2026 Arne Holmgren: Biology and Biochemistry Researcher – H-Index, Publications & Awards

Discipline name	D-Index	World Ranking	National Ranking	Publications	Citations
Biology and Biochemistry	138	302	6	466	70373

Discipline name

D-Index

World Ranking

National Ranking

Publications

Citations

Biology and Biochemistry

138

302

466

70373

Research.com Recognitions

2023 - Research.com Biology and Biochemistry in Sweden Leader Award
2022 - Research.com Biology and Biochemistry in Sweden Leader Award
Member of the European Molecular Biology Organization (EMBO)
Member of the European Molecular Biology Organization (EMBO)
Member of the European Molecular Biology Organization (EMBO)

Overview

Arne Holmgren was affiliated with the Karolinska Institute in Sweden. Their research activities focused primarily on Medicine and Biochemistry, Genetics and Molecular Biology, with particular emphasis on Molecular Biology, Oncology, Neurology, Physiology, and Cellular and Molecular Neuroscience.

Their work centered around topics such as Redox biology and oxidative stress, Metal complexes synthesis and properties, Parkinson's Disease Mechanisms and Treatments, Alzheimer's disease research and treatments, Nuclear Receptors and Signaling, Glutathione Transferases and Polymorphisms, and Selenium in Biological Systems.

Holmgren co-authored frequently with several researchers, including:

Rajib Sengupta (8 collaborations)
Lucia Coppo (7 collaborations)
Jacqueline M. Tokarew (5 collaborations)
Daniel N. El-Kodsi (5 collaborations)
Nathalie A. Lengacher (5 collaborations)

The scientist published in multiple venues, with notable contributions in:

bioRxiv (Cold Spring Harbor Laboratory) - 3 publications
The Cambridge Structural Database - 2 publications
Acta Neuropathologica - 1 publication
Frontiers in Microbiology - 1 publication
Redox Biology - 1 publication

Significant recent publications included:

"Age-associated insolubility of parkin in human midbrain is linked to redox balance and sequestration of reactive dopamine metabolites," 2021, Acta Neuropathologica
"Topical Therapeutic Efficacy of Ebselen Against Multidrug-Resistant Staphylococcus aureus LT-1 Targeting Thioredoxin Reductase," 2020, Frontiers in Microbiology
"Mitochondrial depletion of glutaredoxin 2 induces metabolic dysfunction-associated fatty liver disease in mice," 2022, Redox Biology
"Inhibition of thioredoxin reductase 1 correlates with platinum-based chemotherapeutic induced tissue injury," 2020, Biochemical Pharmacology
"Selenium Status in Diet Affects Acetaminophen-Induced Hepatotoxicity via Interruption of Redox Environment," 2020, Antioxidants and Redox Signaling

Holmgren was recognized as a member of the European Molecular Biology Organization (EMBO), an acknowledgment connected to their role and contributions in molecular biology research.

Best Publications

Physiological functions of thioredoxin and thioredoxin reductase.

Elias S. J. Arnér;Arne Holmgren

3168
Citations
Thioredoxin and glutaredoxin systems

A Holmgren

2301
Citations
The thioredoxin antioxidant system.

Jun Lu;Arne Holmgren

1872
Citations
From selenium to selenoproteins: Synthesis, identity, and their role in human health

Laura Vanda Papp;Jun Lu;Arne Holmgren;Kum Kum Khanna

1583
Citations
Thioredoxin and thioredoxin reductase.

Arne Holmgren;Mikael Bjornstedt

1125
Citations
Thioredoxin catalyzes the reduction of insulin disulfides by dithiothreitol and dihydrolipoamide.

A Holmgren

1113
Citations
Unraveling the biological roles of reactive oxygen species.

Michael P. Murphy;Arne Holmgren;Nils Göran Larsson;Barry Halliwell

918
Citations
The Role of the Thioredoxin and Glutaredoxin Pathways in Reducing Protein Disulfide Bonds in the Escherichia coliCytoplasm

William A. Prinz;Fredrik Åslund;Arne Holmgren;Jon Beckwith

883
Citations
Glutaredoxins: glutathione-dependent redox enzymes with functions far beyond a simple thioredoxin backup system.

Aristi Potamitou Fernandes;Arne Holmgren

847
Citations
Thioredoxin and related molecules--from biology to health and disease.

Christopher Horst Lillig;Arne Holmgren

842
Citations
Rat liver thioredoxin and thioredoxin reductase: purification and characterization

Mikaela Luthman;Arne Holmgren

747
Citations
Thioredoxin and thioredoxin reductase: current research with special reference to human disease.

Arne Holmgren;Jun Lu

721
Citations
The thioredoxin system in cancer.

Elias S.J. Arnér;Arne Holmgren

669
Citations
Targeting thioredoxin reductase is a basis for cancer therapy by arsenic trioxide

Jun Lu;Eng-Hui Chew;Arne Holmgren

664
Citations
Structure and mechanism of mammalian thioredoxin reductase: The active site is a redox-active selenolthiol/selenenylsulfide formed from the conserved cysteine-selenocysteine sequence

Liangwei Zhong;Elias S. J. Arnér;Arne Holmgren

658
Citations
Hydrogen donor system for Escherichia coli ribonucleoside-diphosphate reductase dependent upon glutathione

Arne Holmgren

633
Citations
Role of thioredoxin in the response of normal and transformed cells to histone deacetylase inhibitors

J. S. Ungerstedt;Y. Sowa;W.-S. Xu;Y. Shao

630
Citations
Antioxidant function of thioredoxin and glutaredoxin systems.

Arne Holmgren

623
Citations
Thioredoxin Reductase Is Irreversibly Modified by Curcumin: A NOVEL MOLECULAR MECHANISM FOR ITS ANTICANCER ACTIVITY *

Jianguo Fang;Jun Lu;Arne Holmgren

622
Citations
Three-dimensional structure of Escherichia coli thioredoxin-S2 to 2.8 A resolution

A Holmgren;B O Söderberg;H Eklund;C I Brändén

616
Citations