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Aleksander Hinek

Aleksander Hinek

D-Index & Metrics

Biology and Biochemistry

D-Index
59
Citations
10120
World Ranking
12776
National Ranking
436

Overview

Aleksander Hinek is affiliated with the University of Toronto in Canada and has an extensive research portfolio primarily focused in the fields of Medicine and Biochemistry, Genetics and Molecular Biology. Their work spans subfields including Cardiology and Cardiovascular Medicine, Molecular Biology, Cancer Research, Rehabilitation, and Physiology.

Their research addresses a range of topics with a notable emphasis on Wound Healing and Treatments. Other main topics covered by Aleksander Hinek include Cardiac Health and Mental Health, Heart Rate Variability and Autonomic Control, Biofield Effects and Biophysics, Antiplatelet Therapy and Cardiovascular Diseases, Acute Myocardial Infarction Research, and Coronary Interventions and Diagnostics.

Frequent co-authors collaborating with Aleksander Hinek comprise Shuai Mao, Minzhou Zhang, Shawn Loder, Thomas F. Mitts, and Yubin Liang.

In terms of publication venues, their research has appeared in Plastic & Reconstructive Surgery Global Open, Cardiovascular Drugs and Therapy, Science Advances, American Journal of Physiology-Cell Physiology, and ESC Heart Failure.

Recent papers authored or co-authored by Aleksander Hinek include:

  • Beneficial Effects of Baduanjin Exercise on Left Ventricular Remodelling in Patients after Acute Myocardial Infarction: an Exploratory Clinical Trial and Proteomic Analysis (2020, Cardiovascular Drugs and Therapy)
  • Efficacy of Sodium Tanshinone IIA Sulfonate in Patients with Non-ST Elevation Acute Coronary Syndrome Undergoing Percutaneous Coronary Intervention: Results from a Multicentre, Controlled, Randomized Trial (2020, Cardiovascular Drugs and Therapy)
  • Fat-1 transgenic mice rich in endogenous omega-3 fatty acids are protected from lipopolysaccharide-induced cardiac dysfunction (2021, ESC Heart Failure)
  • N-acetylneuraminate pyruvate lyase controls sialylation of muscle glycoproteins essential for muscle regeneration and function (2023, Science Advances)
  • Potential Mechanism of Dermal Wound Treatment With Preparations From the Skin Gel of Arabian Gulf Catfish: A Unique Furan Fatty Acid (F6) and Cholesta-3,5-Diene (S5) Recruit Neutrophils and Fibroblasts to Promote Wound Healing (2020, Frontiers in Pharmacology)

Best Publications

  • Fibulin-5/DANCE is essential for elastogenesis in vivo

    Tomoyuki Nakamura;Pilar Ruiz Lozano;Yasuhiro Ikeda;Yoshitaka Iwanaga

  • The Elastin Receptor: A Galactoside-Binding Protein

    Aleksander Hinek;David S. Wrenn;Robert P. Mecham;Samuel H. Barondes

  • Signaling Pathways Transduced through the Elastin Receptor Facilitate Proliferation of Arterial Smooth Muscle Cells

    Satsuki Mochizuki;Bertrand Brassart;Aleksander Hinek

  • Elastic fibres and vascular structure in hypertension

    Silvia M. Arribas;Aleksander Hinek;M. Carmen González

  • Elastin binds to a multifunctional 67-kilodalton peripheral membrane protein

    Robert P. Mecham;Aleksander Hinek;Ruth Entwistle;David S. Wrenn

  • The 67-kDa Enzymatically Inactive Alternatively Spliced Variant of β-Galactosidase Is Identical to the Elastin/Laminin-binding Protein

    Salvatore Privitera;Catherine A. Prody;John W. Callahan;Aleksander Hinek

  • 67-kD elastin-binding protein is a protective companion of extracellular insoluble elastin and intracellular tropoelastin.

    A Hinek;M Rabinovitch

  • Impaired Elastogenesis in Hurler Disease: Dermatan Sulfate Accumulation Linked to Deficiency in Elastin-Binding Protein and Elastic Fiber Assembly

    Aleksander Hinek;Sarah E. Wilson

  • Connection between elastin haploinsufficiency and increased cell proliferation in patients with supravalvular aortic stenosis and Williams-Beuren syndrome.

    Zsolt Urbán;Sheila Riazi;Thomas L. Seidl;Jodi Katahira

  • The 67-kD elastin/laminin-binding protein is related to an enzymatically inactive, alternatively spliced form of beta-galactosidase.

    A. Hinek;M. Rabinovitch;F. Keeley;Yuko Okamura-Oho

  • Actin filaments participate in the relocalization of phosphatidylinositol3-kinase to glucose transporter-containing compartments and in the stimulation of glucose uptake in 3T3-L1 adipocytes

    Qinghua Wang;Philip J. Bilan;Theodoros Tsakiridis;Aleksander Hinek

  • Maintenance of chondroitin sulfation balance by chondroitin-4-sulfotransferase 1 is required for chondrocyte development and growth factor signaling during cartilage morphogenesis

    Michael Klüppel;Thomas N. Wight;Christina Chan;Aleksander Hinek

  • Impaired elastin fiber assembly related to reduced 67-kD elastin-binding protein in fetal lamb ductus arteriosus and in cultured aortic smooth muscle cells treated with chondroitin sulfate.

    A Hinek;R P Mecham;F Keeley;M Rabinovitch

  • Lysosomal sialidase (neuraminidase-1) is targeted to the cell surface in a multiprotein complex that facilitates elastic fiber assembly.

    Aleksander Hinek;Alexey V. Pshezhetsky;Mark von Itzstein;Barry Starcher

  • Decreased Elastin Deposition and High Proliferation of Fibroblasts from Costello Syndrome Are Related to Functional Deficiency in the 67-kD Elastin-Binding Protein

    Aleksander Hinek;Adam C. Smith;Eva Maria Cutiongco;John W. Callahan

  • The endogenous vascular elastase that governs development and progression of monocrotaline-induced pulmonary hypertension in rats is a novel enzyme related to the serine proteinase adipsin.

    Li Zhu;Dennis Wigle;Aleksander Hinek;Jun Kobayashi

  • Changes in elastin, elastin binding protein and versican in alveoli in chronic obstructive pulmonary disease.

    Mervyn J Merrilees;Pamela S T Ching;Brent Beaumont;Aleksander Hinek

  • The Elastin Receptor Complex Transduces Signals through the Catalytic Activity of Its Neu-1 Subunit

    Laurent Duca;Charlotte Blanchevoye;Benoît Cantarelli;Christelle Ghoneim

  • Vascular smooth muscle cell detachment from elastin and migration through elastic laminae is promoted by chondroitin sulfate-induced “shedding” of the 67-kDa cell surface elastin binding protein

    Aleksander Hinek;Jennifer Boyle;Marlene Rabinovitch

  • Lysosomal Sialidase (Neuraminidase-1) Is Targeted to the Cell Surface in a Multiprotein Complex That Facilitates Elastic

    Aleksander Hinek;Alexey V. Pshezhetsky;Mark von Itzstein;Barry Starcher

Frequent Co-Authors

David Chitayat
David Chitayat University of Toronto
Alexey V. Pshezhetsky
Alexey V. Pshezhetsky University of Montreal
Marlene Rabinovitch
Marlene Rabinovitch Stanford University
Peter Liu
Peter Liu University of Ottawa
Thomas N. Wight
Thomas N. Wight Virginia Mason Medical Center
Robert P. Mecham
Robert P. Mecham Washington University in St. Louis
Joan C. Marini
Joan C. Marini National Institutes of Health
William L. Stanford
William L. Stanford Ottawa Hospital
James T. Rutka
James T. Rutka University of Toronto
Rosanna Weksberg
Rosanna Weksberg University of Toronto

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