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Molecular Biology

D-Index
49
Citations
9716
World Ranking
2626
National Ranking
63

Overview

Alexander Swarbrick is affiliated with the Garvan Institute of Medical Research in Australia. Their research primarily spans the fields of Biochemistry, Genetics and Molecular Biology, and Medicine, with a focus on molecular biology and oncology subfields.

The scientist's research interests cover a range of topics centered on cancer and immune system interactions. These include:

  • Single-cell and spatial transcriptomics
  • Cancer Cells and Metastasis
  • Cancer Genomics and Diagnostics
  • Cancer Immunotherapy and Biomarkers
  • Immune cells in cancer
  • Advanced Breast Cancer Therapies
  • Immunotherapy and Immune Responses

Swarbrick has contributed extensively to scientific literature, with notable recent publications including:

  • A single-cell and spatially resolved atlas of human breast cancers, 2021, Nature Genetics
  • Cross-tissue single-cell landscape of human monocytes and macrophages in health and disease, 2021, Immunity
  • Stromal cell diversity associated with immune evasion in human triple-negative breast cancer, 2020, The EMBO Journal
  • Spatial deconvolution of HER2-positive breast cancer delineates tumor-associated cell type interactions, 2021, Nature Communications
  • The androgen receptor is a tumor suppressor in estrogen receptor-positive breast cancer, 2021, Nature Medicine

The scientist frequently collaborates with a set of co-authors, including:

  • Kate Harvey
  • Ghamdan Al-Eryani
  • Sunny Z. Wu
  • Daniel Roden
  • Elgene Lim

In terms of publication venues, they have the most publications in:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Cancer Research
  • Nature Communications
  • Breast Cancer Research
  • Cancers

Best Publications

  • A single-cell and spatially resolved atlas of human breast cancers.

    Sunny Z. Wu;Sunny Z. Wu;Ghamdan Al-Eryani;Ghamdan Al-Eryani;Daniel Lee Roden;Daniel Lee Roden;Simon Junankar;Simon Junankar

  • Cross-tissue single-cell landscape of human monocytes and macrophages in health and disease.

    Kevin Mulder;Kevin Mulder;Kevin Mulder;Amit Ashok Patel;Amit Ashok Patel;Wan Ting Kong;Cécile Piot

  • Targeting stromal remodeling and cancer stem cell plasticity overcomes chemoresistance in triple negative breast cancer

    Aurélie S. Cazet;Aurélie S. Cazet;Mun N. Hui;Benjamin L. Elsworth;Sunny Z. Wu;Sunny Z. Wu

  • High-throughput targeted long-read single cell sequencing reveals the clonal and transcriptional landscape of lymphocytes

    Mandeep Singh;Mandeep Singh;Ghamdan Al-Eryani;Ghamdan Al-Eryani;Shaun Carswell;James M. Ferguson

  • Stromal cell diversity associated with immune evasion in human triple-negative breast cancer.

    Sunny Z. Wu;Sunny Z. Wu;Daniel L. Roden;Daniel L. Roden;Chenfei Wang;Holly Holliday;Holly Holliday

  • Spatial deconvolution of HER2-positive breast cancer delineates tumor-associated cell type interactions

    Alma Andersson;Ludvig Larsson;Linnea Stenbeck;Fredrik Salmén;Fredrik Salmén

  • Programmed death ligand 1 expression in triple-negative breast cancer is associated with tumour-infiltrating lymphocytes and improved outcome.

    Rhiannon K Beckers;Christina I Selinger;Ricardo Vilain;Ricardo Vilain;Jason Madore

  • miR-380-5p represses p53 to control cellular survival and is associated with poor outcome in MYCN-amplified neuroblastoma

    Alexander Swarbrick;Alexander Swarbrick;Susan L Woods;Susan L Woods;Alexander Shaw;Alexander Shaw;Alexander Shaw;Asha Balakrishnan

  • Tyrosine phosphorylation profiling reveals the signaling network characteristics of basal breast cancer cells

    Falko Hochgrafe;Luxi Zhang;Sandra A O'Toole;Brigid C Browne

  • Hedgehog Overexpression Is Associated with Stromal Interactions and Predicts for Poor Outcome in Breast Cancer

    Sandra A. O'Toole;Dorothy A. Machalek;Robert F. Shearer;Ewan K.A. Millar

  • The androgen receptor is a tumor suppressor in estrogen receptor–positive breast cancer

    Theresa E. Hickey;Luke A. Selth;Luke A. Selth;Kee Ming Chia;Geraldine Laven-Law

  • Therapeutic targets in triple negative breast cancer

    Sandra A O'Toole;Jane M Beith;Jane M Beith;Ewan K A Millar;Richard West;Richard West

  • Mechanisms of Cyclin-Dependent Kinase Inactivation by Progestins

    Elizabeth A. Musgrove;Alexander Swarbrick;Christine S. L. Lee;Ann L. Cornish

  • Real-time intravital imaging establishes tumor-associated macrophages as the extraskeletal target of bisphosphonate action in cancer.

    Simon Junankar;Gemma Shay;Julie Jurczyluk;Naveid Ali

  • Circulating microRNAs are associated with docetaxel chemotherapy outcome in castration-resistant prostate cancer.

    Hui-Ming Lin;Lesley Castillo;K L Mahon;K L Mahon;Karen HuiQin Chiam

  • MicroRNAs Regulate Tumor Angiogenesis Modulated by Endothelial Progenitor Cells

    Prue Neilson Plummer;Ruth Freeman;Ryan J. Taft;Jelena Vider

  • Id1 cooperates with oncogenic Ras to induce metastatic mammary carcinoma by subversion of the cellular senescence response

    Alexander Swarbrick;Emie Roy;Thaddeus Allen;J. Michael Bishop

  • A quantitative mass spectrometry-based approach to monitor the dynamics of endogenous chromatin-associated protein complexes.

    Evangelia Papachristou;Kamal Kishore;Andrew Nicholas Holding;Kate Harvey

  • The Hedgehog signalling pathway in breast development, carcinogenesis and cancer therapy.

    Mun Hui;Aurélie Cazet;Radhika Nair;D Neil Watkins

  • Effects of a Novel Long Noncoding RNA, lncUSMycN, on N-Myc Expression and Neuroblastoma Progression

    Pei Y. Liu;Daniela Erriquez;Glenn M. Marshall;Andrew E. Tee

Frequent Co-Authors

Elizabeth A. Musgrove
Elizabeth A. Musgrove University of Glasgow
Roger J. Daly
Roger J. Daly Monash University
Jason S. Carroll
Jason S. Carroll University of Cambridge
Robert L. Sutherland
Robert L. Sutherland Garvan Institute of Medical Research
Sunil R. Lakhani
Sunil R. Lakhani University of Queensland
Susan J. Clark
Susan J. Clark Garvan Institute of Medical Research
Paul Timpson
Paul Timpson Garvan Institute of Medical Research
Wayne D. Tilley
Wayne D. Tilley University of Adelaide
Joseph E. Powell
Joseph E. Powell Garvan Institute of Medical Research
Richard A. Scolyer
Richard A. Scolyer Royal Prince Alfred Hospital

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