The scientist’s investigation covers issues in Immunology, FOXP3, IL-2 receptor, Cell biology and Interleukin 10. Autoimmunity, Peripheral tolerance, Immune system, Immunopathology and IPEX syndrome are the core of her Immunology study. Her IPEX syndrome research is multidisciplinary, relying on both Autoimmune enteropathy and Immune dysregulation.
The study incorporates disciplines such as Jurkat cells, Transcription factor and Suppressor in addition to FOXP3. Her Cell biology study incorporates themes from In vitro, T cell, Cluster of differentiation, Transplant rejection and Perforin. In her research on the topic of Interleukin 10, Antigen presentation and Acquired immune system is strongly related with Antigen-presenting cell.
Her primary areas of investigation include Immunology, FOXP3, Immune system, T cell and Cell biology. Her research on Immunology frequently links to adjacent areas such as Cell therapy. Her FOXP3 research is multidisciplinary, incorporating elements of Cancer research, Immune tolerance, IPEX syndrome, Regulatory T cell and Effector.
Her Interleukin 10 study in the realm of Immune system connects with subjects such as Viral vector. Rosa Bacchetta works mostly in the field of T cell, limiting it down to topics relating to Antigen and, in certain cases, Stem cell. Her Cell biology research focuses on Cytokine and how it connects with LAG3 and CD49b.
The scientist’s investigation covers issues in FOXP3, Immune system, Immunology, IPEX syndrome and T cell. Her studies deal with areas such as Haematopoiesis, Cancer research, Antigen, CTLA-4 and Effector as well as FOXP3. Rosa Bacchetta interconnects Cell culture and Cell biology in the investigation of issues within Immune system.
Her research in Cell biology focuses on subjects like Immune tolerance, which are connected to Bioinformatics and Clinical trial. Her research in Immune dysregulation, Regulatory T cell, Flow cytometry, Autoimmunity and Peripheral tolerance are components of Immunology. Her T cell research focuses on Reprogramming and how it relates to Cancer immunotherapy and Computational biology.
Her primary areas of investigation include FOXP3, Immune system, Immunology, Computational biology and Antigen. Her biological study spans a wide range of topics, including Autoimmune enteropathy, Primary immunodeficiency, CD8 and Cell biology. Her research investigates the connection between Cell biology and topics such as Cytometry that intersect with issues in Immune tolerance.
Her study in T cell and Acquired immune system falls within the category of Immune system. Her study deals with a combination of Immunology and Cell counting. Her Antigen research includes themes of Cell, Function and Effector.
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Interleukin-10-secreting type 1 regulatory T cells in rodents and humans.
Maria Grazia Roncarolo;Silvia Gregori;Manuela Battaglia;Rosa Bacchetta.
Immunological Reviews (2006)
Type 1 T regulatory cells.
Maria Grazia Roncarolo;Rosa Bacchetta;Claudio Bordignon;Satwant Narula.
Immunological Reviews (2001)
Activation-induced FOXP3 in human T effector cells does not suppress proliferation or cytokine production
Sarah E. Allan;Sarah Q. Crome;Natasha K. Crellin;Laura Passerini.
International Immunology (2007)
Chemically modified guide RNAs enhance CRISPR-Cas genome editing in human primary cells
Ayal Hendel;Rasmus O Bak;Joseph T Clark;Andrew B Kennedy.
Nature Biotechnology (2015)
Coexpression of CD49b and LAG-3 identifies human and mouse T regulatory type 1 cells
Nicola Gagliani;Chiara F. Magnani;Samuel Huber;Monica E. Gianolini;Monica E. Gianolini.
Nature Medicine (2013)
Defective regulatory and effector T cell functions in patients with FOXP3 mutations
Rosa Bacchetta;Laura Passerini;Eleonora Gambineri;Minyue Dai.
Journal of Clinical Investigation (2006)
The role of 2 FOXP3 isoforms in the generation of human CD4+ Tregs
Sarah E. Allan;Laura Passerini;Rosa Bacchetta;Natasha Crellin.
Journal of Clinical Investigation (2005)
The Role of IL-10 and TGF-β in the Differentiation and Effector Function of T Regulatory Cells
Megan K. Levings;Rosa Bacchetta;Ute Schulz;Maria Grazia Roncarolo.
International Archives of Allergy and Immunology (2002)
Reprogramming human T cell function and specificity with non-viral genome targeting
Theodore L. Roth;Cristina Puig-Saus;Ruby Yu;Ruby Yu;Eric Shifrut;Eric Shifrut.
High levels of interleukin 10 production in vivo are associated with tolerance in SCID patients transplanted with HLA mismatched hematopoietic stem cells.
R Bacchetta;M Bigler;J L Touraine;R Parkman.
Journal of Experimental Medicine (1994)
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