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Imre Kovesdi

Imre Kovesdi

D-Index & Metrics

Molecular Biology

D-Index
73
Citations
17977
World Ranking
1285
National Ranking
661

Overview

Imre Kovesdi is affiliated with GenVec in the United States and has a research focus primarily in the fields of Medicine and Biochemistry, Genetics and Molecular Biology. Their work spans several subfields including Infectious Diseases, Epidemiology, Molecular Biology, Immunology, and Genetics.

Their research topics cover a range of areas such as SARS-CoV-2 and COVID-19 Research, Virology and Viral Diseases, Virus-based gene therapy research, Immune responses and vaccinations, Angiogenesis and VEGF in Cancer, Cancer, Hypoxia, and Metabolism, and vaccines and immunoinformatics approaches.

Kovesdi's recent publications include:

  • Editorial: Fighting fire with fire: Using non-pathogenic viruses to control unrelated infections, 2022, Frontiers in Immunology
  • Sequential Combination of a Strong Interferon Inducer Viral Vector With Low Doses of Nivolumab Plus Ipilimumab Could Provide Functional Cure in Chronic Hepatitis B Virus infections: Technical Report Proposing a New Modality, 2022, Cureus
  • An Orally Administered Nonpathogenic Attenuated Vaccine Virus Can Be Used to Control SARS-CoV-2 Infection: A Complementary Plan B to COVID-19 Vaccination, 2022, Cureus
  • Combination Therapy for the Treatment of Shingles with an Immunostimulatory Vaccine Virus and Acyclovir, 2023, Pharmaceuticals
  • A Clinically Validated, Broadly Active, Oral Viral SuperinfectionTherapy Could Mitigate Symptoms in Early-stage COVID-19 Patients, 2022, Infectious Disorders - Drug Targets

Kovesdi has collaborated frequently with a number of coauthors, including:

  • Tibor Bakács
  • Volker Sandig
  • Rifaat Safadi
  • Marc Van Ranst
  • Peter M. Chumakov

The most frequent publication venues where Kovesdi's work appears include Preprints.org, Cureus, Frontiers in Immunology, Pharmaceuticals, and Infectious Disorders - Drug Targets.

Best Publications

  • The Coxsackievirus-Adenovirus Receptor Protein Can Function as a Cellular Attachment Protein for Adenovirus Serotypes from Subgroups A, C, D, E, and F

    Peter W. Roelvink;Alena Lizonova;Jennifer G. M. Lee;Yuan Li

  • Increased in vitro and in vivo gene transfer by adenovirus vectors containing chimeric fiber proteins.

    Thomas J. Wickham;Edith Tzeng;Larry L. Shears;Peter W. Roelvink

  • Identification of a cellular transcription factor involved in E1A trans-activation

    Imre Kovesdi;Ronald Reichel;Joseph R. Nevins

  • Identification of a Conserved Receptor-Binding Site on the Fiber Proteins of CAR-Recognizing Adenoviridae

    Peter W. Roelvink;Gai Mi Lee;David A. Einfeld;Imre Kovesdi

  • Reversal of impaired wound repair in iNOS-deficient mice by topical adenoviral-mediated iNOS gene transfer.

    K. Yamasaki;H. D. J. Edington;C. Mcclosky;E. Tzeng

  • Adenovirus targeted to heparan-containing receptors increases its gene delivery efficiency to multiple cell types

    Thomas J. Wickham;Peter W. Roelvink;Douglas E. Brough;Imre Kovesdi

  • Biologic bypass with the use of adenovirus-mediated gene transfer of the complementary deoxyribonucleic acid for vascular endothelial growth factor 121 improves myocardial perfusion and function in the ischemic porcine heart

    Charles A. Mack;Shailen R. Patel;Eric A. Schwarz;Pat Zanzonico

  • Targeted adenovirus gene transfer to endothelial and smooth muscle cells by using bispecific antibodies.

    T. J. Wickham;D. M. Segal;P. W. Roelvink;M. E. Carrion

  • Role of an adenovirus E2 promoter binding factor in E1A-mediated coordinate gene control

    Imre Kovesdi;Ronald Reichel;Joseph R. Nevins

  • Selectivity of a replication-competent adenovirus for human breast carcinoma cells expressing the MUC1 antigen

    Toshikazu Kurihara;Douglas E. Brough;Imre Kovesdi;Donald W. Kufe

  • Adenovirus infection stimulates the Raf/MAPK signaling pathway and induces interleukin-8 expression.

    J T Bruder;I Kovesdi

  • “Sero-Switch” Adenovirus-Mediated In Vivo Gene Transfer: Circumvention of Anti-Adenovirus Humoral Immune Defenses Against Repeat Adenovirus Vector Administration by Changing the Adenovirus Serotype

    Andrea Mastrangeli;Ben-Gary Harvey;Jeffrey Yao;Gerhard Wolff

  • Targeting of adenovirus penton base to new receptors through replacement of its RGD motif with other receptor-specific peptide motifs.

    T J Wickham;M E Carrion;I Kovesdi

  • Adenoviral vectors for gene transfer

    Imre Kovesdi;Douglas E Brough;Joseph T Bruder;Thomas J Wickham

  • Reducing the Native Tropism of Adenovirus Vectors Requires Removal of both CAR and Integrin Interactions

    David A. Einfeld;Rosanna Schroeder;Peter W. Roelvink;Alena Lizonova

  • Efficient inhibition of intimal hyperplasia by adenovirus-mediated inducible nitric oxide synthase gene transfer to rats and pigs in vivo

    Larry L. Shears;Melina R. Kibbe;Alan D. Murdock;Timothy R. Billiar

  • Inducible nitric oxide synthase suppresses the development of allograft arteriosclerosis.

    Larry L. Shears;Nobuyoshi Kawaharada;Edith Tzeng;Timothy R. Billiar

  • Circumvention of Anti-Adenovirus Neutralizing Immunity by Administration of an Adenoviral Vector of an Alternate Serotype

    Charles A. Mack;Wen-Ru Song;Heather Carpenter;Tom J. Wickham

  • Airway epithelial CFTR mRNA expression in cystic fibrosis patients after repetitive administration of a recombinant adenovirus

    B G Harvey;P L Leopold;N R Hackett;T M Grasso

  • A gene transfer vector-cell line system for complete functional complementation of adenovirus early regions E1 and E4.

    D E Brough;A Lizonova;C Hsu;V A Kulesa

Frequent Co-Authors

Timothy R. Billiar
Timothy R. Billiar University of Pittsburgh
Ronald G. Crystal
Ronald G. Crystal Cornell University
Neil R. Hackett
Neil R. Hackett Cornell University
Maurizio C. Capogrossi
Maurizio C. Capogrossi Johns Hopkins University
Johnny Huard
Johnny Huard The University of Texas Health Science Center at Houston
Simon C. Watkins
Simon C. Watkins University of Pittsburgh
Timothy O'Brien
Timothy O'Brien University of Minnesota
Paul D. Robbins
Paul D. Robbins University of Minnesota
Toren Finkel
Toren Finkel University of Pittsburgh
David T. Curiel
David T. Curiel Washington University in St. Louis

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