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Biology and Biochemistry

D-Index
75
Citations
16394
World Ranking
5429
National Ranking
419

Overview

Cay M. Kielty is affiliated with the Wellcome Centre for Cell-Matrix Research in the United Kingdom. Their research contributions primarily intersect the fields of medicine, immunology, and microbiology, with particular focuses in several subfields such as immunology, immunology and allergy, pulmonary and respiratory medicine, hematology, and cancer research.

The scientist's work covers main topics including cell adhesion molecules research, phagocytosis and immune regulation, the reproductive system and pregnancy, blood properties and coagulation, platelet disorders and treatments, and protease and inhibitor mechanisms.

Frequent publication venues for their research include the Journal of Biological Chemistry and Matrix Biology, where they have multiple papers published.

  • Inter-α-inhibitor heavy chain-1 has an integrin-like 3D structure mediating immune regulatory activities and matrix stabilization during ovulation, 2020, Journal of Biological Chemistry
  • Latent TGFβ complexes are transglutaminase cross-linked to fibrillin to facilitate TGFβ activation, 2022, Matrix Biology
  • Author Index, 2020, Journal of Biological Chemistry

Among frequent co-authors partnering with Cay M. Kielty are Jan J. Enghild, Clair Baldock, Caroline M. Milner, David C. Briggs, and Alex Langford-Smith.

Best Publications

  • The Collagen Family: Structure, Assembly, and Organization in the Extracellular Matrix

    Cay M. Kielty;Michael E. Grant

  • The molecular genetics of Marfan syndrome and related disorders

    Peter N. Robinson;E. Arteaga-Solis;C. Baldock;G. Collod-Béroud

  • Missense mutations in COL8A2, the gene encoding the α2 chain of type VIII collagen, cause two forms of corneal endothelial dystrophy

    Susmito Biswas;Francis L. Munier;Jill Yardley;Niki Hart-Holden

  • Elastic fibres in health and disease.

    Andrew K. Baldwin;Andreja Simpson;Ruth Steer;Stuart A. Cain

  • Vascular endothelial growth factor can signal through platelet-derived growth factor receptors

    Stephen G. Ball;C. Adrian Shuttleworth;Cay M. Kielty

  • Fibronectin Regulates Latent Transforming Growth Factor-β (TGFβ) by Controlling Matrix Assembly of Latent TGFβ-binding Protein-1 *

    Sarah L. Dallas;Pitchumani Sivakumar;Carolyn J.P. Jones;Qian Chen

  • Fibrillin-1 regulates the bioavailability of TGFβ1

    Shazia S. Chaudhry;Shazia S. Chaudhry;Stuart A. Cain;Amanda Morgan;Sarah L. Dallas

  • Fibrillin degradation by matrix metalloproteinases: implications for connective tissue remodelling

    J L Ashworth;G Murphy;M J Rock;M J Sherratt

  • PCL-PU composite vascular scaffold production for vascular tissue engineering: attachment, proliferation and bioactivity of human vascular endothelial cells.

    Matthew Richard Williamson;Richard Black;Cay Kielty

  • Direct cell contact influences bone marrow mesenchymal stem cell fate.

    Stephen G Ball;Adrian C Shuttleworth;Cay M Kielty

  • Mesenchymal stem cell migration is regulated by fibronectin through α5β1-integrin-mediated activation of PDGFR-β and potentiation of growth factor signals

    Jennifer Veevers-Lowe;Stephen G. Ball;Adrian Shuttleworth;Cay M. Kielty

  • Type VI collagen microfibrils: evidence for a structural association with hyaluronan.

    C M Kielty;S P Whittaker;M E Grant;C A Shuttleworth

  • A mutation in FBN1 disrupts profibrillin processing and results in isolated skeletal features of the Marfan syndrome.

    Dianna M Milewicz;Jami Grossfield;Shi Nian Cao;Cay Kielty

  • Fibrillin microfibrils are reduced in skin exhibiting striae distensae

    R. E B Watson;E. J. Parry;J. D. Humphries;C. J P Jones

  • Cell Adhesion to Fibrillin-1 Molecules and Microfibrils Is Mediated by α5β1 and αvβ3 Integrins

    Daniel.V. Bax;Sarah E. Bernard;Amanda Lomas;Amanda Morgan

  • An Elastin Gene Mutation Producing Abnormal Tropoelastin and Abnormal Elastic Fibres in a Patient with Autosomal Dominant Cutis Laxa

    Mayada Tassabehji;Kay Metcalfe;Jane Hurst;Gillian S. Ashcroft

  • Type X collagen, a product of hypertrophic chondrocytes

    C M Kielty;A P L Kwan;D F Holmes;S L Schor

  • Fibrillin-rich microfibrils are reduced in photoaged skin. Distribution at the dermal-epidermal junction.

    Rachel E.B. Watson;Christopher E.M. Griffiths;Nicholas M. Craven;C. Adrian Shuttleworth

  • Mutation of the signal peptide region of the bicistronic gene DSPP affects translocation to the endoplasmic reticulum and results in defective dentine biomineralization

    M. Helen Rajpar;Martin J. Koch;Robin M. Davies;Kieran T. Mellody

  • Mesenchymal stem cells and neovascularization: role of platelet-derived growth factor receptors.

    Stephen G. Ball;C. Adrian Shuttleworth;Cay M. Kielty

Frequent Co-Authors

Carolyn J.P. Jones
Carolyn J.P. Jones University of Manchester
Michael Raghunath
Michael Raghunath Zurich University of Applied Sciences
Paul N. Bishop
Paul N. Bishop University of Manchester
Christopher E.M. Griffiths
Christopher E.M. Griffiths University of Manchester
Anthony S. Weiss
Anthony S. Weiss University of Sydney
Seth L. Schor
Seth L. Schor University of Dundee
Martin J. Humphries
Martin J. Humphries University of Manchester
Michael E. Grant
Michael E. Grant Wellcome Centre for Cell-Matrix Research
Ray Boot-Handford
Ray Boot-Handford University of Manchester
Linda D. Siracusa
Linda D. Siracusa Thomas Jefferson University

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