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D-Index & Metrics

Biology and Biochemistry

D-Index
79
Citations
17303
World Ranking
4410
National Ranking
331

Overview

Timothy E. Hardingham is affiliated with the Wellcome Centre for Cell-Matrix Research in the United Kingdom. Their research spans multiple fields, mainly focusing on Biochemistry, Genetics and Molecular Biology, Chemistry, and Medicine. Within these broad disciplines, they explore subfields including Molecular Biology, Organic Chemistry, and Radiology, Nuclear Medicine and Imaging.

Their work addresses several key research topics, with particular emphasis on Glycosylation and Glycoproteins Research, Carbohydrate Chemistry and Synthesis, and Monoclonal and Polyclonal Antibodies Research.

Timothy E. Hardingham has contributed to scholarly literature through publications, including at least one known paper titled "Assembly of the Respiratory Mucin MUC5B: A NEW MODEL FOR A GEL-FORMING MUCIN," published in 2020 in UNC Libraries. This paper has received citations in academic contexts.

Collaboration has been a component of their research activity, with several frequent co-authors noted. These include:

  • Caroline E. Ridley
  • Nikolaos Kouvatsos
  • Bertrand Raynal
  • Marj Howard
  • Richard F. Collins

Publications have appeared primarily in the venue UNC Libraries. There are no book publications recorded for this scientist.

Best Publications

  • Proteoglycans: many forms and many functions.

    Timothy E. Hardingham;Amanda J. Fosang

  • The specific interaction of hyaluronic acid with cartilage proteoglycans

    T.E. Hardingham;Helen Muir

  • The role of link-protein in the structure of cartilage proteoglycan aggregates

    T E Hardingham

  • Hyaluronic acid in cartilage and proteoglycan aggregation

    Timothy E. Hardingham;Helen Muir

  • The interglobular domain of cartilage aggrecan is cleaved by PUMP, gelatinases, and cathepsin B.

    Amanda J Fosang;Peter J Neame;Tim E Hardingham

  • Directed differentiation of human embryonic stem cells toward chondrocytes

    Rachel A Oldershaw;Melissa A Baxter;Emma T Lowe;Emma T Lowe;Nicola Bates

  • Proteoglycans of articular cartilage: Changes in aging and in joint disease

    Tim Hardingham;Michael Bayliss

  • Chondrogenic Differentiation of Human Bone Marrow Stem Cells in Transwell Cultures: Generation of Scaffold-Free Cartilage

    Alan D. Murdoch;Lisa M. Grady;Matthew P. Ablett;Theoni Katopodi

  • Modulation of native chondroitin sulphate structure in tissue development and in disease.

    B. Caterson;F. Mahmoodian;J.M. Sorrell;T.E. Hardingham

  • Biosynthesis of proteoglycans and their assembly into aggregates in cultures of chondrocytes from the Swarm rat chondrosarcoma.

    J H Kimura;T E Hardingham;V C Hascall;M Solursh

  • Cartilage proteoglycans. Structure and heterogeneity of the protein core and the effects of specific protein modifications on the binding to hyaluronate.

    T E Hardingham;R J F Ewins;H Muir

  • Hypoxic conditions increase hypoxia-inducible transcription factor 2α and enhance chondrogenesis in stem cells from the infrapatellar fat pad of osteoarthritis patients

    Wasim S Khan;Adetola B Adesida;Timothy E Hardingham

  • Tissue engineering: chondrocytes and cartilage

    Tim Hardingham;Simon Tew;Alan Murdoch

  • Binding of oligosaccharides of hyaluronic acid to proteoglycans (Short Communication)

    Timothy E. Hardingham;Helen Muir

  • Cleavage of cartilage proteoglycan between G1 and G2 domains by stromelysins.

    A J Fosang;P J Neame;T E Hardingham;G Murphy

  • Retroviral transduction with SOX9 enhances re-expression of the chondrocyte phenotype in passaged osteoarthritic human articular chondrocytes

    Simon R. Tew;Ying Li;Peraphan Pothacharoen;Lisa M. Tweats

  • Proteoglycans: their structure, interactions and molecular organization in cartilage.

    Tim Hardingham

  • Fibroblast and neutrophil collagenases cleave at two sites in the cartilage aggrecan interglobular domain.

    A J Fosang;V Knäuper;P J Neame

  • Extended and globular protein domains in cartilage proteoglycans.

    M Paulsson;M Mörgelin;H Wiedemann;M Beardmore-Gray

  • Cartilage proteoglycans. Assembly with hyaluronate and link protein as studied by electron microscopy

    M Mörgelin;M Paulsson;T E Hardingham;D Heinegård

Frequent Co-Authors

Amanda J. Fosang
Amanda J. Fosang Royal Children's Hospital
Anthony Ratcliffe
Anthony Ratcliffe Columbia University
Ray Boot-Handford
Ray Boot-Handford University of Manchester
Susan J. Kimber
Susan J. Kimber University of Manchester
Michael T. Bayliss
Michael T. Bayliss Royal Veterinary College
Robert E. Hawkins
Robert E. Hawkins University of Manchester
Peter D. Clegg
Peter D. Clegg University of Liverpool
Boon Chin Heng
Boon Chin Heng Peking University
David J. Thornton
David J. Thornton Wellcome Centre for Cell-Matrix Research
Bruce Caterson
Bruce Caterson Cardiff University

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