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Julio M. Fernandez

Julio M. Fernandez

D-Index & Metrics

Biology and Biochemistry

D-Index
44
Citations
7566
World Ranking
19283
National Ranking
7883

Overview

Julio M. Fernandez is affiliated with Columbia University in the United States and has contributed extensively to research in biochemistry, genetics, molecular biology, and physics and astronomy. Their work spans several interconnected fields of study, including atomic and molecular physics and optics, cell biology, molecular biology, cardiology and cardiovascular medicine, and plant science.

Their research emphasizes topics such as force microscopy techniques and applications, cellular mechanics and interactions, cardiomyopathy and myosin studies, biochemical and structural characterization, mechanical and optical resonators, nuclear structure and function, and plant molecular biology research.

Fernandez has published in a range of scientific venues, with frequent contributions to bioRxiv (Cold Spring Harbor Laboratory), Biophysical Journal, Proceedings of the National Academy of Sciences, Science Advances, and Nature Communications.

Recent publications include:

  • "Talin folding as the tuning fork of cellular mechanotransduction," 2020, Proceedings of the National Academy of Sciences
  • "Direct observation of a coil-to-helix contraction triggered by vinculin binding to talin," 2020, Science Advances
  • "A HaloTag-TEV genetic cassette for mechanical phenotyping of proteins from tissues," 2020, Nature Communications
  • "Protein folding modulates the chemical reactivity of a Gram-positive adhesin," 2020, Nature Chemistry
  • "Magnetic tweezers meets AFM: ultra-stable protein dynamics across the force spectrum," 2021, bioRxiv (Cold Spring Harbor Laboratory)

Frequent co-authors include Rafael Tapia-Rojo, Álvaro Alonso-Caballero, Carmen L. Badilla, Yong Li, and Andreas Unger.

Best Publications

  • Reversible Unfolding of Individual Titin Immunoglobulin Domains by AFM

    Matthias Rief;Mathias Gautel;Filipp Oesterhelt;Julio M. Fernandez

  • Stretching Single Talin Rod Molecules Activates Vinculin Binding

    Armando del Rio;Raul Perez-Jimenez;Ruchuan Liu;Pere Roca-Cusachs

  • Mechanical and Chemical Unfolding of a Single Protein: A Comparison

    Mariano Carrion-Vazquez;Andres F. Oberhauser;Susan B. Fowler;Piotr E. Marszalek

  • The molecular elasticity of the extracellular matrix protein tenascin

    Andres F. Oberhauser;Piotr E. Marszalek;Harold P. Erickson;Julio M. Fernandez

  • Mechanical unfolding intermediates in titin modules.

    Piotr E. Marszalek;Hui Lu;Hongbin Li;Mariano Carrion-Vazquez

  • Release of secretory products during transient vesicle fusion

    G. Alvarez de Toledo;R. Fernández-Chacón;J. M. Fernández

  • Force-clamp spectroscopy monitors the folding trajectory of a single protein.

    Julio M. Fernandez;Hongbin Li

  • Capacitance measurements reveal stepwise fusion events in degranulating mast cells.

    J. M. Fernandez;E. Neher;B. D. Gomperts

  • Reverse engineering of the giant muscle protein titin

    Hongbin Li;Wolfgang A. Linke;Andres F. Oberhauser;Mariano Carrion-Vazquez

  • Elastically Coupled Two-Level Systems as a Model for Biopolymer Extensibility

    Matthias Rief;Julio M. Fernandez;Hermann E. Gaub

  • Polysaccharide elasticity governed by chair–boat transitions of the glucopyranose ring

    Piotr E. Marszalek;Andres F. Oberhauser;Yuan Ping Pang;Julio M. Fernandez

  • The mechanical stability of ubiquitin is linkage dependent.

    Mariano Carrion-Vazquez;Hongbin Li;Hui Lu;Piotr E Marszalek

  • Mechanical design of proteins studied by single-molecule force spectroscopy and protein engineering.

    Mariano Carrion-Vazquez;Andres F Oberhauser;Thomas E Fisher;Piotr E Marszalek

  • Stepwise unfolding of titin under force-clamp atomic force microscopy

    Andres F. Oberhauser;Paul K. Hansma;Mariano Carrion-Vazquez;Julio M. Fernandez

  • The mechanical hierarchies of fibronectin observed with single-molecule AFM

    Andres F Oberhauser;Carmelu Badilla-Fernandez;Mariano Carrion-Vazquez;Julio M Fernandez

  • The study of protein mechanics with the atomic force microscope

    Thomas E Fisher;Andres F Oberhauser;Mariano Carrion-Vazquez;Piotr E Marszalek

  • Stretching single molecules into novel conformations using the atomic force microscope.

    Thomas E. Fisher;Piotr E. Marszalek;Julio M. Fernandez

  • Force-dependent chemical kinetics of disulfide bond reduction observed with single-molecule techniques

    Arun P. Wiita;Sri Rama Koti Ainavarapu;Hector H. Huang;Julio M. Fernandez

  • Potassium-selective single channels in guard cell protoplasts of Vicia faba

    J. I. Schroeder;R. Hedrich;J. M. Fernandez

  • Linkage between ATP consumption and mechanical unfolding during the protein processing reactions of an AAA+ degradation machine

    Jon A. Kenniston;Tania A. Baker;Julio M. Fernandez;Robert T. Sauer

Frequent Co-Authors

Hongbin Li
Hongbin Li University of British Columbia
Wolfgang A. Linke
Wolfgang A. Linke University of Münster
Bruce J. Berne
Bruce J. Berne Columbia University
Jose M. Sanchez-Ruiz
Jose M. Sanchez-Ruiz University of Granada
Arne Holmgren
Arne Holmgren Karolinska Institute
Rainer Hedrich
Rainer Hedrich University of Würzburg
Michael Urbakh
Michael Urbakh Tel Aviv University
Joseph Klafter
Joseph Klafter Tel Aviv University
Jane Clarke
Jane Clarke University of Cambridge
Brent R. Stockwell
Brent R. Stockwell Columbia University

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