World's Best Scientists 2026 revealed!

D-Index & Metrics

Biology and Biochemistry

D-Index
70
Citations
18670
World Ranking
6967
National Ranking
166

Overview

Gianluigi Giannelli is affiliated with the Gastroenterology Hospital "Saverio de Bellis" in Italy. Their research primarily centers on the fields of Medicine and Biochemistry, Genetics and Molecular Biology. Within these areas, they have contributed extensively to subfields such as Molecular Biology, Epidemiology, Physiology, Hepatology, and Public Health, Environmental and Occupational Health.

The scientist's work addresses key topics including Liver Disease Diagnosis and Treatment, Diet and Metabolism Studies, Nutritional Studies and Diet, Diet, Metabolism, and Disease, Cholangiocarcinoma and Gallbladder Cancer Studies, MicroRNA in Disease Regulation, and Hepatocellular Carcinoma Treatment and Prognosis.

Giannelli's recent notable publications include the following:

  • Oral frailty and its determinants in older age: a systematic review (2021), published in The Lancet Healthy Longevity
  • Preliminary Trajectories in Dietary Behaviors during the COVID-19 Pandemic: A Public Health Call to Action to Face Obesity (2020), published in International Journal of Environmental Research and Public Health
  • Organs-on-chips technologies - A guide from disease models to opportunities for drug development (2023), published in Biosensors and Bioelectronics
  • Development of disease-modifying drugs for frontotemporal dementia spectrum disorders (2020), published in Nature Reviews Neurology
  • Epithelial-Mesenchymal Transition (EMT) Induced by TGF-β in Hepatocellular Carcinoma Cells Reprograms Lipid Metabolism (2021), published in International Journal of Molecular Sciences

Their frequent coauthors include:

  • Giovanni De Pergola
  • Rossella Donghia
  • Rodolfo Sardone
  • Roberta Zupo
  • Fabio Castellana

Giannelli has published numerous articles in journals such as:

  • Nutrients
  • International Journal of Molecular Sciences
  • Cancers
  • Journal of Experimental & Clinical Cancer Research
  • Biomedicines

Best Publications

  • Induction of cell migration by matrix metalloprotease-2 cleavage of laminin-5.

    Gianluigi Giannelli;Jutta Falk-Marzillier;Oronzo Schiraldi;William G. Stetler-Stevenson

  • Role of Cell Surface Metalloprotease Mt1-Mmp in Epithelial Cell Migration over Laminin-5

    Naohiko Koshikawa;Naohiko Koshikawa;Gianluigi Giannelli;Vincenzo Cirulli;Kaoru Miyazaki

  • TGF-β signalling and liver disease.

    Isabel Fabregat;Joaquim Moreno‐Càceres;Aránzazu Sánchez;Steven Dooley

  • Role of epithelial to mesenchymal transition in hepatocellular carcinoma

    Gianluigi Giannelli;Petra Koudelkova;Francesco Dituri;Wolfgang Mikulits

  • Dietary fiber and health outcomes: an umbrella review of systematic reviews and meta-analyses.

    Nicola Veronese;Marco Solmi;Maria Gabriella Caruso;Gianluigi Giannelli

  • Laminin-5 With Transforming Growth Factor-β1 Induces Epithelial to Mesenchymal Transition in Hepatocellular Carcinoma

    G. Giannelli;C. Bergamini;E. Fransvea;C. Sgarra

  • Different Cognitive Frailty Models and Health- and Cognitive-related Outcomes in Older Age: From Epidemiology to Prevention.

    Francesco Panza;Francesco Panza;Madia Lozupone;Vincenzo Solfrizzi;Rodolfo Sardone

  • Blocking transforming growth factor-beta up-regulates E-cadherin and reduces migration and invasion of hepatocellular carcinoma cells.

    Emilia Fransvea;Umberto Angelotti;Salvatore Antonaci;Gianluigi Giannelli

  • TGF-β and the Tissue Microenvironment: Relevance in Fibrosis and Cancer.

    Laia Caja;Francesco Dituri;Serena Mancarella;Daniel Caballero-Diaz

  • Transforming Growth Factor-β as a Therapeutic Target in Hepatocellular Carcinoma

    Gianluigi Giannelli;Erica Villa;Michael Lahn

  • Clinical role of MMP-2/TIMP-2 imbalance in hepatocellular carcinoma.

    Gianluigi Giannelli;Carlo Bergamini;Felice Marinosci;Emilia Fransvea

  • Neoangiogenesis-related genes are hallmarks of fast-growing hepatocellular carcinomas and worst survival. Results from a prospective study

    Erica Villa;Rosina Critelli;Barbara Lei;Guido Marzocchi

  • Drug-loaded polyelectrolyte microcapsules for sustained targeting of cancer cells.

    Viviana Vergaro;Flavia Scarlino;Claudia Bellomo;Rosaria Rinaldi

  • Transforming Growth Factor-β1 Triggers Hepatocellular Carcinoma Invasiveness via α3β1 Integrin

    Gianluigi Giannelli;Emilia Fransvea;Felice Marinosci;Carlo Bergamini

  • Down‐regulation of connective tissue growth factor by inhibition of transforming growth factor β blocks the tumor–stroma cross‐talk and tumor progression in hepatocellular carcinoma

    Antonio Mazzocca;Emilia Fransvea;Francesco Dituri;Luigi Lupo

  • A Phase 2 Study of Galunisertib (TGF-β1 Receptor Type I Inhibitor) and Sorafenib in Patients With Advanced Hepatocellular Carcinoma.

    R.K. Kelley;E. Gane;E. Assenat;J. Siebler

  • Oral frailty and its determinants in older age: a systematic review

    Vittorio Dibello;Roberta Zupo;Rodolfo Sardone;Madia Lozupone

  • Human hepatocellular carcinoma (HCC) cells require both alpha3beta1 integrin and matrix metalloproteinases activity for migration and invasion.

    Gianluigi Giannelli;Carlo Bergamini;Emilia Fransvea;Felice Marinosci

  • Targeting transforming growth factor (TGF)‐βRI inhibits activation of β1 integrin and blocks vascular invasion in hepatocellular carcinoma

    Emilia Fransvea;Antonio Mazzocca;Antonio Mazzocca;Salvatore Antonaci;Gianluigi Giannelli

  • AFP, PIVKAII, GP3, SCCA-1 and follisatin as surveillance biomarkers for hepatocellular cancer in non-alcoholic and alcoholic fatty liver disease

    Gary Beale;Dipankar Chattopadhyay;Joe Gray;Stephen Stewart

Frequent Co-Authors

Francesco Panza
Francesco Panza University of Bari Aldo Moro
Isabel Fabregat
Isabel Fabregat University of Barcelona
Guido Antonelli
Guido Antonelli Sapienza University of Rome
Giancarlo Logroscino
Giancarlo Logroscino University of Bari Aldo Moro
Vito Quaranta
Vito Quaranta Vanderbilt University
Angelo Paradiso
Angelo Paradiso National Cancer Research Institute, UK
Vincenzo Solfrizzi
Vincenzo Solfrizzi University of Bari Aldo Moro
Edward Gane
Edward Gane Auckland City Hospital
Heiner Boeing
Heiner Boeing German Institute of Human Nutrition
Nicola Veronese
Nicola Veronese University of Palermo

If you think any of the details on this page are incorrect, let us know.

Report an issue

We appreciate your kind effort to assist us to improve this page, it would be helpful providing us with as much detail as possible in the text box below:

Related Online Degrees & Career Pathways

Studying Biology and Biochemistry in the USA opens doors to a variety of online degrees and rewarding career pathways in healthcare, research, and wellness. Many professionals are accelerating their careers by pursuing specialized online education that builds on their scientific backgrounds.

For those with a nursing foundation, seamless transitions are possible through programs like the rn to bsn online, helping students move from registered nurse to bachelor’s qualification with flexible study. If you’re interested in leadership roles within healthcare systems, the fastest online mha programs can help you fast-track your management ambitions.

Those drawn to mental health may consider fast track mental health nursing options, allowing individuals to specialize quickly in psychiatric and mental health roles. Alternatively, a passion for nutrition can be realized through nutrition degree programs, which prepare graduates for dynamic work in dietetics, wellness, and health promotion.

Exploring these related online degrees can expand your professional scope, providing versatile pathways for biology and biochemistry graduates to succeed across a range of fast-growing sectors.

Best Scientists Citing Gianluigi Giannelli

Trending Scientists

Recently Published Articles