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D-Index & Metrics

Biology and Biochemistry

D-Index
65
Citations
11416
World Ranking
9403
National Ranking
246

Overview

Robert C. Tuckey is affiliated with the University of Western Australia in Australia. Their research primarily spans the fields of Medicine and Biochemistry, Genetics and Molecular Biology, with a focus on several subfields including Pathology and Forensic Medicine, Endocrinology, Diabetes and Metabolism, Genetics, Dermatology, and Immunology.

Their scientific contributions cover a variety of topics, notably:

  • Vitamin D Research Studies
  • Estrogen and related hormone effects
  • Hormonal Regulation and Hypertension
  • Psoriasis: Treatment and Pathogenesis
  • Adrenal Hormones and Disorders
  • Skin Protection and Aging
  • Vitamin C and Antioxidants Research

Robert C. Tuckey has coauthored numerous publications with several frequent collaborators. These include:

  • Andrzej Słomiński
  • Tae-Kang Kim
  • Zorica Janjetović
  • Radomir M. Slominski
  • Anton M. Jetten

Their research has appeared in a selection of journals, with repeated contributions to the following venues:

  • Journal of Investigative Dermatology
  • International Journal of Molecular Sciences
  • The Journal of Steroid Biochemistry and Molecular Biology
  • Journal of the Endocrine Society
  • Scientific Reports

Highlighted recent papers by Robert C. Tuckey include:

  • Biological Effects of CYP11A1-Derived Vitamin D and Lumisterol Metabolites in the Skin, 2024, Journal of Investigative Dermatology
  • Photoprotective Properties of Vitamin D and Lumisterol Hydroxyderivatives, 2020, Cell Biochemistry and Biophysics
  • Extra-adrenal glucocorticoid biosynthesis: implications for autoimmune and inflammatory disorders, 2020, Genes and Immunity
  • The significance of CYP11A1 expression in skin physiology and pathology, 2021, Molecular and Cellular Endocrinology
  • Vitamin D and lumisterol derivatives can act on liver X receptors (LXRs), 2021, Scientific Reports

Best Publications

  • Steroidogenesis in the skin: Implications for local immune functions

    Andrzej Slominski;Blazej Zbytek;Georgios Nikolakis;Pulak R. Manna

  • Progesterone synthesis by the human placenta

    Robert C. Tuckey

  • Differential expression of HPA axis homolog in the skin.

    Andrzej Slominski;Jacobo Wortsman;Robert C. Tuckey;Ralf Paus

  • Novel activities of CYP11A1 and their potential physiological significance

    Andrzej T. Slominski;Wei Li;Tae Kang Kim;Igor Semak

  • In vivo evidence for a novel pathway of vitamin D3 metabolism initiated by P450scc and modified by CYP27B1

    Andrzej T. Slominski;Tae Kang Kim;Haleem Z. Shehabi;Igor Semak

  • A novel pathway for sequential transformation of 7‐dehydrocholesterol and expression of the P450scc system in mammalian skin

    Andrzej Slominski;Jordan Zjawiony;Jacobo Wortsman;Igor Semak

  • RORα and ROR γ are expressed in human skin and serve as receptors for endogenously produced noncalcemic 20-hydroxy- and 20,23-dihydroxyvitamin D

    Andrzej T. Slominski;Tae Kang Kim;Yukimasa Takeda;Zorica Janjetovic

  • Cutaneous hypothalamic-pituitary-adrenal axis homolog: regulation by ultraviolet radiation.

    Cezary Skobowiat;John C. Dowdy;Robert M Sayre;Robert C Tuckey

  • Detection of novel CYP11A1-derived secosteroids in the human epidermis and serum and pig adrenal gland

    Andrzej T. Slominski;Andrzej T. Slominski;Tae Kang Kim;Wei Li;Arnold Postlethwaite;Arnold Postlethwaite

  • The serum vitamin D metabolome: What we know and what is still to discover.

    Robert C. Tuckey;Chloe Y.S. Cheng;Andrzej T. Slominski

  • On the role of skin in the regulation of local and systemic steroidogenic activities

    Andrzej T. Slominski;Pulak R. Manna;Robert C. Tuckey

  • The cytochrome P450scc system opens an alternate pathway of vitamin D3 metabolism

    Andrzej Slominski;Igor Semak;Jordan Zjawiony;Jacobo Wortsman

  • The role of CYP11A1 in the production of vitamin D metabolites and their role in the regulation of epidermal functions.

    Andrzej T. Slominski;Tae Kang Kim;Wei Li;Ae-Kyung Yi

  • Products of vitamin D3 or 7-dehydrocholesterol metabolism by cytochrome P450scc show anti-leukemia effects, having low or absent calcemic activity.

    Andrzej T. Slominski;Zorica Janjetovic;Brian E. Fuller;Michal A. Zmijewski

  • Endogenously produced nonclassical vitamin D hydroxy-metabolites act as "biased" agonists on VDR and inverse agonists on RORα and RORγ

    Andrzej T. Slominski;Andrzej T. Slominski;Tae Kang Kim;Judith V. Hobrath;Allen S.W. Oak

  • 20-Hydroxycholecalciferol, Product of Vitamin D3 Hydroxylation by P450scc, Decreases NF-κB Activity by Increasing IκBα Levels in Human Keratinocytes

    Zorica Janjetovic;Michal A. Zmijewski;Robert C. Tuckey;Damon A. DeLeon

  • Pathways and products for the metabolism of vitamin D3 by cytochrome P450scc

    Robert C. Tuckey;Wei Li;Jordan K. Zjawiony;Michal A. Zmijewski

  • 20-Hydroxyvitamin D2 is a noncalcemic analog of vitamin D with potent antiproliferative and prodifferentiation activities in normal and malignant cells

    Andrzej T. Slominski;Tae Kang Kim;Zorica Janjetovic;Robert C. Tuckey

  • Vitamin D signaling and melanoma: role of vitamin D and its receptors in melanoma progression and management

    Andrzej T Slominski;Anna A Brożyna;Anna A Brożyna;Michal A Zmijewski;Wojciech Jóźwicki;Wojciech Jóźwicki

  • 20,23-dihydroxyvitamin D3, novel P450scc product, stimulates differentiation and inhibits proliferation and NF-κB activity in human keratinocytes

    Zorica Janjetovic;Robert C. Tuckey;Minh N. Nguyen;Edwin M. Thorpe

Frequent Co-Authors

Andrzej Slominski
Andrzej Slominski University of Alabama at Birmingham
Wei Li
Wei Li University of Tennessee Health Science Center
Arnold E. Postlethwaite
Arnold E. Postlethwaite University of Tennessee Health Science Center
Jordan K. Zjawiony
Jordan K. Zjawiony University of Mississippi
Anton M. Jetten
Anton M. Jetten National Institutes of Health
Duane D. Miller
Duane D. Miller University of Tennessee Health Science Center
Jacobo Wortsman
Jacobo Wortsman Southern Illinois University School of Medicine
Michael F. Holick
Michael F. Holick Boston University
Chander Raman
Chander Raman University of Alabama at Birmingham
Craig A. Elmets
Craig A. Elmets University of Alabama at Birmingham

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