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Chu-Xia Deng

Chu-Xia Deng

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Biology and Biochemistry
China
2026
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Medicine
China
2026

D-Index & Metrics

Biology and Biochemistry

D-Index
154
Citations
82000
World Ranking
156
National Ranking
1

Medicine

D-Index
154
Citations
81912
World Ranking
1009
National Ranking
8

Research.com Recognitions

  • 2026 - Research.com Biology and Biochemistry in China Leader Award
  • 2026 - Research.com Medicine in China Leader Award
  • 2025 - Research.com Biology and Biochemistry in China Leader Award
  • 2025 - Research.com Medicine in China Leader Award
  • 2023 - Research.com Biology and Biochemistry in China Leader Award
  • 2022 - Research.com Biology and Biochemistry in China Leader Award
  • 2011 - Fellow of the American Association for the Advancement of Science (AAAS)

Overview

Chu-Xia Deng is affiliated with the University of Macau in China and has a research focus primarily situated within the fields of Biochemistry, Genetics and Molecular Biology, as well as Medicine. Their body of work spans multiple subfields, including Molecular Biology, Oncology, Cancer Research, Biomedical Engineering, and Immunology.

The scientist's main topics of research cover a range of cancer-related themes, such as Cancer Cells and Metastasis, Cancer Genomics and Diagnostics, Cancer-related Molecular Pathways, 3D Printing in Biomedical Research, RNA modifications and cancer, Cancer Immunotherapy and Biomarkers, and Cancer-related molecular mechanisms research.

Chu-Xia Deng has published extensively in several prominent scientific journals. The frequent venues for their publications include:

  • International Journal of Biological Sciences
  • Nature Communications
  • Advanced Science
  • Theranostics
  • Cancer Research

Recent notable papers authored or coauthored by Chu-Xia Deng include:

  • "Tumor heterogeneity reshapes the tumor microenvironment to influence drug resistance" (2022) published in International Journal of Biological Sciences
  • "Patient-Derived Organoids Can Guide Personalized-Therapies for Patients with Advanced Breast Cancer" (2021) published in Advanced Science
  • "Oxygen-Enriched Metal-Phenolic X-Ray Nanoprocessor for Cancer Radio-Radiodynamic Therapy in Combination with Checkpoint Blockade Immunotherapy" (2020) published in Advanced Science
  • "Cisplatin prevents breast cancer metastasis through blocking early EMT and retards cancer growth together with paclitaxel" (2020) published in Theranostics
  • "NOTCH1 activation compensates BRCA1 deficiency and promotes triple-negative breast cancer formation" (2020) published in Nature Communications

The scientist's collaborative network features frequent coauthors, reflecting ongoing research partnerships. These frequent collaborators include Josh Haipeng Lei, Xiaoling Xu, Kai Miao, Heng Sun, and Haitao Wang.

Chu-Xia Deng was recognized as a Fellow of the American Association for the Advancement of Science (AAAS) in 2011.

Best Publications

  • Mice Lacking p21CIP1/WAF1 undergo normal development, but are defective in G1 checkpoint control

    Chuxia Deng;Chuxia Deng;Pumin Zhang;J. Wade Harper;Stephen J. Elledge;Stephen J. Elledge

  • TGF-β and BMP Signaling in Osteoblast Differentiation and Bone Formation

    Guiqian Chen;Chuxia Deng;Yi-Ping Li

  • 53BP1 Inhibits Homologous Recombination in Brca1-Deficient Cells by Blocking Resection of DNA Breaks

    Samuel F. Bunting;Elsa Callén;Nancy Wong;Hua Tang Chen

  • Recent progress in the biology and physiology of sirtuins

    Toren Finkel;Chu Xia Deng;Raul Mostoslavsky

  • A role for the mitochondrial deacetylase Sirt3 in regulating energy homeostasis

    Bong-Hyun Ahn;Hyun-Seok Kim;Shiwei Song;In Hye Lee

  • Edg-1, the G protein–coupled receptor for sphingosine-1-phosphate, is essential for vascular maturation

    Yujing Liu;Ryuichi Wada;Tadashi Yamashita;Yide Mi

  • Fibroblast Growth Factor Receptor 3 Is a Negative Regulator of Bone Growth

    Chuxia Deng;Anthony Wynshaw-Boris;Fen Zhou;Ann Kuo

  • Mice lacking Smad3 show accelerated wound healing and an impaired local inflammatory response.

    Gillian S. Ashcroft;Xiao Yang;Adam B. Glick;Michael Weinstein

  • Targeted disruption of SMAD3 results in impaired mucosal immunity and diminished T cell responsiveness to TGF-β

    Xiao Yang;John J. Letterio;Robert J. Lechleider;Lin Chen

  • Transforming properties of YAP, a candidate oncogene on the chromosome 11q22 amplicon

    Michael Overholtzer;Jianmin Zhang;Gromoslaw A. Smolen;Beth Muir

  • Centrosome amplification and a defective G2-M cell cycle checkpoint induce genetic instability in BRCA1 exon 11 isoform-deficient cells.

    Xiaoling Xu;Zoë Weaver;Steven P Linke;Cuiling Li

  • Impaired DNA damage response, genome instability, and tumorigenesis in SIRT1 mutant mice.

    Rui Hong Wang;Kundan Sengupta;Cuiling Li;Hyun Seok Kim

  • Murine FGFR-1 is required for early postimplantation growth and axial organization.

    C X Deng;A Wynshaw-Boris;M M Shen;C Daugherty

  • Conditional mutation of Brca1 in mammary epithelial cells results in blunted ductal morphogenesis and tumour formation.

    Xiaoling Xu;Kay Uwe Wagner;Denise Larson;Zoë Weaver

  • Perilipin ablation results in a lean mouse with aberrant adipocyte lipolysis, enhanced leptin production, and resistance to diet-induced obesity

    J. T. Tansey;C. Sztalryd;J. Gruia-Gray;D. L. Roush

  • SIRT3 Is a Mitochondria-Localized Tumor Suppressor Required for Maintenance of Mitochondrial Integrity and Metabolism during Stress

    Hyun Seok Kim;Krish Patel;Kristi Muldoon-Jacobs;Kheem S. Bisht

  • TGF-β/Smad3 Signals Repress Chondrocyte Hypertrophic Differentiation and Are Required for Maintaining Articular Cartilage

    Xiao Yang;Lin Chen;Xiaoling Xu;Cuiling Li

  • Docking of Axonal Mitochondria by Syntaphilin Controls Their Mobility and Affects Short-Term Facilitation

    Jian-Sheng Kang;Jin-Hua Tian;Ping-Yue Pan;Ping-Yue Pan;Philip Zald

  • A role of SMAD4 in iron metabolism through the positive regulation of hepcidin expression

    Rui Hong Wang;Cuiling Li;Xiaoling Xu;Yin Zheng

  • BRCA1: cell cycle checkpoint, genetic instability, DNA damage response and cancer evolution

    Chu-Xia Deng

Frequent Co-Authors

Xiaoling Xu
Xiaoling Xu University of Macau
Cuiling Li
Cuiling Li National Institutes of Health
Haitao Wang
Haitao Wang Nankai University
Jürgen Wess
Jürgen Wess National Institutes of Health
Xiao Yang
Xiao Yang Shanghai Jiao Tong University
Anthony Wynshaw-Boris
Anthony Wynshaw-Boris Case Western Reserve University
Philip Leder
Philip Leder Harvard University
Oksana Gavrilova
Oksana Gavrilova National Institutes of Health
Rui P. Martins
Rui P. Martins University of Macau
Thomas Ried
Thomas Ried National Institutes of Health

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