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Biology and Biochemistry

D-Index
70
Citations
26115
World Ranking
6867
National Ranking
215

Overview

Jörg Tost is affiliated with the University of Paris-Saclay in France, focusing on research in biochemistry, genetics, and molecular biology. Their scholarly output spans several fields, with significant contributions to molecular biology, pediatrics, perinatology and child health, cancer research, and plant science. This multidisciplinary approach supports investigations into epigenetics, DNA methylation, and other molecular mechanisms underlying health and disease.

The scientist's research covers key topics including:

  • Epigenetics and DNA Methylation
  • Birth, Development, and Health
  • Health, Environment, Cognitive Aging
  • Plant Molecular Biology Research
  • Cancer Genomics and Diagnostics
  • RNA modifications and cancer
  • MicroRNA in disease regulation

Tost has coauthored publications frequently with several researchers: Johanna Lepeule, Florence Busato, Barbara Heude, Lucile Broséus, and Rémy Slama, reflecting a collaborative network within their research community.

Their work is published extensively in venues such as bioRxiv (Cold Spring Harbor Laboratory), ISEE Conference Abstracts, Epigenomics, Allergy, and Clinical Epigenetics, indicating a focus on epigenomic research and related biomedical fields.

Recent publications include:

  • Recent findings in the genetics and epigenetics of asthma and allergy, 2020, Seminars in Immunopathology
  • RNAi suppression of DNA methylation affects the drought stress response and genome integrity in transgenic poplar, 2021, New Phytologist
  • Contrasting DCIS and invasive breast cancer by subtype suggests basal-like DCIS as distinct lesions, 2020, npj Breast Cancer
  • Placental DNA methylation signatures of maternal smoking during pregnancy and potential impacts on fetal growth, 2021, Nature Communications
  • Crosstalk between microRNA expression and DNA methylation drives the hormone-dependent phenotype of breast cancer, 2021, Genome Medicine

The body of work demonstrates engagement with a variety of biological and medical research topics, including cancer subtypes, asthma and allergy genetics, plant stress biology, and the epigenetic impact of environmental factors on fetal development. Investigations often integrate molecular biology techniques such as RNA interference and DNA methylation analysis.

Best Publications

  • Pan-cancer analysis of whole genomes

    Peter J. Campbell;Gad Getz;Jan O. Korbel;Joshua M. Stuart

  • Early allopolyploid evolution in the post-Neolithic Brassica napus oilseed genome

    Boulos Chalhoub;Shengyi Liu;Isobel A.P. Parkin

  • International network of cancer genome projects

    Thomas J. Hudson;Thomas J. Hudson;Warwick Anderson;Axel Aretz;Anna D. Barker

  • DNA Methylation in Newborns and Maternal Smoking in Pregnancy: Genome-wide Consortium Meta-analysis

    Bonnie R. Joubert;Janine F. Felix;Paul Yousefi;Kelly M. Bakulski

  • Patterns of somatic structural variation in human cancer genomes

    Yilong Li;Nicola D Roberts;Jeremiah A Wala;Jeremiah A Wala;Ofer Shapira;Ofer Shapira

  • DNA methylation analysis by pyrosequencing

    Jörg Tost;Ivo G Gut

  • Complete pipeline for Infinium ® Human Methylation 450K BeadChip data processing using subset quantile normalization for accurate DNA methylation estimation

    Nizar Touleimat;Jörg Tost

  • DNA Methylation Profiling of the Human Major Histocompatibility Complex: A Pilot Study for the Human Epigenome Project

    Vardhman K Rakyan;Thomas Hildmann;Karen L Novik;Jörn Lewin

  • DNA methylation: an introduction to the biology and the disease-associated changes of a promising biomarker.

    Jörg Tost

  • Identification of Type 1 Diabetes–Associated DNA Methylation Variable Positions That Precede Disease Diagnosis

    Vardhman K. Rakyan;Huriya Beyan;Thomas A. Down;Mohammed I. Hawa

  • Analysis and quantification of multiple methylation variable positions in CpG islands by Pyrosequencing.

    Jörg Tost;Jenny Dunker;Ivo Glynne Gut

  • A DEMETER-like DNA demethylase governs tomato fruit ripening

    Ruie Liu;Alexandre How-Kit;Linda Stammitti;Emeline Teyssier

  • The epigenetics of breast cancer

    Jovana Jovanovic;Jo Anders Rønneberg;Jörg Tost;Vessela Kristensen;Vessela Kristensen

  • De novo quantitative bisulfite sequencing using the pyrosequencing technology.

    Jean-Michel Dupont;Jörg Tost;Hélène Jammes;Ivo Glynne Gut

  • Quantitative Analysis of DNA Methylation Profiles in Lung Cancer Identifies Aberrant DNA Methylation of Specific Genes and Its Association with Gender and Cancer Risk Factors

    Thomas Vaissière;Rayjean J. Hung;David Zaridze;Anush Moukeria

  • Quantitative comparison of DNA methylation assays for biomarker development and clinical applications

    Christoph Bock;Florian Halbritter;Francisco J. Carmona;Sascha Tierling

  • Specific epigenetic alterations of IGF2-H19 locus in spermatozoa from infertile men

    Céline Chalas Boissonnas;Hafida El Abdalaoui;Virginie Haelewyn;Patricia Fauque;Patricia Fauque

  • Epigenetics and allergy: from basic mechanisms to clinical applications

    Daniel P Potaczek;Hani Harb;Hani Harb;Sven Michel;Bilal Alashkar Alhamwe

  • Sex- and diet-specific changes of imprinted gene expression and DNA methylation in mouse placenta under a high-fat diet.

    Catherine Gallou-Kabani;Anne Gabory;Anne Gabory;Jörg Tost;Mohsen Karimi

  • Identification of regions correlating MGMT promoter methylation and gene expression in glioblastomas.

    Sibille Everhard;Jörg Tost;Hafida El Abdalaoui;Emmanuelle Crinière

Frequent Co-Authors

Vessela N. Kristensen
Vessela N. Kristensen Oslo University Hospital
Ivo Gut
Ivo Gut Centro Nacional de Análisis Genómico
Anne Lise Børresen-Dale
Anne Lise Børresen-Dale Oslo University Hospital
Jean-François Deleuze
Jean-François Deleuze University of Paris-Saclay
Daniel Vaiman
Daniel Vaiman Université Paris Cité
Céleste Lebbé
Céleste Lebbé Hôpitaux Universitaires Paris-Ouest
Michael Kabesch
Michael Kabesch St. Hedwig-Krankenhaus
Corinne Miceli-Richard
Corinne Miceli-Richard Université Paris Cité
Juha Pekkanen
Juha Pekkanen University at Buffalo, State University of New York

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