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D-Index & Metrics

Biology and Biochemistry

D-Index
56
Citations
10858
World Ranking
14466
National Ranking
130

Overview

Wolfgang Mikulits is affiliated with the Medical University of Vienna in Austria and has contributed extensively to the fields of Medicine and Immunology and Microbiology. Their research encompasses several focused subfields, including Immunology, Oncology, Hepatology, Surgery, and Molecular Biology.

Their work predominantly covers topics such as Phagocytosis and Immune Regulation, Pancreatic and Hepatic Oncology Research, Liver Physiology and Pathology, Cancer Research and Treatments, Pancreatitis Pathology and Treatment, Virus-based Gene Therapy Research, and RNA Interference and Gene Delivery.

Mikulits has published in a variety of scientific venues, frequently contributing to the following journals:

  • Journal of Hepatology
  • Clinical Cancer Research
  • Cells
  • Cancers
  • bioRxiv (Cold Spring Harbor Laboratory)

Recent papers authored or co-authored by Mikulits include:

  • α2-Adrenergic Receptor in Liver Fibrosis: Implications for the Adrenoblocker Mesedin, 2020, Cells
  • PRAME Is a Novel Target of Tumor-Intrinsic Gas6/Axl Activation and Promotes Cancer Cell Invasion in Hepatocellular Carcinoma, 2023, Cancers
  • Intrinsic and Extrinsic Control of Hepatocellular Carcinoma by TAM Receptors, 2021, Cancers
  • Antifibrotic Effects of Amyloid-Beta and Its Loss in Cirrhotic Liver, 2020, Cells
  • Immunological Aspects of AXL/GAS-6 in the Context of Human Liver Regeneration, 2021, Hepatology Communications

Frequent collaborators in their research include:

  • Gregor Ortmayr
  • Patrick Starlinger
  • Gerhard Weber
  • Viola Hedrich
  • Kristina Breitenecker

Mikulits's scientific contributions largely revolve around liver-related pathologies and cancer research, with a significant emphasis on immunological mechanisms and molecular pathways involved in hepatocellular carcinoma and liver fibrosis. Their research also explores receptor signaling pathways, tumor cell invasion, and immune regulatory processes in tissue regeneration and cancer progression.

Best Publications

  • Initial steps of metastasis: Cell invasion and endothelial transmigration

    Franziska van Zijl;Georg Krupitza;Wolfgang Mikulits

  • The transcription factor ZEB1 (δEF1) promotes tumour cell dedifferentiation by repressing master regulators of epithelial polarity

    K Aigner;B Dampier;L Descovich;M Mikula

  • Role of epithelial to mesenchymal transition in hepatocellular carcinoma

    Gianluigi Giannelli;Petra Koudelkova;Francesco Dituri;Wolfgang Mikulits

  • Epithelial–mesenchymal transition in hepatocellular carcinoma

    Franziska van Zijl;Gudrun Zulehner;Michaela Petz;Doris Schneller

  • Molecular aspects of epithelial cell plasticity: implications for local tumor invasion and metastasis.

    Josef Gotzmann;Mario Mikula;Andreas Eger;Rolf Schulte-Hermann

  • La enhances IRES-mediated translation of Laminin B1 during malignant epithelial to mesenchymal transition.

    Michaela Petz;Nicole C. C. Them;Heidemarie Huber;Hartmut Beug

  • A crucial function of PDGF in TGF-beta-mediated cancer progression of hepatocytes.

    J Gotzmann;A N M Fischer;M Zojer;M Mikula

  • Hepatocytes convert to a fibroblastoid phenotype through the cooperation of TGF-β1 and Ha-Ras: steps towards invasiveness

    Josef Gotzmann;Heidemarie Huber;Christiane Thallinger;Markus Wolschek

  • Hepatic tumor-stroma crosstalk guides epithelial to mesenchymal transition at the tumor edge.

    F van Zijl;M Mair;A Csiszar;D Schneller

  • Lipoxygenase mediates invasion of intrametastatic lymphatic vessels and propagates lymph node metastasis of human mammary carcinoma xenografts in mouse

    Dontscho Kerjaschki;Zsuzsanna Bago-Horvath;Margaretha Rudas;Veronika Sexl;Veronika Sexl

  • beta-Catenin and TGFbeta signalling cooperate to maintain a mesenchymal phenotype after FosER-induced epithelial to mesenchymal transition.

    Andreas Eger;Andreas Stockinger;John Park;Elke Langkopf

  • Meta-analysis of gene expression signatures defining the epithelial to mesenchymal transition during cancer progression.

    Christian J. Gröger;Markus Grubinger;Thomas Waldhör;Klemens Vierlinger

  • PDGF essentially links TGF- β signaling to nuclear β -catenin accumulation in hepatocellular carcinoma progression

    A. N M Fischer;E. Fuchs;M. Mikula;H. Huber

  • Axl activates autocrine transforming growth factor‐β signaling in hepatocellular carcinoma

    Patrick Reichl;Mirko Dengler;Franziska van Zijl;Heidemarie Huber

  • STAT3 regulated ARF expression suppresses prostate cancer metastasis

    Jan Pencik;Michaela Schlederer;Wolfgang Gruber;Christine Unger

  • NADPH Oxidase NOX4 Mediates Stellate Cell Activation and Hepatocyte Cell Death during Liver Fibrosis Development

    Patricia Sancho;Jèssica Mainez;Eva Crosas-Molist;César Roncero

  • Use of conventional and -omics based methods for health claims of dietary antioxidants: a critical overview

    Siegfried Knasmüller;Armen Nersesyan;Miroslav Mišík;Christopher Gerner

  • Down-regulation of Sprouty2 in non-small cell lung cancer contributes to tumor malignancy via extracellular signal-regulated kinase pathway-dependent and -independent mechanisms.

    Hedwig Sutterlüty;Christoph-Erik Mayer;Ulrike Setinek;Johannes Attems

  • Activated hepatic stellate cells induce tumor progression of neoplastic hepatocytes in a TGF-β dependent fashion

    M. Mikula;V. Proell;A.N.M. Fischer;W. Mikulits

  • Laminin-332 sustains chemoresistance and quiescence as part of the human hepatic cancer stem cell niche.

    Olivier Govaere;Jasper Wouters;Michaela Petz;Yves-Paul Vandewynckel

Frequent Co-Authors

Hartmut Beug
Hartmut Beug Research Institute of Molecular Pathology
Isabel Fabregat
Isabel Fabregat University of Barcelona
Richard Moriggl
Richard Moriggl University of Veterinary Medicine Vienna
Walter Berger
Walter Berger Medical University of Vienna
Harald Esterbauer
Harald Esterbauer Medical University of Vienna
Michael Trauner
Michael Trauner Medical University of Vienna
Gianluigi Giannelli
Gianluigi Giannelli Gastroenterology Hospital "Saverio de Bellis"
Aristidis Moustakas
Aristidis Moustakas Uppsala University
Siegfried Knasmüller
Siegfried Knasmüller Medical University of Vienna
Markus Peck-Radosavljevic
Markus Peck-Radosavljevic Klinikum Klagenfurt

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