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Biology and Biochemistry

D-Index
58
Citations
12784
World Ranking
13128
National Ranking
495

Overview

Anne Galy is affiliated with Inserm, the Institut national de la santé et de la recherche médicale in France. Their research spans several fields related to biomedicine, particularly focusing on genetics and molecular biology as well as medicine. The subfields of study include genetics, molecular biology, oncology, immunology, and hematology.

Their main research topics cover virus-based gene therapy, CAR-T cell therapy, CRISPR and genetic engineering, viral infectious diseases and gene expression in insects, retinal development and disorders, cellular mechanics and interactions, and hematopoietic stem cell transplantation.

Several recent publications authored or co-authored by Anne Galy reflect these interests. Some notable papers include:

  • Lentiviral gene therapy for X-linked chronic granulomatous disease, 2020, Nature Medicine
  • Long-term safety and efficacy of lentiviral hematopoietic stem/progenitor cell gene therapy for Wiskott-Aldrich syndrome, 2022, Nature Medicine
  • Clonal tracking in gene therapy patients reveals a diversity of human hematopoietic differentiation programs, 2020, Blood
  • Time to evolve: predicting engineered T cell-associated toxicity with next-generation models, 2022, Journal for ImmunoTherapy of Cancer
  • Outcomes of hematopoietic stem cell gene therapy for Wiskott-Aldrich syndrome, 2023, Blood

Anne Galy has frequently published in prominent scientific journals, including a significant number of papers in Blood, Molecular Therapy - Methods & Clinical Development, Bone Marrow Transplantation, Nature Medicine, and Human Gene Therapy.

Collaboration plays an important role in their work. Frequent co-authors include Marina Cavazzana, Adrian J. Thrasher, Emma Morris, Frederic D. Bushman, and Cécile Roudaut. These collaborations indicate a focus on gene therapy and related translational research.

Best Publications

  • Lentiviral Hematopoietic Stem Cell Gene Therapy in Patients with Wiskott-Aldrich Syndrome

    Alessandro Aiuti;Luca Biasco;Samantha Scaramuzza;Francesca Ferrua

  • Pax7-expressing satellite cells are indispensable for adult skeletal muscle regeneration.

    Ramkumar Sambasivan;Roseline Yao;Adrien Kissenpfennig;Laetitia Van Wittenberghe

  • Human T, B, natural killer, and dendritic cells arise from a common bone marrow progenitor cell subset.

    Anne Galy;Marilyn Travis;Dazhi Cen;Benjamin Chen

  • Insertional Transformation of Hematopoietic Cells by Self-inactivating Lentiviral and Gammaretroviral Vectors

    Ute Modlich;Susana Navarro;Daniela Zychlinski;Tobias Maetzig

  • Outcomes Following Gene Therapy in Patients With Severe Wiskott-Aldrich Syndrome

    Salima Hacein-Bey Abina;H. Bobby Gaspar;Johanna Blondeau;Laure Caccavelli

  • NK cell activation by dendritic cells (DCs) requires the formation of a synapse leading to IL-12 polarization in DCs

    Christophe Borg;Abdelali Jalil;Diego Laderach;Kouji Maruyama

  • CD40 is functionally expressed on human thymic epithelial cells.

    A. H. M. Galy;H. Spits

  • Gene therapy on the move

    Kerstin B. Kaufmann;Hildegard Büning;Anne Galy;Axel Schambach;Axel Schambach

  • An essential role for tripeptidyl peptidase in the generation of an MHC class I epitope.

    Ulrike Seifert;Concepcion Maranon;Ayelet Shmueli;Jean-Francois Desoutter

  • Enrichment of human hematopoietic stem cell activity in the CD34+Thy-1+Lin- subpopulation from mobilized peripheral blood.

    L Murray;B Chen;A Galy;S Chen

  • Lentiviral gene therapy for X-linked chronic granulomatous disease.

    Donald B. Kohn;Claire Booth;Elizabeth M. Kang;Sung-Yun Pai

  • Large-Scale Manufacture and Characterization of a Lentiviral Vector Produced for Clinical Ex Vivo Gene Therapy Application

    Otto Wilhelm Merten;Sabine Charrier;Nicolas Laroudie;Sylvain Fauchille

  • Precursors of CD3+CD4+CD8+ cells in the human thymus are defined by expression of CD34. Delineation of early events in human thymic development.

    A. Galy;Sunita Verma;A. Barcena;H. Spits

  • IL-1β induces dendritic cells to produce IL-12

    Amy K. Wesa;Anne Galy

  • Human fetal bone marrow early progenitors for T, B, and myeloid cells are found exclusively in the population expressing high levels of CD34

    David DiGiusto;Shirley Chen;Jesse Combs;Saiphone Webb

  • 4‐1BB co‐stimulation enhances human CD8+ T cell priming by augmenting the proliferation and survival of effector CD8+ T cells

    Diego Laderach;Mojgan Movassagh;Anthony Johnson;Robert S. Mittler

  • GPL, a Novel Cytokine Receptor Related to GP130 and Leukemia Inhibitory Factor Receptor *

    Caroline Diveu;Eric Lelièvre;David Perret;Anne-Hélène Lagrue Lak-Hal

  • Protection against mammary tumor growth by vaccination with full-length, modified human ErbB-2 DNA.

    Wei Zen Wei;Wei Ping Shi;Anne Galy;Darcy Lichlyter

  • Successful engraftment of gene-corrected hematopoietic stem cells in non-conditioned patients with Fanconi anemia.

    Paula Río;Susana Navarro;Wei Wang;Rebeca Sánchez-Domínguez

  • Dendritic Cells Generated Either from CD34+ Progenitor Cells or from Monocytes Differ in Their Ability to Activate Antigen-Specific CD8+ T Cells

    Guido Ferlazzo;Amy Wesa;Wei Zen Wei;Anne Galy

Frequent Co-Authors

Adrian J. Thrasher
Adrian J. Thrasher University College London
William Vainchenker
William Vainchenker Institut Gustave Roussy
Maria Grazia Roncarolo
Maria Grazia Roncarolo Stanford University
Luigi Naldini
Luigi Naldini Vita-Salute San Raffaele University
Alessandro Aiuti
Alessandro Aiuti Vita-Salute San Raffaele University
José-Alain Sahel
José-Alain Sahel University of Pittsburgh
Burkhard Bechinger
Burkhard Bechinger University of Strasbourg
Olivier Danos
Olivier Danos REGENXBIO Inc.
Najet Debili
Najet Debili Institut Gustave Roussy
Frederic D. Bushman
Frederic D. Bushman University of Pennsylvania

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