • Frontiers in Aging Neuroscience
  • bioRxiv (Cold Spring Harbor Laboratory)

Among recent significant papers, the following publications are noted, with their respective years and publication sources:

  • Discriminating α-synuclein strains in Parkinson's disease and multiple system atrophy, 2020, Nature
  • Assessment of heterogeneity among participants in the Parkinson's Progression Markers Initiative cohort using α-synuclein seed amplification: a cross-sectional study, 2023, The Lancet Neurology
  • A biological definition of neuronal α-synuclein disease: towards an integrated staging system for research, 2024, The Lancet Neurology
  • High diagnostic performance of independent alpha-synuclein seed amplification assays for detection of early Parkinson's disease, 2021, Acta Neuropathologica Communications
  • Seed amplification assay for the detection of pathologic alpha-synuclein aggregates in cerebrospinal fluid, 2023, Nature Protocols

The scientist collaborates frequently with several researchers, including:

  • Luis Concha-Marambio
  • Abhisek Mukherjee
  • Sandra Pritzkow
  • Inés Moreno-González
  • Mohammad Shahnawaz

Claudio Soto has also contributed to academic book literature. One such publication is:

  • Novel mechanisms involved in aging and neurodegeneration: Seeking potential therapeutic targets for neurodegenerative diseases., published by Frontiers Media in 2023

Best Publications

  • Unfolding the role of protein misfolding in neurodegenerative diseases.

    Claudio Soto

  • Sensitive detection of pathological prion protein by cyclic amplification of protein misfolding

    Gabriela P. Saborio;Bruno Permanne;Claudio Soto

  • Acetylcholinesterase Accelerates Assembly of Amyloid-β-Peptides into Alzheimer's Fibrils: Possible Role of the Peripheral Site of the Enzyme

    Nibaldo C. Inestrosa;Alejandra Alvarez;Cristián A. Pérez;Ricardo D. Moreno

  • Beta-sheet breaker peptides inhibit fibrillogenesis in a rat brain model of amyloidosis: implications for Alzheimer's therapy.

    C Soto;E M Sigurdsson;L Morelli;R A Kumar

  • Protein misfolding, aggregation, and conformational strains in neurodegenerative diseases

    Claudio Soto;Sandra Pritzkow

  • In Vitro Generation of Infectious Scrapie Prions

    Joaquín Castilla;Paula Saá;Paula Saá;Claudio Hetz;Claudio Hetz;Claudio Soto

  • Converting a peptide into a drug: strategies to improve stability and bioavailability.

    Celine Adessi;Claudio Soto

  • Discriminating α-synuclein strains in Parkinson’s disease and multiple system atrophy

    Mohammad Shahnawaz;Abhisek Mukherjee;Sandra Pritzkow;Nicolas Mendez

  • Bioaccumulation and toxicity of gold nanoparticles after repeated administration in mice.

    C. Lasagna-Reeves;D. Gonzalez-Romero;D. Gonzalez-Romero;M. A. Barria;M. A. Barria;I. Olmedo;I. Olmedo

  • Inhibition of Alzheimer's Amyloidosis by Peptides That Prevent β-Sheet Conformation

    Claudio Soto;Mark S. Kindy;Marc Baumann;Blas Frangione

  • An intracellular protein that binds amyloid-β peptide and mediates neurotoxicity in Alzheimer's disease

    Shi Du Yan;Jin Fu;Claudio Soto;Xi Chen

  • Caspase‐12 and endoplasmic reticulum stress mediate neurotoxicity of pathological prion protein

    Claudio Hetz;Milene Russelakis‐Carneiro;Kinsey Maundrell;Joaquin Castilla

  • Protein misfolding and disease; protein refolding and therapy.

    Claudio Soto

  • Development of a Biochemical Diagnosis of Parkinson Disease by Detection of α-Synuclein Misfolded Aggregates in Cerebrospinal Fluid

    Mohammad Shahnawaz;Takahiko Tokuda;Masaaki Waragai;Nicolas Mendez

  • Inhibition of Alzheimer β-Fibrillogenesis by Melatonin

    Miguel Pappolla;Peter Bozner;Claudio Soto;Haiyan Shao

  • Receptor-dependent cell stress and amyloid accumulation in systemic amyloidosis

    Shi Du Yan;Huaijie Zhu;Aiping Zhu;Adam Golabek

  • Production of cattle lacking prion protein.

    Jiirgen A. Richt;Poothappillai Kasinathan;Amir N. Hamir;Joaquin Castilla

  • Detection of prions in blood

    Joaquín Castilla;Paula Saá;Paula Saá;Claudio Soto

  • Protein misfolding and neurodegeneration.

    Claudio Soto;Lisbell D. Estrada;Lisbell D. Estrada

  • The alpha-helical to beta-strand transition in the amino-terminal fragment of the amyloid beta-peptide modulates amyloid formation.

    Claudio Soto;Eduardo M. Castaño;Blas Frangione;Nibaldo C. Inestrosa

  • Reversion of prion protein conformational changes by synthetic b-sheet breaker peptides

    Claudio Soto;Richard J Kascsak;Gabriela P Saborío;Pierre Aucouturier

Frequent Co-Authors

Claudio Hetz
Claudio Hetz University of Chile
Blas Frangione
Blas Frangione New York University
Thomas Wisniewski
Thomas Wisniewski New York University
William A. Banks
William A. Banks University of Washington
Fabrizio Tagliavini
Fabrizio Tagliavini Istituto Neurologico Carlo Besta
Pierluigi Gambetti
Pierluigi Gambetti Case Western Reserve University
Frances Prelli
Frances Prelli New York University
Felipe A. Court
Felipe A. Court Buck Institute for Research on Aging
Nibaldo C. Inestrosa
Nibaldo C. Inestrosa Pontificia Universidad Católica de Chile

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