World's Best Scientists 2026 revealed!

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Immunology

D-Index
88
Citations
25600
World Ranking
1177
National Ranking
622

Medicine

D-Index
88
Citations
25600
World Ranking
13263
National Ranking
6757

Research.com Recognitions

  • 2016 - Fellow of the American Association for the Advancement of Science (AAAS)

Overview

Phillip Scott is affiliated with the University of Pennsylvania in the United States. Their research spans multiple fields of medicine with a strong emphasis on immunology and microbiology, reflected in over a hundred publications. Primary areas of study include public health, environmental and occupational health, immunology, epidemiology, rheumatology, and rehabilitation.

Their scientific contributions focus on several main topics: research related to Leishmaniasis studies, acute ischemic stroke management, urticaria and related conditions, Trypanosoma species research and implications, toxin mechanisms and immunotoxins, stroke rehabilitation and recovery, and parasites and host interactions.

Phillip Scott's recent notable papers include:

  • Host-Directed Therapies for Cutaneous Leishmaniasis, 2021, Frontiers in Immunology
  • Granzyme B Inhibition by Tofacitinib Blocks the Pathology Induced by CD8 T Cells in Cutaneous Leishmaniasis, 2020, Journal of Investigative Dermatology
  • Localized skin inflammation during cutaneous leishmaniasis drives a chronic, systemic IFN-γ signature, 2021, PLoS Neglected Tropical Diseases
  • Multiomic profiling of cutaneous leishmaniasis infections reveals microbiota-driven mechanisms underlying disease severity, 2023, Science Translational Medicine
  • Microbiota instruct IL-17A-producing innate lymphoid cells to promote skin inflammation in cutaneous leishmaniasis, 2021, PLoS Pathogens

Frequent co-authors collaborating with Phillip Scott include:

  • Lucas P. Carvalho
  • Camila Farias Amorim
  • Edgar M. Carvalho
  • Daniel P. Beiting
  • Fernanda O. Novais

The most common venues for their publications are:

  • The Journal of Immunology
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Stroke
  • PLoS Pathogens
  • Heart Lung and Circulation

Phillip Scott has been recognized as a Fellow of the American Association for the Advancement of Science (AAAS) since 2016.

Best Publications

  • Leishmaniasis: complexity at the host–pathogen interface

    Paul Kaye;Phillip Scott

  • Immunoregulation of cutaneous leishmaniasis. T cell lines that transfer protective immunity or exacerbation belong to different T helper subsets and respond to distinct parasite antigens.

    P Scott;P Natovitz;R L Coffman;E Pearce

  • The adjuvant effect of interleukin-12 in a vaccine against Leishmania major

    Luis C. C. Afonso;Tanya M. Scharton;Leda Q. Vieira;Maria Wysocka

  • Natural killer cells are a source of interferon gamma that drives differentiation of CD4+ T cell subsets and induces early resistance to Leishmania major in mice.

    T M Scharton;P Scott

  • IL-12: initiation cytokine for cell-mediated immunity.

    Phillip Scott

  • IFN-gamma modulates the early development of Th1 and Th2 responses in a murine model of cutaneous leishmaniasis.

    P Scott

  • Cutaneous leishmaniasis: immune responses in protection and pathogenesis

    Phillip Scott;Fernanda O. Novais

  • INTERLEUKIN-12 IS REQUIRED FOR INTERFERON-GAMMA PRODUCTION AND LETHALITY IN LIPOPOLYSACCHARIDE-INDUCED SHOCK IN MICE

    Maria Wysocka;Marek Kubin;Leda Q. Vieira;Leda Q. Vieira;Laurence Ozmen;Laurence Ozmen

  • IL-12 is required for natural killer cell activation and subsequent T helper 1 cell development in experimental leishmaniasis.

    T. Scharton-Kersten;L. C. C. Afonso;M. Wysocka;G. Trinchieri

  • Role of cytokines and CD4+ T-cell subsets in the regulation of parasite immunity and disease

    Phillip Scott;Edward Pearce;Allen W. Cheever;Robert L. Coffman

  • The role of T-cell subsets and cytokines in the regulation of infection

    Phillip Scott;Stefan H.E. Kaufmann

  • Central memory T cells mediate long-term immunity to Leishmania major in the absence of persistent parasites

    Colby Zaph;Jude Uzonna;Stephen M Beverley;Phillip Scott

  • RELMβ/FIZZ2 is a goblet cell-specific immune-effector molecule in the gastrointestinal tract

    David Artis;Mei Lun Wang;Sue A. Keilbaugh;Weimian He

  • Helper T-cell subsets in mouse leishmaniasis: induction, expansion and effector function

    Richard M. Locksley;Phillip Scott

  • Role of cytokines in the differentiation of CD4+ T-cell subsets in vivo.

    Robert L. Coffman;Kari Varkila;Phillip Scott;René Chatelain

  • Immune responses associated with susceptibility of C57BL/10 mice to Leishmania amazonensis.

    L. C. C. Afonso;P. Scott

  • TRAF6 is a critical factor for dendritic cell maturation and development.

    Takashi Kobayashi;Patrick T Walsh;Matthew C Walsh;Kendra M Speirs

  • The IL-27 Receptor (WSX-1) Is an Inhibitor of Innate and Adaptive Elements of Type 2 Immunity

    David Artis;Alejandro Villarino;Michael Silverman;Weimian He

  • Interleukin 5 is required for the blood and tissue eosinophilia but not granuloma formation induced by infection with Schistosoma mansoni.

    Alan Sher;Robert L. Coffman;Sara Hieny;Phillip Scott

  • Vaccination against cutaneous leishmaniasis in a murine model. I. Induction of protective immunity with a soluble extract of promastigotes.

    P Scott;E Pearce;P Natovitz;A Sher

Frequent Co-Authors

Edgar M. Carvalho
Edgar M. Carvalho Federal University of Bahia
David Artis
David Artis Cornell University
Christopher A. Hunter
Christopher A. Hunter University of Pennsylvania
Giorgio Trinchieri
Giorgio Trinchieri National Institutes of Health
Edward J. Pearce
Edward J. Pearce Johns Hopkins University
Maria Wysocka
Maria Wysocka University of Pennsylvania
Jorge Caamano
Jorge Caamano University of Birmingham
David M. Mosser
David M. Mosser University of Maryland, College Park
David Abraham
David Abraham University College London
David S. Roos
David S. Roos University of Pennsylvania

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