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Biology and Biochemistry

D-Index
81
Citations
22725
World Ranking
3915
National Ranking
1935

Research.com Recognitions

  • 2013 - Fellow of the American Association for the Advancement of Science (AAAS)

Overview

Scott T. Brady is affiliated with the University of Illinois at Chicago in the United States. Their research mainly spans the fields of Biochemistry, Genetics and Molecular Biology, with additional contributions to Medicine. Within these disciplines, their focus includes molecular biology, physiology, cell biology, neurology, and genetics.

Their scientific inquiries concentrate on several key topics:

  • Alzheimer's disease research and treatments
  • Microtubule and mitosis dynamics
  • Neuroinflammation and neurodegeneration mechanisms
  • RNA research and splicing
  • Cellular transport and secretion
  • Neuroscience and neuropharmacology research
  • Cholinesterase and neurodegenerative diseases

Recent papers authored or coauthored by Scott T. Brady include:

  • "Tau: A Signaling Hub Protein" (2021) published in Frontiers in Molecular Neuroscience
  • "Relevance of transgenic mouse models for Alzheimer's disease" (2020) in Progress in Molecular Biology and Translational Science
  • "Defined Tau Phosphospecies Differentially Inhibit Fast Axonal Transport Through Activation of Two Independent Signaling Pathways" (2021) in Frontiers in Molecular Neuroscience
  • "Tau phosphorylation and PAD exposure in regulation of axonal growth" (2023) in Frontiers in Cell and Developmental Biology
  • "Engagement of Neurotropic Viruses in Fast Axonal Transport: Mechanisms, Potential Role of Host Kinases and Implications for Neuronal Dysfunction" (2021) in Frontiers in Cellular Neuroscience

Their work commonly appears in the following publication venues:

  • Frontiers in Molecular Neuroscience (3 publications)
  • bioRxiv (Cold Spring Harbor Laboratory) (2 publications)
  • Progress in Molecular Biology and Translational Science (1 publication)
  • Frontiers in Cell and Developmental Biology (1 publication)
  • Frontiers in Cellular Neuroscience (1 publication)

Scott T. Brady has collaborated frequently with several researchers, including:

  • Gerardo Morfini (6 publications)
  • Sarah Morris (4 publications)
  • Yuyu Song (3 publications)
  • Leon M. Tai (2 publications)
  • Karin Bechberger (2 publications)

In addition to journal articles, Scott T. Brady has contributed to scholarly books, such as the publication by RAND Corporation eBooks titled "Managing Adverse and Reportable Information Regarding U.S. Military Officers: 2019 Update" released in 2022.

Recognition for their scientific contributions includes being named a Fellow of the American Association for the Advancement of Science (AAAS) in 2013.

Best Publications

  • Local modulation of neurofilament phosphorylation, axonal caliber, and slow axonal transport by myelinating Schwann cells.

    Sylvie M. de Waegh;Virginia M.-Y. Lee;Scott T. Brady

  • A novel brain ATPase with properties expected for the fast axonal transport motor

    Scott T. Brady

  • Wild-type and mutant SOD1 share an aberrant conformation and a common pathogenic pathway in ALS

    Daryl A. Bosco;Gerardo A. Morfini;Gerardo A. Morfini;N. Murat Karabacak;Yuyu Song;Yuyu Song

  • Submolecular domains of bovine brain kinesin identified by electron microscopy and monoclonal antibody decoration

    Nobutaka Hirokawa;K.Kevin Pfister;Hiroshi Yorifuji;Mark C. Wagner

  • Axonal Transport Defects in Neurodegenerative Diseases

    Gerardo A. Morfini;Matthew Burns;Lester I. Binder;Nicholas M. Kanaan

  • Glycogen synthase kinase 3 phosphorylates kinesin light chains and negatively regulates kinesin-based motility

    Gerardo Morfini;Gerardo Morfini;Györgyi Szebenyi;Ravindhra Elluru;Ravindhra Elluru;Nancy Ratner;Nancy Ratner

  • Fast axonal transport in squid giant axon

    Robert Day Allen;Janis Metuzals;Ichiji Tasaki;Scott T. Brady

  • Fast axonal transport in extruded axoplasm from squid giant axon

    Scott T. Brady;Raymond J. Lasek;Robert D. Allen

  • Direct interaction of microtubule- and actin-based transport motors.

    Jian Dong Huang;Scott T. Brady;Bruce W. Richards;David Stenoien

  • Axonal transport of the cytoplasmic matrix.

    R J Lasek;J A Garner;S T Brady

  • Post-translational modifications of tubulin: pathways to functional diversity of microtubules

    Yuyu Song;Scott T. Brady

  • Neuropathogenic Forms of Huntingtin and Androgen Receptor Inhibit Fast Axonal Transport

    Györgyi Szebenyi;Gerardo A. Morfini;Gerardo A. Morfini;Alyssa Babcock;Milena Gould

  • Native structure and physical properties of bovine brain kinesin and identification of the ATP-binding subunit polypeptide.

    George S. Bloom;Mark C. Wagner;K. Kevin Pfister;Scott T. Brady

  • Reelin-mediated signaling locally regulates protein kinase B/Akt and glycogen synthase kinase 3β

    Uwe Beffert;Gerardo Morfini;Hans H. Bock;Huichuan Reyna

  • Alterations in axonal transport motor proteins in sporadic and experimental Parkinson's disease.

    Yaping Chu;Gerardo A. Morfini;Lori B. Langhamer;Yinzhen He

  • Alzheimer's Presenilin 1 Mutations Impair Kinesin-Based Axonal Transport

    Gustavo Pigino;Gerardo Morfini;Alejandra Pelsman;Mark P. Mattson

  • Monoclonal antibodies to kinesin heavy and light chains stain vesicle-like structures, but not microtubules, in cultured cells.

    K. K. Pfister;M. C. Wagner;D. L. Stenoien;Scott T. Brady

  • Kinesin associates with anterogradely transported membranous organelles in vivo

    Nobutaka Hirokawa;Reiko Sato-Yoshitake;Naoto Kobayashi;K. Kevin Pfister

  • A monoclonal antibody against kinesin inhibits both anterograde and retrograde fast axonal transport in squid axoplasm.

    Scott T. Brady;K. Kevin Pfister;George S. Bloom

  • A novel CDK5-dependent pathway for regulating GSK3 activity and kinesin-driven motility in neurons

    Gerardo Morfini;Gerardo Morfini;Györgyi Szebenyi;Hannah Brown;Harish C Pant

Frequent Co-Authors

Gerardo Morfini
Gerardo Morfini University of Illinois at Chicago
George S. Bloom
George S. Bloom University of Virginia
Nicholas M. Kanaan
Nicholas M. Kanaan Michigan State University
Philip L. Leopold
Philip L. Leopold Cornell University
Mutsuyuki Sugimori
Mutsuyuki Sugimori New York University
Rodolfo R. Llinás
Rodolfo R. Llinás New York University
Jeffrey H. Kordower
Jeffrey H. Kordower Arizona State University
Nancy Ratner
Nancy Ratner Cincinnati Children's Hospital Medical Center
Sangram S. Sisodia
Sangram S. Sisodia University of Chicago
Virginia M.-Y. Lee
Virginia M.-Y. Lee University of Pennsylvania

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