World's Best Scientists 2026 revealed!

D-Index & Metrics

Immunology

D-Index
44
Citations
17168
World Ranking
4737
National Ranking
227

Overview

Hervé Groux is affiliated with Grenoble Alpes University in France. Their research primarily focuses on the fields of Medicine and Veterinary sciences, with particular emphasis on Dermatology and Small Animals as subfields. Other areas of study include Immunology and Allergy, Economics and Econometrics, and Computational Theory and Mathematics.

The scientist's work covers several main topics, including:

  • Contact Dermatitis and Allergies
  • Animal testing and alternatives
  • Skin Protection and Aging
  • Allergic Rhinitis and Sensitization
  • Dermatology and Skin Diseases
  • Health Systems, Economic Evaluations, Quality of Life
  • Computational Drug Discovery Methods

Hervé Groux has published in a variety of scientific venues. Frequent publication outlets include:

  • Toxicology in Vitro
  • Cosmetics
  • Toxicology Letters
  • Revue des Maladies Respiratoires
  • Polymers

Frequent coauthors in their publications include:

  • Françoise Cottrez
  • Mickaël Puginier
  • Alicia Roso
  • Elodie Boitel
  • C. Gerbeix

Selected recent papers by Hervé Groux include:

  • In vitro testing strategy for assessing the skin sensitizing potential of "difficult to test" cosmetic ingredients, 2020, Toxicology in Vitro
  • Pre-validation of SENS-IS assay for in vitro skin sensitization of medical devices, 2020, Toxicology in Vitro
  • Strategy to Avoid Skin Sensitization: Application to Botanical Cosmetic Ingredients, 2022, Cosmetics
  • The EyeIRR-IS assay: Development and evaluation of an in vitro assay to measure the eye irritation sub-categorization of liquid chemicals, 2020, Toxicology in Vitro
  • Validation of a new 3D epidermis model for the SENS-IS assay to evaluate skin sensitization potency of chemicals, 2025, Toxicology in Vitro

Best Publications

  • A CD4 + T-cell subset inhibits antigen-specific T-cell responses and prevents colitis

    Hervé Groux;Anne O'Garra;Mike Bigler;Matthieu Rouleau

  • Characterization of Dendritic Cells that Induce Tolerance and T Regulatory 1 Cell Differentiation In Vivo

    Abdelilah Wakkach;Nathalie Fournier;Valérie Brun;Jean-Philippe Breittmayer

  • Interleukin-10 induces a long-term antigen-specific anergic state in human CD4+ T cells.

    H Groux;M Bigler;J E de Vries;M G Roncarolo

  • Activation-induced death by apoptosis in CD4+ T cells from human immunodeficiency virus-infected asymptomatic individuals.

    H Groux;G Torpier;D Monté;Y Mouton

  • Inhibitory and Stimulatory Effects of IL-10 on Human CD8+ T Cells

    H Groux;M Bigler;J E de Vries;M G Roncarolo

  • T Regulatory Cells 1 Inhibit a Th2-Specific Response In Vivo

    Françoise Cottrez;Steven D. Hurst;Robert L. Coffman;Hervé Groux

  • Transplantation of a multipotent cell population from human adipose tissue induces dystrophin expression in the immunocompetent mdx mouse

    Anne-Marie Rodriguez;Didier F. Pisani;Claude A. Dechesne;Claude Turc-Carel

  • SENS-IS, a 3D reconstituted epidermis based model for quantifying chemical sensitization potency: Reproducibility and predictivity results from an inter-laboratory study.

    Françoise Cottrez;Elodie Boitel;Jean-Claude Ourlin;Jean-Luc Peiffer

  • CD44 contributes to T cell activation.

    S Huet;H Groux;B Caillou;H Valentin

  • Regulatory T cells and inflammatory bowel disease

    Hervé Groux;Fiona Powrie

  • Induction of a Regulatory T Cell Type 1 Response Reduces the Development of Atherosclerosis in Apolipoprotein E–Knockout Mice

    Ziad Mallat;Andrea Gojova;Valérie Brun;Bruno Esposito

  • A Transgenic Model to Analyze the Immunoregulatory Role of IL-10 Secreted by Antigen-Presenting Cells

    Hervé Groux;Françoise Cottrez;Matthieu Rouleau;Smita Mauze

  • Regulation of TGF-β Response During T Cell Activation Is Modulated by IL-10

    Françoise Cottrez;Hervé Groux

  • Anti-inflammatory properties of the μ opioid receptor support its use in the treatment of colon inflammation

    David Philippe;Laurent Dubuquoy;Hervé Groux;Valérie Brun

  • A comparative study between T regulatory type 1 and CD4+CD25+ T cells in the control of inflammation.

    Arnaud Foussat;Françoise Cottrez;Valérie Brun;Nathalie Fournier

  • Transgenic interleukin 10 prevents induction of experimental autoimmune encephalomyelitis.

    Daniel J. Cua;Herve Groux;David R. Hinton;Stephen A. Stohlman

  • Rho-Associated Protein Kinase Contributes to Early Atherosclerotic Lesion Formation in Mice

    Ziad Mallat;Andrea Gojova;Vincent Sauzeau;Valérie Brun

  • The complex role of interleukin-10 in autoimmunity.

    Hervé Groux;Françoise Cottrez

  • Type 1 T-regulatory cells: their role in the control of immune responses.

    Herve Groux

  • Leukocyte-Derived Interleukin 10 Is Required for Protection Against Atherosclerosis in Low-Density Lipoprotein Receptor Knockout Mice

    Stéphane Potteaux;Bruno Esposito;Olivia van Oostrom;Valérie Brun

Frequent Co-Authors

Maria Grazia Roncarolo
Maria Grazia Roncarolo Stanford University
André Capron
André Capron Institut Pasteur
Rosa Bacchetta
Rosa Bacchetta Stanford University
Ziad Mallat
Ziad Mallat University of Cambridge
Alain Bernard
Alain Bernard Grenoble Alpes University
Christophe Baudouin
Christophe Baudouin Institut de la Vision
Gérard Torpier
Gérard Torpier Institut Pasteur
Pascal Barbry
Pascal Barbry Centre national de la recherche scientifique, CNRS
Dominique Stehelin
Dominique Stehelin Institut Pasteur

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