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Genetics

D-Index
83
Citations
32147
World Ranking
1403
National Ranking
45

Overview

Susan J. Clark is affiliated with the Garvan Institute of Medical Research in Australia. Their research primarily focuses on the intersection of biochemistry, genetics, and molecular biology, with significant contributions to medicine. Within these broad fields, their subfield specializations include molecular biology, cancer research, pulmonary and respiratory medicine, genetics, and oncology.

The scientific work of Susan J. Clark prominently addresses topics such as epigenetics and DNA methylation, RNA modifications and cancer, genomics and chromatin dynamics, cancer-related gene regulation, prostate cancer treatment and research, cancer genomics and diagnostics, and RNA research and splicing.

Among the notable recent papers are:

  • Epigenetic reprogramming at estrogen-receptor binding sites alters 3D chromatin landscape in endocrine-resistant breast cancer, 2020, Nature Communications
  • Multiple links between 5-methylcytosine content of mRNA and translation, 2020, BMC Biology
  • Constitutively bound CTCF sites maintain 3D chromatin architecture and long-range epigenetically regulated domains, 2020, Nature Communications
  • Calling differentially methylated regions from whole genome bisulphite sequencing with DMRcate, 2021, Nucleic Acids Research
  • A first-in-class pan-lysyl oxidase inhibitor impairs stromal remodeling and enhances gemcitabine response and survival in pancreatic cancer, 2023, Nature Cancer

The scientist frequently collaborates with a set of co-authors, including Clare Stirzaker, Ruth Pidsley, Joanna Achinger-Kawecka, Phuc-Loi Luu, and Qian Du, reflecting sustained research partnerships.

Publications by Susan J. Clark appear regularly in several prominent venues, including bioRxiv (Cold Spring Harbor Laboratory), Nucleic Acids Research, Clinical Epigenetics, Cancers, and Pathology.

Best Publications

  • The zebrafish reference genome sequence and its relationship to the human genome.

    Kerstin Howe;Matthew D. Clark;Carlos F. Torroja;Carlos F. Torroja;James Torrance

  • High sensitivity mapping of methylated cytosines.

    S J Clark;J Harrison;C L Paul;M Frommer

  • Critical evaluation of the Illumina MethylationEPIC BeadChip microarray for whole-genome DNA methylation profiling

    Ruth Pidsley;Ruth Pidsley;Elena Zotenko;Elena Zotenko;Timothy J. Peters;Mitchell G. Lawrence

  • miRNA-dependent gene silencing involving Ago2-mediated cleavage of a circular antisense RNA

    Thomas B Hansen;Erik D Wiklund;Erik D Wiklund;Jesper B Bramsen;Sune B Villadsen

  • Bisulfite genomic sequencing: systematic investigation of critical experimental parameters

    Christoph Grunau;S. J. Clark;André Rosenthal

  • Prognostic significance of myocardial fibrosis in hypertrophic cardiomyopathy.

    Rory O'Hanlon;Agata Grasso;Michael Roughton;James C. Moon

  • De novo identification of differentially methylated regions in the human genome

    Timothy J Peters;Michael J Buckley;Aaron L Statham;Ruth Pidsley

  • Methyl-CpG-binding domain proteins: readers of the epigenome.

    Qian Du;Phuc-Loi Luu;Clare Stirzaker;Clare Stirzaker;Susan J Clark;Susan J Clark

  • Detection and measurement of PCR bias in quantitative methylation analysis of bisulphite-treated DNA

    Peter M. Warnecke;Clare Stirzaker;John R. Melki;Douglas S. Millar

  • Epigenetic remodeling in colorectal cancer results in coordinate gene suppression across an entire chromosome band

    Jordi Frigola;Jenny Song;Clare Stirzaker;Rebecca A Hinshelwood

  • Concurrent DNA hypermethylation of multiple genes in acute myeloid leukemia.

    John R. Melki;Paul C. Vincent;Susan J. Clark

  • Coordinated epigenetic repression of the miR‐200 family and miR‐205 in invasive bladder cancer

    Erik D. Wiklund;Jesper B. Bramsen;Toby Hulf;Lars Dyrskjøt

  • DNA methylation: bisulphite modification and analysis.

    Susan J Clark;Aaron Statham;Clare Stirzaker;Peter L Molloy

  • DNA methylation and gene silencing in cancer: which is the guilty party?

    Susan J Clark;Susan J Clark;Susan J Clark;John Melki;John Melki;John Melki

  • Extensive DNA Methylation Spanning the Rb Promoter in Retinoblastoma Tumors

    Clare Stirzaker;Douglas S. Millar;Cheryl L. Paul;Peter M. Warnecke

  • Identification and resolution of artifacts in bisulfite sequencing

    Peter M Warnecke;Clare Stirzaker;Jenny Song;Christoph Grunau

  • CpNpG methylation in mammalian cells

    Susan J. Clark;Janet Harrison;Marianne Frommer

  • Three-dimensional disorganization of the cancer genome occurs coincident with long-range genetic and epigenetic alterations

    Phillippa C. Taberlay;Joanna Achinger-Kawecka;Aaron T.L. Lun;Fabian A. Buske

  • Detailed methylation analysis of the glutathione S-transferase π (GSTP1) gene in prostate cancer

    Douglas S Millar;Kim K Ow;Cheryl L Paul;Pamela J Russell

  • Quantitative comparison of DNA methylation assays for biomarker development and clinical applications

    Christoph Bock;Florian Halbritter;Francisco J. Carmona;Sascha Tierling

Frequent Co-Authors

Clare Stirzaker
Clare Stirzaker Garvan Institute of Medical Research
Peter L. Molloy
Peter L. Molloy Commonwealth Scientific and Industrial Research Organisation
Mark D. Robinson
Mark D. Robinson University of Zurich
Nicola J. Armstrong
Nicola J. Armstrong Murdoch University
Alexander Swarbrick
Alexander Swarbrick Garvan Institute of Medical Research
Julia Margaret Wendy Gee
Julia Margaret Wendy Gee Cardiff University
Andrew J.S. Coats
Andrew J.S. Coats The Heart Research Institute
Neville F. Hacker
Neville F. Hacker University of New South Wales
James G. Kench
James G. Kench Royal Prince Alfred Hospital
Timothy J. Peters
Timothy J. Peters University of Bristol

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