World's Best Scientists 2026 revealed!
Maria Grazia Roncarolo

Maria Grazia Roncarolo

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Best Female Scientists
2025

D-Index & Metrics

Best Female Scientists

D-Index
113
Citations
61445
World Ranking
760
National Ranking
462

Immunology

D-Index
116
Citations
63144
World Ranking
373
National Ranking
235

Medicine

D-Index
116
Citations
63166
World Ranking
4294
National Ranking
2346

Research.com Recognitions

  • 2025 - Research.com Best Female Scientists Award
  • 2005 - Member of Academia Europaea

Overview

Maria Grazia Roncarolo is affiliated with Stanford University in the United States. Their research spans multiple disciplines with a primary focus on Medicine, Immunology and Microbiology, and Biochemistry, Genetics and Molecular Biology. The specific subfields of study include Immunology, Molecular Biology, Oncology, Hematology, and Genetics.

Their work covers a broad range of topics, notably:

  • Immune Cell Function and Interaction
  • T-cell and B-cell Immunology
  • CAR-T cell therapy research
  • Hematopoietic Stem Cell Transplantation
  • CRISPR and Genetic Engineering
  • Virus-based gene therapy research
  • DNA Repair Mechanisms

Roncarolo's publication record includes contributions to prominent journals with the highest number of publications found in Blood and Transplantation and Cellular Therapy, followed by Frontiers in Immunology, bioRxiv (Cold Spring Harbor Laboratory), and Science Translational Medicine.

Frequent collaborators in their research include Rosa Bacchetta, Alice Bertaina, Rajni Agarwal, Alma-Martina Cepika, and Agnieszka Czechowicz.

Representative recent papers illustrate the scope of their work:

  • "Development of β-globin gene correction in human hematopoietic stem cells as a potential durable treatment for sickle cell disease," 2021, Science Translational Medicine
  • "Genome editing of donor-derived T-cells to generate allogenic chimeric antigen receptor-modified T cells: Optimizing αβ T cell-depleted haploidentical hematopoietic stem cell transplantation," 2020, Haematologica
  • "Alloantigen-specific type 1 regulatory T cells suppress through CTLA-4 and PD-1 pathways and persist long-term in patients," 2021, Science Translational Medicine
  • "Type 1 regulatory T cell-mediated tolerance in health and disease," 2022, Frontiers in Immunology
  • "Gene therapy for Wiskott-Aldrich syndrome: History, new vectors, future directions," 2020, Journal of Allergy and Clinical Immunology

Maria Grazia Roncarolo has been recognized with the award of Member of Academia Europaea in 2005.

Best Publications

  • A CD4 + T-cell subset inhibits antigen-specific T-cell responses and prevents colitis

    Hervé Groux;Anne O'Garra;Mike Bigler;Matthieu Rouleau

  • Interleukin 10 (IL-10) and viral IL-10 strongly reduce antigen-specific human T cell proliferation by diminishing the antigen-presenting capacity of monocytes via downregulation of class II major histocompatibility complex expression.

    R de Waal Malefyt;J Haanen;H Spits;M G Roncarolo

  • Rapamycin selectively expands CD4+CD25+FoxP3+ regulatory T cells

    Manuela Battaglia;Angela Stabilini;Maria Grazia Roncarolo

  • Interleukin-10-secreting type 1 regulatory T cells in rodents and humans.

    Maria Grazia Roncarolo;Silvia Gregori;Manuela Battaglia;Rosa Bacchetta

  • Correction of ADA-SCID by Stem Cell Gene Therapy Combined with Nonmyeloablative Conditioning

    Alessandro Aiuti;Shimon Slavin;Memet Aker;Francesca Ficara

  • Lentiviral hematopoietic stem cell gene therapy benefits metachromatic leukodystrophy.

    Alessandra Biffi;Eugenio Montini;Laura Lorioli;Martina Cesani

  • Human Cd25+Cd4+ T Regulatory Cells Suppress Naive and Memory T Cell Proliferation and Can Be Expanded in Vitro without Loss of Function

    Megan K. Levings;Romina Sangregorio;Maria Grazia Roncarolo

  • Lentiviral Hematopoietic Stem Cell Gene Therapy in Patients with Wiskott-Aldrich Syndrome

    Alessandro Aiuti;Luca Biasco;Samantha Scaramuzza;Francesca Ferrua

  • Interleukin-10 induces a long-term antigen-specific anergic state in human CD4+ T cells.

    H Groux;M Bigler;J E de Vries;M G Roncarolo

  • Isolation and expression of human cytokine synthesis inhibitory factor cDNA clones: homology to Epstein-Barr virus open reading frame BCRFI.

    P Vieira;R de Waal-Malefyt;M N Dang;K E Johnson

  • Type 1 T regulatory cells.

    Maria Grazia Roncarolo;Rosa Bacchetta;Claudio Bordignon;Satwant Narula

  • Gene Therapy for Immunodeficiency Due to Adenosine Deaminase Deficiency

    Alessandro Aiuti;Federica Cattaneo;Stefania Galimberti;Ulrike Benninghoff

  • Activation-induced FOXP3 in human T effector cells does not suppress proliferation or cytokine production

    Sarah E. Allan;Sarah Q. Crome;Natasha K. Crellin;Laura Passerini

  • The X-linked lymphoproliferative-disease gene product SAP regulates signals induced through the co-receptor SLAM

    J. Sayos;C. Wu;M. Morra;N. Wang

  • Coexpression of CD49b and LAG-3 identifies human and mouse T regulatory type 1 cells

    Nicola Gagliani;Chiara F. Magnani;Samuel Huber;Monica E. Gianolini;Monica E. Gianolini

  • Rapamycin Promotes Expansion of Functional CD4+CD25+FOXP3+ Regulatory T Cells of Both Healthy Subjects and Type 1 Diabetic Patients

    Manuela Battaglia;Angela Stabilini;Barbara Migliavacca;Jutta Horejs-Hoeck

  • Reprogramming human T cell function and specificity with non-viral genome targeting

    Theodore L. Roth;Cristina Puig-Saus;Ruby Yu;Ruby Yu;Eric Shifrut;Eric Shifrut

  • IFN-α and IL-10 Induce the Differentiation of Human Type 1 T Regulatory Cells

    Megan K. Levings;Romina Sangregorio;Francesca Galbiati;Stefania Squadrone

  • Regulatory T cell immunotherapy for tolerance to self antigens and alloantigens in humans

    Maria Grazia Roncarolo;Manuela Battaglia

  • Regulatory T cells: recommendations to simplify the nomenclature

    Abul K Abbas;Christophe Benoist;Jeffrey A Bluestone;Daniel J Campbell

Frequent Co-Authors

Rosa Bacchetta
Rosa Bacchetta Stanford University
Alessandro Aiuti
Alessandro Aiuti Vita-Salute San Raffaele University
Silvia Gregori
Silvia Gregori Vita-Salute San Raffaele University
Luigi Naldini
Luigi Naldini Vita-Salute San Raffaele University
Claudio Bordignon
Claudio Bordignon MolMed (Italy)
Megan K. Levings
Megan K. Levings University of British Columbia
Fabio Ciceri
Fabio Ciceri Vita-Salute San Raffaele University
Anna Villa
Anna Villa National Academies of Sciences, Engineering, and Medicine
Nicola Gagliani
Nicola Gagliani Universität Hamburg
Marcus O. Muench
Marcus O. Muench University of California, San Francisco

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