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Philip L. Leopold

Philip L. Leopold

D-Index & Metrics

Biology and Biochemistry

D-Index
47
Citations
8265
World Ranking
18697
National Ranking
7643

Overview

Philip L. Leopold is affiliated with Cornell University in the United States and has contributed extensively to the field of medicine, with a particular focus on pulmonary and respiratory medicine. Their research encompasses a range of subfields such as infectious diseases, genetics, management, monitoring, policy and law, and physiology.

The scientist's work spans several important medical topics including interstitial lung diseases and idiopathic pulmonary fibrosis, neonatal respiratory health research, landslides and related hazards, virus-based gene therapy research, COVID-19 clinical research studies, long-term effects of COVID-19, and CRISPR and genetic engineering.

Philip L. Leopold has authored multiple papers in reputable journals. Notable recent publications include:

  • Expression of the SARS-CoV-2 ACE2 Receptor in the Human Airway Epithelium, 2020, American Journal of Respiratory and Critical Care Medicine
  • Dysregulation of club cell biology in idiopathic pulmonary fibrosis, 2020, PLoS ONE
  • Cell-specific expression of lung disease risk-related genes in the human small airway epithelium, 2020, Respiratory Research
  • Smoking shifts human small airway epithelium club cells toward a lesser differentiated population, 2021, npj Genomic Medicine
  • Single-Cell Transcriptome Analysis of Mouse Liver Cell-Specific Tropism and Transcriptional Dysregulation Following Intravenous Administration of AAVrh.10 Vectors, 2020, Human Gene Therapy

Frequent co-authors include Ronald G. Crystal, Mahboubeh Rostami, Jason G. Mezey, Yael Strulovici-Barel, and Sarah L. O'Beirne, indicating collaborative work in overlapping research interests.

The scientist has published frequently in journals and venues such as:

  • Zenodo (CERN European Organization for Nuclear Research)
  • American Journal of Respiratory and Critical Care Medicine
  • Respiratory Research
  • PLoS ONE
  • npj Genomic Medicine

This profile indicates a research trajectory centered on respiratory health, disease pathogenesis, and genetic factors influencing pulmonary conditions, integrating experimental and clinical approaches across various medical subfields.

Best Publications

  • A SNAIL1-SMAD3/4 transcriptional repressor complex promotes TGF-beta mediated epithelial-mesenchymal transition.

    Theresa Vincent;Theresa Vincent;Etienne P. A. Neve;Etienne P. A. Neve;Jill R. Johnson;Alexander Kukalev

  • Induction of the hair growth phase in postnatal mice by localized transient expression of Sonic hedgehog

    Noboru Sato;Philip L. Leopold;Ronald G. Crystal

  • Fluorescent virions: dynamic tracking of the pathway of adenoviral gene transfer vectors in living cells

    Philip L. Leopold;Barbara Ferris;Irene Grinberg;Stefan Worgall

  • Dynein- and microtubule-mediated translocation of adenovirus serotype 5 occurs after endosomal lysis.

    Philip L. Leopold;Geri Kreitzer;Naoki Miyazawa;Stephanie Rempel

  • Airway epithelial CFTR mRNA expression in cystic fibrosis patients after repetitive administration of a recombinant adenovirus

    B G Harvey;P L Leopold;N R Hackett;T M Grasso

  • Modification of gene expression of the small airway epithelium in response to cigarette smoking

    Ben Gary Harvey;Adriana Heguy;Philip L. Leopold;Brendan J. Carolan

  • CAR-dependent and CAR-independent pathways of adenovirus vector–mediated gene transfer and expression in human fibroblasts

    Chisa Hidaka;Eric Milano;Philip L. Leopold;Jeffrey M. Bergelson

  • Smoking is associated with shortened airway cilia.

    Philip L. Leopold;Michael J. O'Mahony;X. Julie Lian;Ann E. Tilley

  • Sphingomyelinase Treatment Induces ATP-independent Endocytosis

    Xiaohui Zha;Lynda M. Pierini;Philip L. Leopold;Paul J. Skiba

  • Fiber swap between adenovirus subgroups B and C alters intracellular trafficking of adenovirus gene transfer vectors.

    Naoki Miyazawa;Philip L. Leopold;Neil R. Hackett;Barbara Ferris

  • Expression of the SARS-CoV-2 ACE2 Receptor in the Human Airway Epithelium.

    Haijun Zhang;Mahboubeh R. Rostami;Philip L. Leopold;Jason G. Mezey

  • Cytoplasmic Dynein Mediates Adenovirus Binding to Microtubules

    Samir A. Kelkar;K. Kevin Pfister;Ronald G. Crystal;Philip L. Leopold

  • Oligomerized transferrin receptors are selectively retained by a lumenal sorting signal in a long-lived endocytic recycling compartment.

    Eric W. Marsh;Philip L. Leopold;Nancy L. Jones;Frederick R. Maxfield

  • Adenovirus Serotype 7 Retention in a Late Endosomal Compartment prior to Cytosol Escape Is Modulated by Fiber Protein

    Naoki Miyazawa;Ronald G. Crystal;Philip L. Leopold

  • High Levels of Persistent Expression of α1-Antitrypsin Mediated by the Nonhuman Primate Serotype rh.10 Adeno-associated Virus Despite Preexisting Immunity to Common Human Adeno-associated Viruses

    Bishnu P. De;Adriana Heguy;Neil R. Hackett;Barbara Ferris

  • Association of kinesin with characterized membrane-bounded organelles.

    Philip L. Leopold;Alasdair W. McDowall;K. Kevin Pfister;George S. Bloom

  • Role of Alveolar Macrophages in Rapid Elimination of Adenovirus Vectors Administered to the Epithelial Surface of the Respiratory Tract

    S Worgall;P L Leopold;G Wolff;B Ferris

  • Intracellular trafficking of adenovirus: many means to many ends

    Philip L. Leopold;Ronald G. Crystal

  • Up-regulation of Expression of the Ubiquitin Carboxyl-Terminal Hydrolase L1 Gene in Human Airway Epithelium of Cigarette Smokers

    Brendan J. Carolan;Adriana Heguy;Ben-Gary Harvey;Philip L. Leopold

  • Viral strategies for intracellular trafficking: motors and microtubules.

    Philip L. Leopold;K. Kevin Pfister

Frequent Co-Authors

Ronald G. Crystal
Ronald G. Crystal Cornell University
Neil R. Hackett
Neil R. Hackett Cornell University
Scott T. Brady
Scott T. Brady University of Illinois at Chicago
James M. Wilson
James M. Wilson University of Pennsylvania
George S. Bloom
George S. Bloom University of Virginia
Frederick R. Maxfield
Frederick R. Maxfield Cornell University
Guangping Gao
Guangping Gao University of Massachusetts Chan Medical School
Mutsuyuki Sugimori
Mutsuyuki Sugimori New York University
Angela M. Christiano
Angela M. Christiano Columbia University

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