Gerardo Morfini

Overview

Best Publications

• Wild-type and mutant SOD1 share an aberrant conformation and a common pathogenic pathway in ALS

  Daryl A. Bosco;Gerardo A. Morfini;Gerardo A. Morfini;N. Murat Karabacak;Yuyu Song;Yuyu Song

  767
  Citations

• Axonal Transport Defects in Neurodegenerative Diseases

  Gerardo A. Morfini;Matthew Burns;Lester I. Binder;Nicholas M. Kanaan

  544
  Citations

• Glycogen synthase kinase 3 phosphorylates kinesin light chains and negatively regulates kinesin-based motility

  Gerardo Morfini;Gerardo Morfini;Györgyi Szebenyi;Ravindhra Elluru;Ravindhra Elluru;Nancy Ratner;Nancy Ratner

  516
  Citations

• Neuropathogenic Forms of Huntingtin and Androgen Receptor Inhibit Fast Axonal Transport

  Györgyi Szebenyi;Gerardo A. Morfini;Gerardo A. Morfini;Alyssa Babcock;Milena Gould

  386
  Citations

• Reelin-mediated signaling locally regulates protein kinase B/Akt and glycogen synthase kinase 3β

  Uwe Beffert;Gerardo Morfini;Hans H. Bock;Huichuan Reyna

  362
  Citations

• Alterations in axonal transport motor proteins in sporadic and experimental Parkinson's disease.

  Yaping Chu;Gerardo A. Morfini;Lori B. Langhamer;Yinzhen He

  355
  Citations

• Alzheimer's Presenilin 1 Mutations Impair Kinesin-Based Axonal Transport

  Gustavo Pigino;Gerardo Morfini;Alejandra Pelsman;Mark P. Mattson

  354
  Citations

• A novel CDK5-dependent pathway for regulating GSK3 activity and kinesin-driven motility in neurons

  Gerardo Morfini;Gerardo Morfini;Györgyi Szebenyi;Hannah Brown;Harish C Pant

  322
  Citations

• Pathogenic Forms of Tau Inhibit Kinesin-Dependent Axonal Transport through a Mechanism Involving Activation of Axonal Phosphotransferases

  Nicholas M. Kanaan;Gerardo A. Morfini;Gerardo A. Morfini;Nichole E. LaPointe;Gustavo F. Pigino;Gustavo F. Pigino

  316
  Citations

• The amino terminus of tau inhibits kinesin-dependent axonal transport: Implications for filament toxicity

  Nichole E. LaPointe;Gerardo A. Morfini;Gerardo A. Morfini;Gustavo F. Pigino;Gustavo F. Pigino;Irina N. Gaisina

  290
  Citations

• Pathogenic huntingtin inhibits fast axonal transport by activating JNK3 and phosphorylating kinesin.

  Gerardo A Morfini;Yi-Mei You;Sarah L Pollema;Sarah L Pollema;Agnieszka Kaminska

  290
  Citations

• Axonal Transport, Amyloid Precursor Protein, Kinesin-1, and the Processing Apparatus: Revisited

  Orly Lazarov;Gerardo A. Morfini;Edward B. Lee;Mohamed H. Farah

  268
  Citations

• Disruption of fast axonal transport is a pathogenic mechanism for intraneuronal amyloid beta

  G. Pigino;G. Morfini;Y. Atagi;A. Deshpande

  264
  Citations

• Effects of eribulin, vincristine, paclitaxel and ixabepilone on fast axonal transport and kinesin-1 driven microtubule gliding: implications for chemotherapy-induced peripheral neuropathy.

  Nichole E. LaPointe;Gerardo A. Morfini;Scott T. Brady;Stuart C. Feinstein

  261
  Citations

• Evidence for the Participation of the Neuron-Specific CDK5 Activator P35 during Laminin-Enhanced Axonal Growth

  Gabriela Paglini;Gustavo Pigino;Patricia Kunda;Gerardo Morfini

  247
  Citations

• Axonal degeneration in Alzheimer's disease: When signaling abnormalities meet the axonal transport system

  Nicholas M. Kanaan;Gustavo F. Pigino;Scott T. Brady;Orly Lazarov

  224
  Citations

• JNK mediates pathogenic effects of polyglutamine-expanded androgen receptor on fast axonal transport

  Gerardo Morfini;Gustavo Pigino;Györgyi Szebenyi;Yimei You

  224
  Citations

• Differential vulnerability of neurons in Huntington’s disease: the role of cell type‐specific features

  Ina Han;YiMei You;Jeffrey H. Kordower;Scott T. Brady

  186
  Citations

• Impairments in fast axonal transport and motor neuron deficits in transgenic mice expressing familial Alzheimer's disease-linked mutant presenilin 1.

  Orly Lazarov;Gerardo A. Morfini;Gustavo Pigino;Archana Gadadhar

  157
  Citations

• 1-Methyl-4-phenylpyridinium affects fast axonal transport by activation of caspase and protein kinase C

  G. Morfini;G. Pigino;K. Opalach;Y. Serulle

  156
  Citations