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Medicine

D-Index
80
Citations
33624
World Ranking
16916
National Ranking
567

Research.com Recognitions

  • 2016 - Fellow of the Australian Academy of Science
  • 2015 - Fellow of the Australian Academy of Health and Medical Science

Overview

Geoffrey J. Lindeman is affiliated with the Peter MacCallum Cancer Centre in Australia, focusing on research primarily within the fields of Medicine and Biochemistry, Genetics and Molecular Biology. Their scientific contributions emphasize oncology, molecular biology, genetics, cancer research, and pulmonary and respiratory medicine.

Their research extensively covers several main topics including cancer genomics and diagnostics, BRCA gene mutations in cancer, advanced breast cancer therapies, cancer cells and metastasis, chronic lymphocytic leukemia research, single-cell and spatial transcriptomics, and cancer-related molecular pathways.

Geoffrey J. Lindeman has contributed to numerous peer-reviewed publications in various academic journals. Frequent publication venues are Cancer Research, Journal of Clinical Oncology, Clinical Cancer Research, Nature Communications, and The Medical Journal of Australia.

  • Deciphering breast cancer: from biology to the clinic (2023, Cell)
  • A single-cell RNA expression atlas of normal, preneoplastic and tumorigenic states in the human breast (2021, The EMBO Journal)
  • Tissue-resident ductal macrophages survey the mammary epithelium and facilitate tissue remodelling (2020, Nature Cell Biology)
  • Dual Targeting of CDK4/6 and BCL2 Pathways Augments Tumor Response in Estrogen Receptor-Positive Breast Cancer (2020, Clinical Cancer Research)
  • Mammary tumour cells remodel the bone marrow vascular microenvironment to support metastasis (2021, Nature Communications)

Collaborations have been frequent with several co-authors, including Jane E. Visvader, François Vaillant, Gordon K. Smyth, Paul A. James, and Yunshun Chen.

Lindeman has been recognized by election as a Fellow of the Australian Academy of Science in 2016 and as a Fellow of the Australian Academy of Health and Medical Science in 2015.

Best Publications

  • Cancer stem cells in solid tumours: accumulating evidence and unresolved questions

    Jane E. Visvader;Geoffrey J. Lindeman;Geoffrey J. Lindeman

  • Generation of a functional mammary gland from a single stem cell

    Mark Shackleton;Mark Shackleton;Francois Vaillant;Francois Vaillant;Kaylene J. Simpson;Kaylene J. Simpson;John Stingl

  • Cancer stem cells: current status and evolving complexities.

    Jane E. Visvader;Jane E. Visvader;Geoffrey J. Lindeman;Geoffrey J. Lindeman;Geoffrey J. Lindeman

  • Aberrant luminal progenitors as the candidate target population for basal tumor development in BRCA1 mutation carriers

    Elgene Lim;Elgene Lim;Francois Vaillant;Di Wu;Di Wu;Natasha C Forrest

  • Breast-Cancer Risk in Families with Mutations in PALB2

    A. C. Antoniou;S. Casadei;T. Heikkinen;D. Barrowdale

  • Gata-3 is an essential regulator of mammary-gland morphogenesis and luminal-cell differentiation

    Marie Liesse Asselin-Labat;Kate D. Sutherland;Kate D. Sutherland;Holly Barker;Holly Barker;Richard Thomas

  • Control of mammary stem cell function by steroid hormone signalling

    Marie Liesse Asselin-Labat;François Vaillant;Julie M. Sheridan;Bhupinder Pal

  • An autocrine TGF-β/ZEB/miR-200 signaling network regulates establishment and maintenance of epithelial-mesenchymal transition

    Philip A. Gregory;Cameron P. Bracken;Cameron P. Bracken;Eric Smith;Andrew G. Bert

  • Cyclin D1 transgene impedes lymphocyte maturation and collaborates in lymphomagenesis with the myc gene.

    S.E. Bodrug;B.J. Warner;M.L. Bath;G.J. Lindeman

  • In situ identification of bipotent stem cells in the mammary gland

    Anne C. Rios;Nai Yang Fu;Nai Yang Fu;Geoffrey J. Lindeman;Jane E. Visvader

  • Notch signaling regulates mammary stem cell function and luminal cell-fate commitment.

    Toula Bouras;Bhupinder Pal;François Vaillant;Gwyndolen Harburg

  • Transcriptome analyses of mouse and human mammary cell subpopulations reveal multiple conserved genes and pathways

    Elgene Lim;Elgene Lim;Di Wu;Di Wu;Bhupinder Pal;Toula Bouras

  • The Mammary Progenitor Marker CD61/β3 Integrin Identifies Cancer Stem Cells in Mouse Models of Mammary Tumorigenesis

    François Vaillant;Marie Liesse Asselin-Labat;Mark Shackleton;Mark Shackleton;Natasha C. Forrest

  • E2F4 and E2F5 play an essential role in pocket protein-mediated G1 control

    Stefan Gaubatz;Geoffrey J. Lindeman;Seiichi Ishida;Laszlo Jakoi

  • Steroid Hormone Receptor Status of Mouse Mammary Stem Cells

    Marie Liesse Asselin-Labat;Mark Shackleton;Mark Shackleton;John Stingl;François Vaillant

  • Patient-derived xenograft models of breast cancer and their predictive power

    James R Whittle;Michael T Lewis;Geoffrey J Lindeman;Geoffrey J Lindeman;Geoffrey J Lindeman;Jane E Visvader;Jane E Visvader

  • Targeting BCL-2 with the BH3 Mimetic ABT-199 in Estrogen Receptor-Positive Breast Cancer

    François Vaillant;Delphine Merino;Delphine Merino;Lily Lee;Lily Lee;Kelsey Breslin

  • The proapoptotic BH3-only protein bim is expressed in hematopoietic, epithelial, neuronal, and germ cells.

    Lorraine A. O’Reilly;Leonie Cullen;Jane Visvader;Jane Visvader;Geoffrey J. Lindeman;Geoffrey J. Lindeman

  • A single-cell RNA expression atlas of normal, preneoplastic and tumorigenic states in the human breast.

    Bhupinder Pal;Yunshun Chen;Yunshun Chen;François Vaillant;François Vaillant;Bianca D Capaldo;Bianca D Capaldo

  • Targeted Prostate Cancer Screening in BRCA1 and BRCA2 Mutation Carriers: Results from the Initial Screening Round of the IMPACT Study

    Elizabeth K. Bancroft;Elizabeth C. Page;Elena Castro;Hans Lilja

Frequent Co-Authors

Jane E. Visvader
Jane E. Visvader Walter and Eliza Hall Institute of Medical Research
François Vaillant
François Vaillant Walter and Eliza Hall Institute of Medical Research
Gordon K. Smyth
Gordon K. Smyth Walter and Eliza Hall Institute of Medical Research
Clare L. Scott
Clare L. Scott Walter and Eliza Hall Institute of Medical Research
Stephen B. Fox
Stephen B. Fox Peter MacCallum Cancer Centre
Ian G. Campbell
Ian G. Campbell Peter MacCallum Cancer Centre
John L. Hopper
John L. Hopper University of Melbourne
Susan M. Domchek
Susan M. Domchek University of Pennsylvania
Matthew E. Ritchie
Matthew E. Ritchie Walter and Eliza Hall Institute of Medical Research
Rosalind A. Eeles
Rosalind A. Eeles Institute of Cancer Research

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