Wolfgang A. Linke

Overview

Best Publications

• Cardioprotection and lifespan extension by the natural polyamine spermidine

  Tobias Eisenberg;Mahmoud Abdellatif;Sabrina Schroeder;Uwe Primessnig;Uwe Primessnig

  1101
  Citations

• Myocardial structure and function differ in systolic and diastolic heart failure.

  Loek van Heerebeek;Attila Borbély;Hans W M Niessen;Jean G F Bronzwaer

  811
  Citations

• The Giant Protein Titin: A Major Player in Myocardial Mechanics, Signaling, and Disease

  Henk L. Granzier;Siegfried Labeit

  652
  Citations

• Reverse engineering of the giant muscle protein titin

  Hongbin Li;Wolfgang A. Linke;Andres F. Oberhauser;Mariano Carrion-Vazquez

  613
  Citations

• Titin mutations in iPS cells define sarcomere insufficiency as a cause of dilated cardiomyopathy

  John Travis Hinson;Anant Chopra;N. Nafissi;William Polacheck;William Polacheck

  609
  Citations

• Defined Engineered Human Myocardium With Advanced Maturation for Applications in Heart Failure Modeling and Repair.

  Malte Tiburcy;James E. Hudson;Paul Balfanz;Susanne Schlick

  571
  Citations

• Myocardial Microvascular Inflammatory Endothelial Activation in Heart Failure With Preserved Ejection Fraction

  Constantijn Franssen;Sophia Chen;Andreas Unger;H. Ibrahim Korkmaz

  519
  Citations

• The Translational Landscape of the Human Heart

  Sebastiaan van Heesch;Franziska Witte;Valentin Schneider-Lunitz;Jana F. Schulz

  488
  Citations

• Titin Isoform Switch in Ischemic Human Heart Disease

  Ciprian Neagoe;Michael Kulke;Federica del Monte;Judith K. Gwathmey

  474
  Citations

• Protein Kinase G Modulates Human Myocardial Passive Stiffness by Phosphorylation of the Titin Springs

  Martina Krüger;Sebastian Kötter;Anika Grützner;Patrick Lang

  470
  Citations

• Passive Stiffness Changes Caused by Upregulation of Compliant Titin Isoforms in Human Dilated Cardiomyopathy Hearts

  I. Makarenko;C.A. Opitz;M.C. Leake;C. Neagoe

  407
  Citations

• Sense and stretchability: The role of titin and titin-associated proteins in myocardial stress-sensing and mechanical dysfunction†

  Wolfgang A. Linke

  391
  Citations

• Gigantic business: titin properties and function through thick and thin.

  Wolfgang A. Linke;Nazha Hamdani

  385
  Citations

• Isoform Diversity of Giant Proteins in Relation to Passive and Active Contractile Properties of Rabbit Skeletal Muscles

  Lucas G. Prado;Irina Makarenko;Christian Andresen;Martina Krüger

  377
  Citations

• TOWARDS A MOLECULAR UNDERSTANDING OF THE ELASTICITY OF TITIN

  W A Linke;M Ivemeyer;N Olivieri;B Kolmerer

  352
  Citations

• Differential Cardiac Remodeling in Preload Versus Afterload

  Karl Toischer;Adam G. Rokita;Bernhard Unsöld;Wuqiang Zhu

  347
  Citations

• The Giant Protein Titin: Emerging Roles in Physiology and Pathophysiology

  Siegfried Labeit;Bernhard Kolmerer;Wolfgang A. Linke

  324
  Citations

• Myocardial Titin Hypophosphorylation Importantly Contributes to Heart Failure with Preserved Ejection Fraction in a Rat Metabolic Risk Model

  Nazha Hamdani;Constantijn Franssen;André Lourenço;Inês Falcão-Pires

  323
  Citations

• Titin-truncating variants affect heart function in disease cohorts and the general population

  Sebastian Schafer;Antonio de Marvao;Eleonora Adami;Lorna R Fiedler

  318
  Citations

• Protein Kinase G Modulates Human Myocardial Passive Stiffness By Phosphorylation Of The Titin Springs

  Martina Krueger;Sebastian Koetter;Anika Gruetzner;Patrick Lang

  4
  Citations