World's Best Scientists 2026 revealed!

D-Index & Metrics

Biology and Biochemistry

D-Index
122
Citations
109002
World Ranking
567
National Ranking
359

Research.com Recognitions

  • 2013 - Fellow of the American Association for the Advancement of Science (AAAS)

Overview

Toren Finkel is affiliated with the University of Pittsburgh in the United States. Their research spans the intersecting areas of biochemistry, genetics, molecular biology, and medicine, with a significant focus on molecular biology and physiology among other subfields. The scientist's work addresses topics related to autophagy in disease and therapy, telomeres, telomerase, and senescence, mitochondrial function and pathology, as well as single-cell and spatial transcriptomics.

Finkel has authored or co-authored multiple recent papers including:

  • Guidelines for measuring reactive oxygen species and oxidative damage in cells and in vivo, 2022, Nature Metabolism
  • A phosphoinositide signalling pathway mediates rapid lysosomal repair, 2022, Nature
  • Mitochondria as intracellular signaling platforms in health and disease, 2020, The Journal of Cell Biology
  • NIH SenNet Consortium to map senescent cells throughout the human lifespan to understand physiological health, 2022, Nature Aging
  • Lysosomes in senescence and aging, 2023, EMBO Reports

Frequent coauthors collaborating with Finkel include Bill B. Chen, Travis Lear, Mads Larsen, Jason R. Kennerdell, and Bo Lin. These partnerships indicate a consistent collaborative research environment within their scientific inquiries.

Finkel's publications are commonly found in venues such as bioRxiv (Cold Spring Harbor Laboratory), Cancer Research, JCI Insight, Nature Communications, and Proceedings of the National Academy of Sciences. These venues reflect the interdisciplinary and translational nature of their research.

Within their main fields of study, the scientist's 113 publications in biochemistry, genetics, and molecular biology, alongside 92 in medicine, demonstrate a dual focus bridging fundamental biological mechanisms and clinical implications. Their subfields include molecular biology with 73 publications, physiology with 28, immunology with 16, epidemiology with 15, and pulmonary and respiratory medicine with 9.

The primary topics of Finkel's research include:

  • Autophagy in Disease and Therapy
  • Telomeres, Telomerase, and Senescence
  • Mitochondrial Function and Pathology
  • Single-cell and spatial transcriptomics
  • Genetics, Aging, and Longevity in Model Organisms
  • Interferon and Immune Responses
  • Bacillus and Francisella Bacterial Research

Among the honors received, Finkel was named a Fellow of the American Association for the Advancement of Science (AAAS) in 2013.

Best Publications

  • Oxidants, oxidative stress and the biology of ageing.

    Toren Finkel;Nikki J. Holbrook

  • Guidelines for the use and interpretation of assays for monitoring autophagy

    Daniel J. Klionsky;Fabio C. Abdalla;Hagai Abeliovich;Robert T. Abraham

  • Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

    Daniel J. Klionsky;Kotb Abdelmohsen;Akihisa Abe;Joynal Abedin

  • Mitochondria, Oxidants, and Aging

    Robert S. Balaban;Shino Nemoto;Toren Finkel

  • Circulating Endothelial Progenitor Cells, Vascular Function, and Cardiovascular Risk

    Jonathan M. Hill;Gloria Zalos;Julian P. J. Halcox;William H. Schenke

  • Requirement for Generation of H2O2 for Platelet-Derived Growth Factor Signal Transduction

    Maitrayee Sundaresan;Zu Xi Yu;Victor J. Ferrans;Kaikobad Irani

  • Signal transduction by reactive oxygen species

    Toren Finkel

  • Cellular mechanisms and physiological consequences of redox-dependent signalling

    Kira M. Holmström;Toren Finkel

  • Mitogenic Signaling Mediated by Oxidants in Ras-Transformed Fibroblasts

    Kaikobad Irani;Yong Xia;Jay L. Zweier;Steven J. Sollott

  • 53BP1 Inhibits Homologous Recombination in Brca1-Deficient Cells by Blocking Resection of DNA Breaks

    Samuel F. Bunting;Elsa Callén;Nancy Wong;Hua Tang Chen

  • Oxidant signals and oxidative stress.

    Toren Finkel

  • Recent progress in the biology and physiology of sirtuins

    Toren Finkel;Chu Xia Deng;Raul Mostoslavsky

  • A role for the NAD-dependent deacetylase Sirt1 in the regulation of autophagy

    In Hye Lee;Liu Cao;Raul Mostoslavsky;David B. Lombard

  • A role for the mitochondrial deacetylase Sirt3 in regulating energy homeostasis

    Bong-Hyun Ahn;Hyun-Seok Kim;Shiwei Song;In Hye Lee

  • Oxygen radicals and signaling

    Toren Finkel

  • The Mitochondrial Basis of Aging

    Nuo Sun;Richard J. Youle;Toren Finkel

  • The common biology of cancer and ageing

    Toren Finkel;Manuel Serrano;Maria A. Blasco

  • SIRT1 Functionally Interacts with the Metabolic Regulator and Transcriptional Coactivator PGC-1α

    Shino Nemoto;Maria M. Fergusson;Toren Finkel

  • Redox Regulation of Forkhead Proteins Through a p66shc-Dependent Signaling Pathway

    Shino Nemoto;Toren Finkel

  • Human mesenchymal stem cells exert potent antitumorigenic effects in a model of Kaposi's sarcoma

    Aarif Y. Khakoo;Aarif Y. Khakoo;Shibani Pati;Stasia A. Anderson;William Reid

Frequent Co-Authors

Jie Liu
Jie Liu National Institutes of Health
Stephen E. Epstein
Stephen E. Epstein MedStar Health
Elizabeth Murphy
Elizabeth Murphy National Heart Lung and Blood Institute
Victor J. Ferrans
Victor J. Ferrans National Institutes of Health
Chu-Xia Deng
Chu-Xia Deng University of Macau
Charles J. Lowenstein
Charles J. Lowenstein Johns Hopkins University School of Medicine
Evelina Gatti
Evelina Gatti Aix-Marseille University
Oksana Gavrilova
Oksana Gavrilova National Institutes of Health
Kazuyo Takeda
Kazuyo Takeda US Food and Drug Administration

If you think any of the details on this page are incorrect, let us know.

Report an issue

We appreciate your kind effort to assist us to improve this page, it would be helpful providing us with as much detail as possible in the text box below:

Best Scientists Citing Toren Finkel

Trending Scientists

Recently Published Articles