D-Index & Metrics Best Publications
Biology and Biochemistry
Canada
2023

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Medicine D-index 83 Citations 22,115 176 World Ranking 10586 National Ranking 407
Biology and Biochemistry D-index 86 Citations 22,765 180 World Ranking 1942 National Ranking 50

Research.com Recognitions

Awards & Achievements

2023 - Research.com Biology and Biochemistry in Canada Leader Award

2020 - Fellow of the Royal Society of Canada Academy of Science

2014 - Robert L. Noble Prize, Canadian Cancer Society

Overview

What is he best known for?

The fields of study he is best known for:

  • Gene
  • Cancer
  • Enzyme

Internal medicine, Endocrinology, Matrix metalloproteinase, Extracellular matrix and Metastasis are his primary areas of study. He has researched Internal medicine in several fields, including Apoptosis and Programmed cell death. The Endocrinology study combines topics in areas such as Receptor, Cell cycle and Stem cell.

His Extracellular matrix research is classified as research in Cell biology. His Metastasis research is multidisciplinary, incorporating elements of Cancer cell, Melanoma, Immunology and Pathology. His Cancer cell research incorporates elements of Cancer research and Extravasation.

His most cited work include:

  • The osteoclast differentiation factor osteoprotegerin-ligand is essential for mammary gland development. (621 citations)
  • Regulation of cancer cell migration and bone metastasis by RANKL (605 citations)
  • Progesterone induces adult mammary stem cell expansion (518 citations)

What are the main themes of his work throughout his whole career to date?

Rama Khokha spends much of his time researching Cancer research, Matrix metalloproteinase, Cell biology, Immunology and Internal medicine. His Cancer research research integrates issues from Carcinogenesis, Cancer, Breast cancer, Mammary gland and Phenotype. The concepts of his Matrix metalloproteinase study are interwoven with issues in Extracellular matrix, Genetically modified mouse, Metastasis and Pathology.

The study incorporates disciplines such as Cellular differentiation, Cell growth and Metalloproteinase in addition to Cell biology. His research investigates the connection between Immunology and topics such as Cell culture that intersect with problems in Molecular biology. As part of one scientific family, Rama Khokha deals mainly with the area of Internal medicine, narrowing it down to issues related to the Endocrinology, and often Inflammation.

He most often published in these fields:

  • Cancer research (39.58%)
  • Matrix metalloproteinase (30.21%)
  • Cell biology (31.77%)

What were the highlights of his more recent work (between 2016-2021)?

  • Cancer research (39.58%)
  • Progenitor cell (16.67%)
  • Cell biology (31.77%)

In recent papers he was focusing on the following fields of study:

Rama Khokha focuses on Cancer research, Progenitor cell, Cell biology, Stem cell and Breast cancer. His research in Cancer research intersects with topics in Cancer, Metastasis, Pancreatic cancer, Phenotype and Notch signaling pathway. His work focuses on many connections between Progenitor cell and other disciplines, such as Cell, that overlap with his field of interest in Mammary gland and Proteomics.

Rama Khokha combines subjects such as Stromal cell, Matrix metalloproteinase, Long bone and Fibroblast growth factor with his study of Cell biology. His Stem cell study frequently draws connections between adjacent fields such as Immunology. His study in the fields of Bone marrow under the domain of Immunology overlaps with other disciplines such as Ecological niche.

Between 2016 and 2021, his most popular works were:

  • TIMPs: versatile extracellular regulators in cancer (163 citations)
  • Metalloproteinases in extracellular vesicles (52 citations)
  • MiR-26a inhibits stem cell-like phenotype and tumor growth of osteosarcoma by targeting Jagged1. (47 citations)

In his most recent research, the most cited papers focused on:

  • Gene
  • Cancer
  • Enzyme

Rama Khokha mainly investigates Stem cell, Progenitor cell, Cell biology, Population and Cellular differentiation. The study of Stem cell is intertwined with the study of Cancer research in a number of ways. He focuses mostly in the field of Cancer research, narrowing it down to matters related to Notch signaling pathway and, in some cases, Osteosarcoma.

His Progenitor cell study combines topics from a wide range of disciplines, such as Cell, Epigenomics, DNA methylation and Proteomics. His work on Extracellular matrix as part of general Cell biology research is frequently linked to Context, thereby connecting diverse disciplines of science. His studies deal with areas such as Cell migration, Stromal cell, Morphogenesis and Mesenchymal stem cell as well as Cellular differentiation.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

Regulation of cancer cell migration and bone metastasis by RANKL

D. Holstead Jones;Tomoki Nakashima;Otto H. Sanchez;Otto H. Sanchez;Ivona Kozieradzki;Ivona Kozieradzki.
Nature (2006)

908 Citations

The osteoclast differentiation factor osteoprotegerin-ligand is essential for mammary gland development

Jimmie E Fata;Young-Yun Kong;Young-Yun Kong;Ji Li;Takehiko Sasaki.
Cell (2000)

876 Citations

Progesterone induces adult mammary stem cell expansion

Purna A. Joshi;Hartland W. Jackson;Alexander G. Beristain;Marco A. Di Grappa.
Nature (2010)

713 Citations

Glutathione and Thioredoxin Antioxidant Pathways Synergize to Drive Cancer Initiation and Progression

Isaac S. Harris;Aislinn E. Treloar;Satoshi Inoue;Masato Sasaki.
Cancer Cell (2015)

710 Citations

Tissue inhibitor of metalloproteinases-3 (TIMP-3) is an extracellular matrix-associated protein with a distinctive pattern of expression in mouse cells and tissues.

K J Leco;R Khokha;N Pavloff;S P Hawkes.
Journal of Biological Chemistry (1994)

607 Citations

Suppression of tumor growth and metastasis in Mgat5-deficient mice.

Maria Granovsky;Maria Granovsky;Jimmie Fata;Judy Pawling;William J. Muller.
Nature Medicine (2000)

604 Citations

Antisense RNA-induced reduction in murine TIMP levels confers oncogenicity on Swiss 3T3 cells.

Rama Khokha;Paul Waterhouse;Simcha Yagel;Peeyush K. Lala.
Science (1989)

591 Citations

Osteoclast differentiation factor RANKL controls development of progestin-driven mammary cancer.

Daniel Schramek;Andreas Leibbrandt;Verena Sigl;Lukas Kenner.
Nature (2010)

583 Citations

Metalloproteinases and their natural inhibitors in inflammation and immunity

Rama Khokha;Aditya Murthy;Ashley Weiss.
Nature Reviews Immunology (2013)

530 Citations

Tumor Necrosis Factor-α Mediates Cardiac Remodeling and Ventricular Dysfunction After Pressure Overload State

Mei Sun;Manyin Chen;Fayez Dawood;Urszula Zurawska.
Circulation (2007)

422 Citations

If you think any of the details on this page are incorrect, let us know.

Contact us

Best Scientists Citing Rama Khokha

Josef M. Penninger

Josef M. Penninger

University of British Columbia

Publications: 97

Gavin Y. Oudit

Gavin Y. Oudit

University of Alberta

Publications: 68

James W. Dennis

James W. Dennis

Lunenfeld-Tanenbaum Research Institute

Publications: 66

Ann F. Chambers

Ann F. Chambers

University of Western Ontario

Publications: 62

Carl P. Blobel

Carl P. Blobel

Cornell University

Publications: 57

Naoyuki Taniguchi

Naoyuki Taniguchi

Osaka University

Publications: 55

Dominique Heymann

Dominique Heymann

University of Nantes

Publications: 51

Gillian Murphy

Gillian Murphy

University of Cambridge

Publications: 49

Dylan R. Edwards

Dylan R. Edwards

University of East Anglia

Publications: 47

Zena Werb

Zena Werb

University of California, San Francisco

Publications: 46

William G. Stetler-Stevenson

William G. Stetler-Stevenson

National Institutes of Health

Publications: 44

Hideaki Nagase

Hideaki Nagase

University of Oxford

Publications: 41

Tak W. Mak

Tak W. Mak

Princess Margaret Cancer Centre

Publications: 38

Stefan Rose-John

Stefan Rose-John

Kiel University

Publications: 34

Geoffrey J. Lindeman

Geoffrey J. Lindeman

Walter and Eliza Hall Institute of Medical Research

Publications: 32

Eiji Miyoshi

Eiji Miyoshi

Osaka University

Publications: 31

Trending Scientists

John A. Miller

John A. Miller

University of Georgia

Shoji Makino

Shoji Makino

Waseda University

Andreas Gansäuer

Andreas Gansäuer

University of Bonn

Ana Soto

Ana Soto

University of Santiago de Compostela

Min Cho

Min Cho

Jeonbuk National University

Miquel Coll

Miquel Coll

Spanish National Research Council

Michael Solursh

Michael Solursh

University of Iowa

Andrew J. Easton

Andrew J. Easton

University of Warwick

Pascal Allemand

Pascal Allemand

École Normale Supérieure de Lyon

T. A. Black

T. A. Black

University of British Columbia

Janet R. Keast

Janet R. Keast

University of Melbourne

Oskar Hansson

Oskar Hansson

Lund University

Howard A. Bern

Howard A. Bern

University of California, Berkeley

Claudio Ronco

Claudio Ronco

University of Padua

Erik Fink Eriksen

Erik Fink Eriksen

University of Oslo

Karsten Hank

Karsten Hank

University of Cologne

Something went wrong. Please try again later.