What is he best known for?
The fields of study he is best known for:
The scientist’s investigation covers issues in Cell biology, Extracellular matrix, Cartilage, Pathology and Molecular biology.
The various areas that he examines in his Cell biology study include Genetics, Cellular differentiation, Tissue homeostasis and Circadian clock, Circadian rhythm.
Ray Boot-Handford has included themes like Vertebrate, Genome, Anatomy and Unfolded protein response, Endoplasmic reticulum in his Extracellular matrix study.
As a part of the same scientific family, he mostly works in the field of Cartilage, focusing on Gene expression and, on occasion, Regulation of gene expression.
In general Pathology, his work in Calcification is often linked to Matrix gla protein and Cartilage oligomeric matrix protein linking many areas of study.
His work deals with themes such as Coding region, Complementary DNA, Blot, Untranslated region and Signal peptide, which intersect with Molecular biology.
His most cited work include:
- Collagens at a glance (512 citations)
- Setting clock speed in mammals: the CK1 epsilon tau mutation in mice accelerates circadian pacemakers by selectively destabilizing PERIOD proteins. (291 citations)
- Irf6 is a key determinant of the keratinocyte proliferation-differentiation switch (234 citations)
What are the main themes of his work throughout his whole career to date?
His main research concerns Cell biology, Biochemistry, Molecular biology, Gene and Cartilage.
His study in Cell biology is interdisciplinary in nature, drawing from both Chondrocyte, Circadian clock and Endochondral ossification.
His Molecular biology research includes themes of Epidermal growth factor, Protein subunit, Cysteine and Peptide sequence.
His Cartilage research is multidisciplinary, incorporating perspectives in Gene expression and Pathology.
His work focuses on many connections between Unfolded protein response and other disciplines, such as Mutant, that overlap with his field of interest in Mutation.
His Extracellular matrix research is multidisciplinary, relying on both Vertebrate and Anatomy.
He most often published in these fields:
- Cell biology (31.51%)
- Biochemistry (29.41%)
- Molecular biology (24.37%)
What were the highlights of his more recent work (between 2010-2021)?
- Cell biology (31.51%)
- Unfolded protein response (10.92%)
- Cartilage (16.39%)
In recent papers he was focusing on the following fields of study:
Ray Boot-Handford focuses on Cell biology, Unfolded protein response, Cartilage, Chondrocyte and Mutant.
His work on Signal transduction as part of general Cell biology research is frequently linked to Pseudoachondroplasia, bridging the gap between disciplines.
His biological study spans a wide range of topics, including Dwarfism, Mutant protein, Intracellular and Downregulation and upregulation.
His Cartilage study incorporates themes from Neuroscience, Circadian rhythm, Gene expression and Pathology.
His studies deal with areas such as Endocrinology, Immunology, Internal medicine, Pathogenic factor and Endochondral ossification as well as Chondrocyte.
His work in Mutant addresses subjects such as Molecular biology, which are connected to disciplines such as Extracellular matrix.
Between 2010 and 2021, his most popular works were:
- The expression and function of microRNAs in chondrogenesis and osteoarthritis. (169 citations)
- The chondrocyte clock gene Bmal1 controls cartilage homeostasis and integrity (89 citations)
- The Circadian Clock in Murine Chondrocytes Regulates Genes Controlling Key Aspects of Cartilage Homeostasis (85 citations)
In his most recent research, the most cited papers focused on:
His main research concerns Cartilage, Mutant, Cell biology, CLOCK and Circadian clock.
He interconnects Unfolded protein response and Molecular biology in the investigation of issues within Mutant.
His research is interdisciplinary, bridging the disciplines of Amino acid and Molecular biology.
The study incorporates disciplines such as Pathology and PER2 in addition to Cell biology.
His Circadian rhythm research is multidisciplinary, incorporating elements of Chondrocyte and Bioinformatics.
In his study, Wild type is strongly linked to Gene expression, which falls under the umbrella field of Chondrocyte.
This overview was generated by a machine learning system which analysed the scientist’s
body of work. If you have any feedback, you can
contact us
here.
