D-Index & Metrics Best Publications
Research.com 2022 Best Female Scientist Award Badge

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Best female scientists D-index 105 Citations 50,300 408 World Ranking 698 National Ranking 434
Immunology D-index 106 Citations 51,194 383 World Ranking 317 National Ranking 199
Medicine D-index 106 Citations 51,608 401 World Ranking 3759 National Ranking 2134

Research.com Recognitions

Awards & Achievements

2022 - Research.com Best Female Scientist Award

2005 - Member of Academia Europaea

Overview

What is she best known for?

The fields of study she is best known for:

  • Immune system
  • Gene
  • Internal medicine

Her primary areas of investigation include Immunology, Cell biology, IL-2 receptor, Interleukin 10 and FOXP3. Her Immunology research includes elements of Hematopoietic stem cell transplantation and Genetic enhancement. Her Cell biology research is multidisciplinary, incorporating elements of Acquired immune system, CD28, Growth factor and CD40.

Her work carried out in the field of IL-2 receptor brings together such families of science as Peripheral tolerance, Clonal deletion, Natural killer T cell and Suppressor. Her research in Interleukin 10 intersects with topics in Open reading frame, Anticorps monoclonal, Cellular differentiation and Antigen. Her work in Antigen-presenting cell addresses issues such as Interleukin 21, which are connected to fields such as Molecular biology and Interferon gamma.

Her most cited work include:

  • A CD4 + T-cell subset inhibits antigen-specific T-cell responses and prevents colitis (3394 citations)
  • Interleukin-10-secreting type 1 regulatory T cells in rodents and humans. (1052 citations)
  • Correction of ADA-SCID by Stem Cell Gene Therapy Combined with Nonmyeloablative Conditioning (1013 citations)

What are the main themes of her work throughout her whole career to date?

Her scientific interests lie mostly in Immunology, Immune system, T cell, Cell biology and Transplantation. Her Immunology study combines topics in areas such as Stem cell and Genetic enhancement. Her Immune system research incorporates elements of Transgene, Cell therapy and Antigen.

Maria Grazia Roncarolo interconnects Cytotoxic T cell, CD8 and Molecular biology in the investigation of issues within T cell. Her Cell biology study deals with In vitro intersecting with In vivo. Her IL-2 receptor research includes elements of Peripheral tolerance and Antigen-presenting cell.

She most often published in these fields:

  • Immunology (59.66%)
  • Immune system (21.26%)
  • T cell (21.26%)

What were the highlights of her more recent work (between 2014-2021)?

  • Immunology (59.66%)
  • Immune system (21.26%)
  • FOXP3 (16.18%)

In recent papers she was focusing on the following fields of study:

Maria Grazia Roncarolo mainly focuses on Immunology, Immune system, FOXP3, Hematopoietic stem cell transplantation and Transplantation. Her study in Humanized mouse, Interleukin 21, Regulatory T cell and Flow cytometry is carried out as part of her studies in Immunology. As part of one scientific family, Maria Grazia Roncarolo deals mainly with the area of Immune system, narrowing it down to issues related to the Cell therapy, and often Immune tolerance and Granzyme.

Maria Grazia Roncarolo has included themes like Immune dysregulation, Antigen, IPEX syndrome, NOD mice and Cell biology in her FOXP3 study. Her Hematopoietic stem cell transplantation research integrates issues from Myeloid, Bone marrow and B cell. Her studies deal with areas such as Cancer research, Immunosuppression, Stem cell, Hematopoietic stem cell and Severe combined immunodeficiency as well as Transplantation.

Between 2014 and 2021, her most popular works were:

  • Reprogramming human T cell function and specificity with non-viral genome targeting (346 citations)
  • Lentiviral haemopoietic stem-cell gene therapy in early-onset metachromatic leukodystrophy: an ad-hoc analysis of a non-randomised, open-label, phase 1/2 trial (245 citations)
  • From IPEX syndrome to FOXP3 mutation: a lesson on immune dysregulation (166 citations)

In her most recent research, the most cited papers focused on:

  • Immune system
  • Gene
  • Internal medicine

The scientist’s investigation covers issues in Immunology, Hematopoietic stem cell transplantation, FOXP3, Immune system and Cell biology. Her Immunology study integrates concerns from other disciplines, such as Viral vector and Genetic enhancement. As a member of one scientific family, she mostly works in the field of Hematopoietic stem cell transplantation, focusing on Hematopoietic stem cell and, on occasion, Oncology.

Her research in FOXP3 intersects with topics in Immune dysregulation and IL-2 receptor. The various areas that Maria Grazia Roncarolo examines in her Immune system study include Clinical trial and In vivo. Maria Grazia Roncarolo combines subjects such as T cell, Antigen and Single-cell analysis with her study of Cell biology.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

A CD4 + T-cell subset inhibits antigen-specific T-cell responses and prevents colitis

Hervé Groux;Anne O'Garra;Mike Bigler;Matthieu Rouleau.
Nature (1997)

4586 Citations

Rapamycin selectively expands CD4+CD25+FoxP3+ regulatory T cells

Manuela Battaglia;Angela Stabilini;Maria Grazia Roncarolo.
Blood (2005)

1568 Citations

Interleukin-10-secreting type 1 regulatory T cells in rodents and humans.

Maria Grazia Roncarolo;Silvia Gregori;Manuela Battaglia;Rosa Bacchetta.
Immunological Reviews (2006)

1519 Citations

Correction of ADA-SCID by Stem Cell Gene Therapy Combined with Nonmyeloablative Conditioning

Alessandro Aiuti;Shimon Slavin;Memet Aker;Francesca Ficara.
Science (2002)

1378 Citations

Human Cd25+Cd4+ T Regulatory Cells Suppress Naive and Memory T Cell Proliferation and Can Be Expanded in Vitro without Loss of Function

Megan K. Levings;Romina Sangregorio;Maria Grazia Roncarolo.
Journal of Experimental Medicine (2001)

1306 Citations

Lentiviral hematopoietic stem cell gene therapy benefits metachromatic leukodystrophy.

Alessandra Biffi;Eugenio Montini;Laura Lorioli;Martina Cesani.
Science (2013)

1201 Citations

Interleukin-10 induces a long-term antigen-specific anergic state in human CD4+ T cells.

H Groux;M Bigler;J E de Vries;M G Roncarolo.
Journal of Experimental Medicine (1996)

1165 Citations

Type 1 T regulatory cells.

Maria Grazia Roncarolo;Rosa Bacchetta;Claudio Bordignon;Satwant Narula.
Immunological Reviews (2001)

1142 Citations

Isolation and expression of human cytokine synthesis inhibitory factor cDNA clones: homology to Epstein-Barr virus open reading frame BCRFI.

P Vieira;R de Waal-Malefyt;M N Dang;K E Johnson.
Proceedings of the National Academy of Sciences of the United States of America (1991)

1137 Citations

Lentiviral Hematopoietic Stem Cell Gene Therapy in Patients with Wiskott-Aldrich Syndrome

Alessandro Aiuti;Luca Biasco;Samantha Scaramuzza;Francesca Ferrua.
Science (2013)

1088 Citations

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