Xiaoling Xu

Overview

Best Publications

• 53BP1 Inhibits Homologous Recombination in Brca1-Deficient Cells by Blocking Resection of DNA Breaks

  Samuel F. Bunting;Elsa Callén;Nancy Wong;Hua Tang Chen

  1892
  Citations

• Centrosome amplification and a defective G2-M cell cycle checkpoint induce genetic instability in BRCA1 exon 11 isoform-deficient cells.

  Xiaoling Xu;Zoë Weaver;Steven P Linke;Cuiling Li

  1017
  Citations

• Impaired DNA damage response, genome instability, and tumorigenesis in SIRT1 mutant mice.

  Rui Hong Wang;Kundan Sengupta;Cuiling Li;Hyun Seok Kim

  932
  Citations

• Conditional mutation of Brca1 in mammary epithelial cells results in blunted ductal morphogenesis and tumour formation.

  Xiaoling Xu;Kay Uwe Wagner;Denise Larson;Zoë Weaver

  919
  Citations

• TGF-β/Smad3 Signals Repress Chondrocyte Hypertrophic Differentiation and Are Required for Maintaining Articular Cartilage

  Xiao Yang;Lin Chen;Xiaoling Xu;Cuiling Li

  770
  Citations

• A role of SMAD4 in iron metabolism through the positive regulation of hepcidin expression

  Rui Hong Wang;Cuiling Li;Xiaoling Xu;Yin Zheng

  756
  Citations

• Fibroblast growth factor receptor 2 (FGFR2)-mediated reciprocal regulation loop between FGF8 and FGF10 is essential for limb induction.

  Xiaoling Xu;Michael Weinstein;Cuiling Li;Michael Naski

  672
  Citations

• Silencing of unsynapsed meiotic chromosomes in the mouse.

  James M A Turner;Shantha K Mahadevaiah;Oscar Fernandez-Capetillo;André Nussenzweig

  613
  Citations

• FGFR-3 and FGFR-4 function cooperatively to direct alveogenesis in the murine lung

  Michael Weinstein;Xiaoling Xu;Kyoji Ohyama;Chu-Xia Deng

  570
  Citations

• SIRT2 Maintains Genome Integrity and Suppresses Tumorigenesis through Regulating APC/C Activity

  Hyun Seok Kim;Athanassios Vassilopoulos;Rui Hong Wang;Tyler Lahusen

  569
  Citations

• Hepatic-Specific Disruption of SIRT6 in Mice Results in Fatty Liver Formation Due to Enhanced Glycolysis and Triglyceride Synthesis

  Hyun Seok Kim;Cuiying Xiao;Rui Hong Wang;Tyler Lahusen

  527
  Citations

• Bmi1 regulates mitochondrial function and the DNA damage response pathway

  Jie Liu;Liu Cao;Jichun Chen;Shiwei Song

  514
  Citations

• SIRT4 Has Tumor-Suppressive Activity and Regulates the Cellular Metabolic Response to DNA Damage by Inhibiting Mitochondrial Glutamine Metabolism

  Seung Min Jeong;Cuiying Xiao;Lydia W.S. Finley;Tyler Lahusen

  487
  Citations

• Angiogenesis defects and mesenchymal apoptosis in mice lacking SMAD5

  Xiao Yang;Lucio H. Castilla;Xiaoling Xu;Cuiling Li

  468
  Citations

• BRCA1, Histone H2AX Phosphorylation, and Male Meiotic Sex Chromosome Inactivation

  James M.A. Turner;Olga Aprelikova;Xiaoling Xu;Ruihong Wang

  454
  Citations

• The tumor suppressor SMAD4/DPC4 is essential for epiblast proliferation and mesoderm induction in mice

  Xiao Yang;Cuiling Li;Xiaoling Xu;Chuxia Deng

  438
  Citations

• Genetic interactions between tumor suppressors Brca1 and p53 in apoptosis, cell cycle and tumorigenesis.

  Xiaoling Xu;Wenhui Qiao;Steven P. Linke;Liu Cao

  427
  Citations

• A targeted disruption of the murine Brca1 gene causes γ-irradiation hypersensitivity and genetic instability

  Shan Xiang Shen;Zoë Weaver;Xiaoling Xu;Cuiling Li

  425
  Citations

• Interplay among BRCA1, SIRT1, and Survivin during BRCA1-associated tumorigenesis.

  Rui Hong Wang;Yin Zheng;Hyun Seok Kim;Xiaoling Xu

  423
  Citations

• Failure of egg cylinder elongation and mesoderm induction in mouse embryos lacking the tumor suppressor smad2.

  Michael Weinstein;Xiao Yang;Cuiling Li;Xiaoling Xu

  396
  Citations