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Neuroscience

D-Index
49
Citations
10489
World Ranking
5925
National Ranking
2600

Overview

Felipe A. Court is affiliated with the Buck Institute for Research on Aging in the United States. Their research primarily spans several interconnected fields, including Neuroscience, Medicine, and Biochemistry, Genetics and Molecular Biology. Within these domains, their work is particularly focused on Cellular and Molecular Neuroscience, Molecular Biology, Physiology, Neurology, and Cell Biology.

Their scientific contributions cover a variety of topics. Notable areas of study include nerve injury and regeneration, Alzheimer's disease research and treatments, RNA interference and gene delivery, neuroinflammation and neurodegeneration mechanisms, neuroscience and neuropharmacology research, endoplasmic reticulum stress and disease, and nuclear receptors and signaling.

Their frequent co-authors reflect ongoing collaborations and include Christian González-Billault, Alejandra Catenaccio, Patricia Lillo, Andrea Slachevsky, and Claudio Hetz.

Felipe A. Court has published extensively in several venues. Some of the frequently chosen journals and repositories for their work are bioRxiv (Cold Spring Harbor Laboratory), Neural Regeneration Research, Journal of Visualized Experiments, IBRO Neuroscience Reports, and Journal of Cell Science.

Among recent publications, notable papers include:

  • Schwann cell reprogramming into repair cells increases miRNA-21 expression in exosomes promoting axonal growth, 2020, Journal of Cell Science
  • Dementia in Latin America: Paving the way toward a regional action plan, 2020, Alzheimer s & Dementia
  • Axonal Degeneration in AD: The Contribution of Aβ and Tau, 2020, Frontiers in Aging Neuroscience
  • Insulin-like growth factor 2 (IGF2) protects against Huntington's disease through the extracellular disposal of protein aggregates, 2020, Acta Neuropathologica
  • Aβ oligomers trigger necroptosis-mediated neurodegeneration via microglia activation in Alzheimer's disease, 2022, Acta Neuropathologica Communications

Best Publications

  • Applying extracellular vesicles based therapeutics in clinical trials - an ISEV position paper

    Thomas Lener;Mario Gimona;Ludwig Aigner;Verena Börger

  • Wallerian degeneration of injured axons and synapses is delayed by a Ube4b/Nmnat chimeric gene.

    T G Mack;M Reiner;B Beirowski;W Mi

  • XBP-1 deficiency in the nervous system protects against amyotrophic lateral sclerosis by increasing autophagy

    Claudio Hetz;Peter Thielen;Soledad Matus;Melissa Nassif

  • Schwann cell-derived exosomes enhance axonal regeneration in the peripheral nervous system.

    María Alejandra Lopez-Verrilli;Frederic Picou;Felipe A. Court

  • Neurofascins are required to establish axonal domains for saltatory conduction.

    Diane L. Sherman;Steven Tait;Shona Melrose;Richard Johnson

  • Trehalose delays the progression of amyotrophic lateral sclerosis by enhancing autophagy in motoneurons.

    Karen Castillo;Melissa Nassif;Vicente Valenzuela;Fabiola Rojas

  • Emerging Roles of Extracellular Vesicles in the Nervous System

    Lawrence Rajendran;Jitin Bali;Maureen M. Barr;Felipe A. Court

  • Targeting the UPR transcription factor XBP1 protects against Huntington's disease through the regulation of FoxO1 and autophagy

    Rene L. Vidal;Alicia Figueroa;Felipe A. Court;Peter Thielen

  • Axonal Degeneration Is Mediated by the Mitochondrial Permeability Transition Pore

    Sebastian A. Barrientos;Nicolas W. Martinez;Soonmoon Yoo;Juan S. Jara

  • Schwann cell to axon transfer of ribosomes: toward a novel understanding of the role of glia in the nervous system.

    Felipe A Court;William T J Hendriks;Harold D MacGillavry;Jaime Alvarez

  • Control of dopaminergic neuron survival by the unfolded protein response transcription factor XBP1

    Pamela Valdés;Gabriela Mercado;Rene L. Vidal;Claudia Molina

  • β1 integrin activates Rac1 in Schwann cells to generate radial lamellae during axonal sorting and myelination

    Alessandro Nodari;Desirée Zambroni;Angelo Quattrini;Felipe A. Court

  • Restricted growth of Schwann cells lacking Cajal bands slows conduction in myelinated nerves

    Felipe A. Court;Diane L. Sherman;Thomas Pratt;Emer M. Garry

  • Progressive abnormalities in skeletal muscle and neuromuscular junctions of transgenic mice expressing the Huntington's disease mutation

    Richard R. Ribchester;Derek Thomson;Nigel I. Wood;Tim Hinks

  • Calcium release from intra-axonal endoplasmic reticulum leads to axon degeneration through mitochondrial dysfunction.

    Rosario Villegas;Nicolas W. Martinez;Jorge Lillo;Phillipe Pihan

  • Mitochondria as a central sensor for axonal degenerative stimuli

    Felipe A. Court;Michael P. Coleman

  • Axonal Degeneration during Aging and Its Functional Role in Neurodegenerative Disorders.

    Natalia Salvadores;Mario Sanhueza;Patricio Manque;Felipe A. Court

  • Activation of the unfolded protein response enhances motor recovery after spinal cord injury

    V. Valenzuela;E. Collyer;D. Armentano;G. B. Parsons

  • IRE1α governs cytoskeleton remodelling and cell migration through a direct interaction with filamin A

    Hery Urra;Daniel R Henriquez;José Cánovas;David Villarroel-Campos

  • Schwann Cell Exosomes Mediate Neuron–Glia Communication and Enhance Axonal Regeneration

    Rodrigo Lopez-Leal;Felipe A Court

  • BAX inhibitor-1 regulates autophagy by controlling the IRE1α branch of the unfolded protein response.

    Karen Castillo;Diego Rojas-Rivera;Fernanda Lisbona;Benjamín Caballero

  • Measurement of autophagy flux in the nervous system in vivo

    K Castillo;V Valenzuela;S Matus;M Nassif

  • Morphological evidence for a transport of ribosomes from Schwann cells to regenerating axons

    Felipe A. Court;Rajiv Midha;Bruno A. Cisterna;Joey Grochmal

Frequent Co-Authors

Richard R. Ribchester
Richard R. Ribchester University of Edinburgh
Claudio Soto
Claudio Soto The University of Texas Health Science Center at Houston
Peter J. Brophy
Peter J. Brophy University of Edinburgh
Mario A. Parra
Mario A. Parra University of Strathclyde
Ludwig Aigner
Ludwig Aigner Paracelsus Medical University
Nibaldo C. Inestrosa
Nibaldo C. Inestrosa Pontificia Universidad Católica de Chile
Michael P. Coleman
Michael P. Coleman University of Cambridge
Agustín Ibáñez
Agustín Ibáñez Adolfo Ibáñez University
Ana Maria Cuervo
Ana Maria Cuervo Albert Einstein College of Medicine

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