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Microbiology

D-Index
67
Citations
19610
World Ranking
2246
National Ranking
77

Overview

Amanda J. Leach is affiliated with Charles Darwin University in Australia. Their research primarily spans the field of Medicine with a focus on epidemiology, pulmonary and respiratory medicine, otorhinolaryngology, infectious diseases, and microbiology. Their body of work includes 179 publications categorized under Medicine.

They have contributed significantly to the study of respiratory viral infections, pneumonia, neonatal respiratory health, and infections related to ear and airway conditions. The main topics addressed in their research include:

  • Respiratory viral infections research
  • Pneumonia and Respiratory Infections
  • Ear Surgery and Otitis Media
  • Neonatal Respiratory Health Research
  • Bacterial Infections and Vaccines
  • Viral gastroenteritis research and epidemiology
  • Tracheal and airway disorders

Leach has frequently published in several venues, evidencing a consistent presence in journals focused on infectious diseases and pediatric specialties. The publication venues with multiple contributions include:

  • The Journal of Infectious Diseases
  • Open Forum Infectious Diseases
  • Journal of the Pediatric Infectious Diseases Society
  • International Journal of Pediatric Otorhinolaryngology
  • The Lancet Child & Adolescent Health

Recently, Leach has been associated with notable papers addressing respiratory syncytial virus (RSV) and the preventative agent nirsevimab. These papers include:

  • Efficacy of nirsevimab against respiratory syncytial virus lower respiratory tract infections in preterm and term infants, and pharmacokinetic extrapolation to infants with congenital heart disease and chronic lung disease: a pooled analysis of randomised controlled trials, 2023, The Lancet Child & Adolescent Health
  • Nirsevimab for Prevention of RSV in Term and Late-Preterm Infants, 2023, New England Journal of Medicine
  • Safety of Nirsevimab for RSV in Infants with Heart or Lung Disease or Prematurity, 2022, New England Journal of Medicine
  • Durability of neutralizing RSV antibodies following nirsevimab administration and elicitation of the natural immune response to RSV infection in infants, 2023, Nature Medicine
  • Respiratory Syncytial Virus-Associated Hospital Admissions in Children Younger Than 5 Years in 7 European Countries Using Routinely Collected Datasets, 2020, The Journal of Infectious Diseases

They have collaborated extensively with various researchers, including:

  • Andrew J. Pollard
  • Harish Nair
  • Terho Heikkinen
  • Harry Campbell
  • Peter Openshaw

Best Publications

  • Single-dose administration and the influence of the timing of the booster dose on immunogenicity and efficacy of ChAdOx1 nCoV-19 (AZD1222) vaccine: a pooled analysis of four randomised trials.

    M Voysey;S A Costa Clemens;S A Madhi;L Y Weckx

  • First results of phase 3 trial of RTS,S/AS01 malaria vaccine in African children.

    Selidji Todagbe Agnandji;Bertrand Lell;Bertrand Lell;Solange Solmeheim Soulanoudjingar;Solange Solmeheim Soulanoudjingar

  • Efficacy of nine-valent pneumococcal conjugate vaccine against pneumonia and invasive pneumococcal disease in The Gambia: randomised, double-blind, placebo-controlled trial

    F. T. Cutts;S. M. A. Zaman;G. Enwere;S. Jaffar

  • Efficacy of the RTS,S/AS02A vaccine against Plasmodium falciparum infection and disease in young African children: randomised controlled trial

    Pedro L. Alonso;Jahit Sacarlal;John J. Aponte;Amanda J Leach

  • A phase 3 trial of RTS,S/AS01 malaria vaccine in African infants.

    Selidji Todagbe Agnandji;Selidji Todagbe Agnandji;Bertrand Lell;Bertrand Lell;José Francisco Fernandes;José Francisco Fernandes

  • Duration of protection with RTS,S/AS02A malaria vaccine in prevention of Plasmodium falciparum disease in Mozambican children: single-blind extended follow-up of a randomised controlled trial

    Pedro L Alonso;Jahit Sacarlal;John J Aponte;Amanda Leach

  • Efficacy of RTS,S/AS01E Vaccine against Malaria in Children 5 to 17 Months of Age

    Philip Bejon;John Lusingu;Ally Olotu;Amanda Leach

  • Standard method for detecting upper respiratory carriage of Streptococcus pneumoniae: updated recommendations from the World Health Organization Pneumococcal Carriage Working Group.

    Catherine Satzke;Catherine Satzke;Paul Turner;Paul Turner;Anni Virolainen-Julkunen;Peter V. Adrian

  • Seven-Year Efficacy of RTS,S/AS01 Malaria Vaccine among Young African Children

    Ally Olotu;Gregory Fegan;Juliana Wambua;George Nyangweso

  • Global Disease Burden Estimates of Respiratory Syncytial Virus-Associated Acute Respiratory Infection in Older Adults in 2015: A Systematic Review and Meta-Analysis.

    Ting Shi;Angeline Denouel;Anna K Tietjen;Iain Campbell

  • Genetic Diversity and Protective Efficacy of the RTS,S/AS01 Malaria Vaccine

    Daniel E Neafsey;Michal Juraska;Trevor Bedford;David Benkeser

  • Bacterial colonization of the nasopharynx predicts very early onset and persistence of otitis media in Australian aboriginal infants.

    Amanda J. Leach;Judith B. Boswell;Valerie Asche;Terry G. Nienhuys

  • Blood stage malaria vaccine eliciting high antigen-specific antibody concentrations confers no protection to young children in Western Kenya.

    Bernhards R. Ogutu;Odika J. Apollo;Denise McKinney;Willis Okoth

  • Four-Year Efficacy of RTS,S/AS01E and Its Interaction with Malaria Exposure

    Ally Olotu;Gregory Fegan;Juliana Wambua;George Nyangweso

  • Safety of the RTS,S/AS02D candidate malaria vaccine in infants living in a highly endemic area of Mozambique: a double blind randomised controlled phase I/IIb trial

    John J Aponte;John J Aponte;Pedro Aide;Montse Renom;Montse Renom;Inacio Mandomando

  • From the circumsporozoite protein to the RTS, S/AS candidate vaccine.

    Joe Cohen;Victor Nussenzweig;Ruth Nussenzweig;Johan Vekemans

  • Safety and Immunogenicity of RTS,S/AS02D Malaria Vaccine in Infants

    Salim Abdulla;Rolf Oberholzer;Rolf Oberholzer;Omar Juma;Sulende Kubhoja

  • A prospective study of the impact of community-based azithromycin treatment of trachoma on carriage and resistance of Streptococcus pneumoniae.

    Amanda J. Leach;Tania M. Shelby-James;Mark Mayo;Mike Gratten

  • Towards an RTS,S-based, multi-stage, multi-antigen vaccine against falciparum malaria: progress at the Walter Reed Army Institute of Research.

    D. Gray Heppner;Kent E. Kester;Christian F. Ockenhouse;Nadia Tornieporth

  • Efficacy trial of malaria vaccine SPf66 in Gambian infants

    U. D'Alessandro;A. Leach;B.O. Olaleye;G.W. Fegan

Frequent Co-Authors

Anne B. Chang
Anne B. Chang Boston Children's Hospital
Joe Cohen
Joe Cohen GlaxoSmithKline (United Kingdom)
Keith Grimwood
Keith Grimwood Griffith University
W. Ripley Ballou
W. Ripley Ballou International AIDS Vaccine Initiative
Jonathan R. Carapetis
Jonathan R. Carapetis Telethon Kids Institute
Philip Bejon
Philip Bejon University of Oxford
Pedro L. Alonso
Pedro L. Alonso University of Barcelona
Marcel Tanner
Marcel Tanner Swiss Tropical and Public Health Institute
Kevin Marsh
Kevin Marsh University of Oxford
Allen C. Cheng
Allen C. Cheng Monash University

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