Alexey V. Pshezhetsky

Overview

Best Publications

• A genome-wide association study identifies novel risk loci for type 2 diabetes

  Robert Sladek;Ghislain Rocheleau;Johan Rung;Christian Dina

  3694
  Citations

• De Novo Mutations in Moderate or Severe Intellectual Disability

  Fadi F. Hamdan;Myriam Srour;Jose-Mario Capo-Chichi;Hussein Daoud

  429
  Citations

• Cloning, expression and chromosomal mapping of human lysosomal sialidase and characterization of mutations in sialidosis.

  Alexey V. Pshezhetsky;Catherine Richard;Lorraine Michaud;Suleiman Igdoura

  273
  Citations

• Neu1 desialylation of sialyl α-2,3-linked β-galactosyl residues of TOLL-like receptor 4 is essential for receptor activation and cellular signaling.

  Schammim Ray Amith;Preethi Jayanth;Susan Franchuk;Trisha Finlay

  221
  Citations

• Monocyte differentiation up-regulates the expression of the lysosomal sialidase, Neu1, and triggers its targeting to the plasma membrane via major histocompatibility complex class II-positive compartments.

  Feng Liang;Volkan Seyrantepe;Karine Landry;Rasheed Ahmad

  197
  Citations

• Neu4, a novel human lysosomal lumen sialidase, confers normal phenotype to sialidosis and galactosialidosis cells

  Volkan Seyrantepe;Karine Landry;Stéphanie Trudel;Jacob A. Hassan

  191
  Citations

• Molecular pathology of NEU1 gene in sialidosis

  Volkan Seyrantepe;Helena Poupetova;Roseline Froissart;Marie‐Thérèse Zabot

  190
  Citations

• Lysosomal sialidase (neuraminidase-1) is targeted to the cell surface in a multiprotein complex that facilitates elastic fiber assembly.

  Aleksander Hinek;Alexey V. Pshezhetsky;Mark von Itzstein;Barry Starcher

  185
  Citations

• Clinical and genetic spectrum of Sanfilippo type C (MPS IIIC) disease in The Netherlands.

  G.J. Ruijter;M.J. Valstar;J.M. van de Kamp;R.M. van der Helm

  180
  Citations

• Lysosomal multienzyme complex: biochemistry, genetics, and molecular pathophysiology.

  Alexey V Pshezhetsky;Mila Ashmarina

  176
  Citations

• Carboxylesterase 3 (EC 3.1.1.1) is a major adipocyte lipase.

  Krishnakant G. Soni;Richard Lehner;Pavel Metalnikov;Paul O'Donnell

  170
  Citations

• Association of N-Acetylgalactosamine-6-sulfate Sulfatase with the Multienzyme Lysosomal Complex of β-Galactosidase, Cathepsin A, and Neuraminidase POSSIBLE IMPLICATION FOR INTRALYSOSOMAL CATABOLISM OF KERATAN SULFATE

  Alexey V. Pshezhetsky;Michel Potier

  152
  Citations

• Dependence of pathogen molecule-induced Toll-like receptor activation and cell function on Neu1 sialidase

  Schammim Ray Amith;Preethi Jayanth;Susan Franchuk;Sarah Siddiqui

  149
  Citations

• Proteome Analysis and Functional Expression Identify Mortalin as an Antiapoptotic Gene Induced by Elevation of [Na+]i/[K+]i Ratio in Cultured Vascular Smooth Muscle Cells

  Sebastien Taurin;Volkan Seyrantepe;Sergei N. Orlov;Tammy-Lynn Tremblay

  148
  Citations

• Caspase-3 activation triggers extracellular cathepsin L release and endorepellin proteolysis.

  Jean-François Cailhier;Isabelle Sirois;Patrick Laplante;Stéphanie Lepage

  148
  Citations

• Neuroinflammation, mitochondrial defects and neurodegeneration in mucopolysaccharidosis III type C mouse model

  Carla Martins;Helena Hůlková;Larbi Dridi;Virginie Dormoy-Raclet

  139
  Citations

• Mutations in TMEM76 Cause Mucopolysaccharidosis IIIC (Sanfilippo C Syndrome)

  Martin Hřebíček;Lenka Mrázová;Volkan Seyrantepe;Stéphanie Durand

  135
  Citations

• Enzymes entrapped in reversed micelles of surfactants in organic solvents: A theoretical treatment of the catalytic activity regulation

  Alexander Victorovich Kabanov;A. V. Levashov;N. L. Klyachko;S. N. Namyotkin

  133
  Citations

• Intracellular distribution of lysosomal sialidase is controlled by the internalization signal in its cytoplasmic tail.

  Kiven E. Lukong;Volkan Seyrantepe;Karine Landry;Stéphanie Trudel

  130
  Citations

• Lysosomal Sialidase (Neuraminidase-1) Is Targeted to the Cell Surface in a Multiprotein Complex That Facilitates Elastic

  Aleksander Hinek;Alexey V. Pshezhetsky;Mark von Itzstein;Barry Starcher

  0
  Citations