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Research.com Recognitions

  • 2011 - Fellow of the Royal Society of Edinburgh

Overview

James W. Ironside is affiliated with the University of Edinburgh in the United Kingdom. Their research spans the areas of medicine and biochemistry, genetics, and molecular biology, with a particular focus on neurology and molecular biology. Subfields of study include hematology, nutrition and dietetics, and physiology.

The scientist's work primarily addresses topics such as prion diseases and protein misfolding, neurological diseases and metabolism, trace elements in health, Alzheimer's disease research and treatments, Parkinson's disease mechanisms and treatments, intracerebral and subarachnoid hemorrhage research, as well as neurosurgical procedures and complications.

James W. Ironside has contributed to a variety of research papers, with recent publications including:

  • "Serpin Signatures in Prion and Alzheimer's Diseases," 2022, published in Molecular Neurobiology
  • "Prevalence in Britain of abnormal prion protein in human appendices before and after exposure to the cattle BSE epizootic," 2020, published in Acta Neuropathologica
  • "Prions from Sporadic Creutzfeldt-Jakob Disease Patients Propagate as Strain Mixtures," 2020, published in mBio
  • "Wide distribution of prion infectivity in the peripheral tissues of vCJD and sCJD patients," 2021, published in Acta Neuropathologica
  • "Fulminant corticobasal degeneration: a distinct variant with predominant neuronal tau aggregates," 2020, published in Acta Neuropathologica

The most frequent publication venues for this scientist include the journals Acta Neuropathologica, Molecular Neurobiology, mBio, International Journal of Stroke, and Acta Neuropathologica Communications.

James W. Ironside collaborates regularly with several co-authors, notably Hervé Cassard, Alvina Huor, Jean-Yves Douet, Séverine Lugan, and Naïma Aron.

In recognition of their contributions to science, they were made a Fellow of the Royal Society of Edinburgh in 2011.

Best Publications

  • A new variant of Creutzfeldt-Jakob disease in the UK

    R G Will;J W Ironside;M Zeidler;S N Cousens

  • Transmissions to mice indicate that ‘new variant’ CJD is caused by the BSE agent

    M. E. Bruce;R. G. Will;J. W. Ironside;I. McConnell

  • Molecular analysis of prion strain variation and the aetiology of 'new variant' CJD

    John Collinge;John Collinge;Katie C. L. Sidle;Julie Meads;James Ironside

  • Investigation of variant Creutzfeldt-Jakob disease and other human prion diseases with tonsil biopsy samples

    AF Hill;RJ Butterworth;S Joiner;G Jackson

  • Compelling transgenetic evidence for transmission of bovine spongiform encephalopathy prions to humans.

    Michael R. Scott;Robert Will;James Ironside;Hoang-Oanh B. Nguyen

  • Preclinical variant CJD after blood transfusion in a PRNP codon 129 heterozygous patient

    Alexander Peden;Mark Head;Diane Ritchie;Jeanne Bell

  • Florbetaben PET imaging to detect amyloid beta plaques in Alzheimer's disease: Phase 3 study

    Osama Sabri;Marwan N. Sabbagh;John Seibyl;Henryk Barthel

  • Alpha‐synuclein RT‐QuIC in the CSF of patients with alpha‐synucleinopathies

    Graham Fairfoul;Lynne I McGuire;Suvankar Pal;James W Ironside

  • Diagnosis of new variant Creutzfeldt-Jakob disease by tonsil biopsy

    Andrew F Hill;Martin Zeidler;James Ironside;John Collinge

  • BSE transmission to macaques

    C I Lasmézas;J P Deslys;R Demaimay;K T Adjou

  • Prevalence of lymphoreticular prion protein accumulation in UK tissue samples.

    David A Hilton;Azra C Ghani;Lisa Conyers;Philip Edwards

  • Neuropathological Diagnostic-criteria for Creutzfeldt-jakob-disease (cjd) and Other Human Spongiform Encephalopathies (prion Diseases)

    Herbert Budka;Adriano Aguzzi;Paul Brown;Jean-Marie Brucher

  • Diagnosis of new variant Creutzfeldt-Jakob disease.

    R. G. Will;M. Zeidler;G. E. Stewart;M. A. Macleod

  • Aging-related tau astrogliopathy (ARTAG): harmonized evaluation strategy

    Gabor G. Kovacs;Isidro Ferrer;Lea T. Grinberg;Lea T. Grinberg;Irina Alafuzoff

  • Prion immunoreactivity in appendix before clinical onset of variant Creutzfeldt-Jakob disease

    David A Hilton;Edward Fathers;Philip Edwards;James W Ironside

  • The pulvinar sign on magnetic resonance imaging in variant Creutzfeldt-Jakob disease.

    Martin Zeidler;Robin J Sellar;Donald A Collie;Richard Knight

  • Results of a Randomized Study of Preradiation Chemotherapy Versus Radiotherapy Alone for Nonmetastatic Medulloblastoma: The International Society of Paediatric Oncology/United Kingdom Children’s Cancer Study Group PNET-3 Study

    Roger E. Taylor;Clifford C. Bailey;Kath Robinson;Claire L. Weston

  • Molecular classification of sporadic Creutzfeldt-Jakob disease.

    Andrew F. Hill;Susan Joiner;Jonathan D. F. Wadsworth;Katie C. L. Sidle

  • Reversion of prion protein conformational changes by synthetic b-sheet breaker peptides

    Claudio Soto;Richard J Kascsak;Gabriela P Saborío;Pierre Aucouturier

  • Predicting susceptibility and incubation time of human-to-human transmission of vCJD

    Matthew T Bishop;P Hart;L Aitchison;Herbert N Baybutt

Frequent Co-Authors

Mark Head
Mark Head University of Edinburgh
Robert G. Will
Robert G. Will University of Edinburgh
Jean Manson
Jean Manson University of Edinburgh
Jeanne E. Bell
Jeanne E. Bell University of Edinburgh
Herbert Budka
Herbert Budka Medical University of Vienna
Gabor G. Kovacs
Gabor G. Kovacs University of Toronto
Peter L. Lantos
Peter L. Lantos King's College London
Colin Smith
Colin Smith University of Edinburgh
Bernardino Ghetti
Bernardino Ghetti Indiana University
Fabrizio Tagliavini
Fabrizio Tagliavini Istituto Neurologico Carlo Besta

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