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Biology and Biochemistry

D-Index
71
Citations
16341
World Ranking
6723
National Ranking
3120

Overview

Bradley A. Carlson is affiliated with the National Institutes of Health in the United States. Their research primarily focuses on areas related to Selenium in Biological Systems and Birth, Development, and Health. The scientist has contributed to various subfields including Nutrition and Dietetics, Pediatrics, Perinatology and Child Health, Pharmacology, Molecular Biology, and Physiology.

Carlson's publication record includes contributions to multiple journals with a notable frequency in the International Journal of Molecular Sciences, where they have published five papers. Other publication venues include Nature Communications, Journal of Biological Chemistry, Archives of Biochemistry and Biophysics, and Frontiers in Nutrition.

Key research topics covered by Carlson encompass:

  • Selenium in Biological Systems
  • Birth, Development, and Health
  • Medical and Biological Ozone Research
  • Trace Elements in Health
  • Laser Applications in Dentistry and Medicine
  • Nuts composition and effects
  • Metabolism and Genetic Disorders

Frequent collaborators with whom Carlson has co-authored multiple works include:

  • Dolph L. Hatfield
  • K. Sandeep Prabhu
  • Shaneice K. Nettleford
  • Jisu Jung
  • Vadim N. Gladyshev

Among Carlson's recent scientific papers are:

  • "Selenophosphate synthetase 1 deficiency exacerbates osteoarthritis by dysregulating redox homeostasis", 2022, Nature Communications
  • "Selenium and the 15kDa Selenoprotein Impact Colorectal Tumorigenesis by Modulating Intestinal Barrier Integrity", 2021, International Journal of Molecular Sciences
  • "Selenium-dependent metabolic reprogramming during inflammation and resolution", 2021, Journal of Biological Chemistry
  • "Identification of Signaling Pathways for Early Embryonic Lethality and Developmental Retardation in Sephs1−/− Mice", 2021, International Journal of Molecular Sciences
  • "The Essential Role of Selenoproteins in the Resolution of Citrobacter rodentium-Induced Intestinal Inflammation", 2020, Frontiers in Nutrition

Their work addresses mechanisms involving selenoproteins and selenium's role in various physiological and pathological processes including inflammation, intestinal barrier integrity, tumorigenesis, and development. Carlson's research demonstrates an interdisciplinary approach bridging molecular biology, nutrition, and medicine to examine trace elements and their impact on health and disease.

Best Publications

  • Flavopiridol Induces G1 Arrest with Inhibition of Cyclin-dependent Kinase (CDK) 2 and CDK4 in Human Breast Carcinoma Cells

    Bradley A. Carlson;Marja M. Dubay;Edward A. Sausville;Leonardo Brizuela

  • Selenium and selenocysteine: roles in cancer, health, and development

    Dolph L. Hatfield;Petra A. Tsuji;Bradley A. Carlson;Vadim N. Gladyshev

  • A novel RNA binding protein, SBP2, is required for the translation of mammalian selenoprotein mRNAs

    Paul R. Copeland;Julia E. Fletcher;Bradley A. Carlson;Dolph L. Hatfield

  • Potent Inhibition of Cdc2 Kinase Activity by the Flavonoid L86-8275

    M. D. Losiewicz;B. A. Carlson;Gurmeet Kaur;E. A. Sausville

  • Biosynthesis of selenocysteine on its tRNA in eukaryotes

    Xue-Ming Xu;Bradley A. Carlson;Heiko Mix;Yan Zhang

  • Decoding apparatus for eukaryotic selenocysteine insertion

    Rosa M. Tujebajeva;Paul R. Copeland;Xue Ming Xu;Bradley A. Carlson

  • The kinase p38 alpha serves cell type-specific inflammatory functions in skin injury and coordinates pro- and anti-inflammatory gene expression.

    Chun Kim;Yasuyo Sano;Kristina Todorova;Bradley A Carlson

  • The essential Gcd10p–Gcd14p nuclear complex is required for 1-methyladenosine modification and maturation of initiator methionyl-tRNA

    James Anderson;Lon Phan;Rafael Cuesta;Bradley A. Carlson

  • Thioredoxin reductase 1 deficiency reverses tumor phenotype and tumorigenicity of lung carcinoma cells

    Min-Hyuk Yoo;Xue-Ming Xu;Bradley A. Carlson;Vadim N. Gladyshev

  • Rabbit beta-globin is extended beyond its UGA stop codon by multiple suppressions and translational reading gaps.

    Harold S. Chittum;William S. Lane;Bradley A. Carlson;Peter P. Roller

  • Glutathione peroxidase 4 and vitamin E cooperatively prevent hepatocellular degeneration

    Bradley A. Carlson;Ryuta Tobe;Elena Yefremova;Petra A. Tsuji

  • Neuronal selenoprotein expression is required for interneuron development and prevents seizures and neurodegeneration

    Eva K. Wirth;Marcus Conrad;Jochen Winterer;Christian Wozny

  • Selenoprotein Gene Nomenclature

    Vadim N. Gladyshev;Vadim N. Gladyshev;Elias S. Arnér;Marla J. Berry;Regina Brigelius-Flohé

  • SelT, SelW, SelH, and Rdx12: genomics and molecular insights into the functions of selenoproteins of a novel thioredoxin-like family.

    Alexander Dikiy;Sergey V. Novoselov;Dmitri E. Fomenko;Aniruddha Sengupta

  • Specific excision of the selenocysteine tRNA[Ser]Sec (Trsp) gene in mouse liver demonstrates an essential role of selenoproteins in liver function.

    Bradley A. Carlson;Sergey V. Novoselov;Easwari Kumaraswamy;Byeong Jae Lee

  • Selenocysteine incorporation machinery and the role of selenoproteins in development and health.

    Dolph L Hatfield;Bradley A Carlson;Xue-Ming Xu;Heiko Mix

  • Selenophosphate synthetase 2 is essential for selenoprotein biosynthesis.

    Xue-Ming Xu;Bradley A. Carlson;Robert Irons;Heiko Mix

  • Identification and characterization of phosphoseryl-tRNA[Ser]Sec kinase

    Bradley A. Carlson;Xue Ming Xu;Gregory V. Kryukov;Mahadev Rao;Mahadev Rao

  • Hepatically derived selenoprotein P is a key factor for kidney but not for brain selenium supply.

    Ulrich Schweizer;Florian STRECKFUß;Paco Pelt;Bradley A. Carlson

  • Inhibition of selenoprotein synthesis by selenocysteine tRNA[Ser]Sec lacking isopentenyladenosine.

    Gregory J. Warner;Marla J. Berry;Mohamed E. Moustafa;Bradley A. Carlson

Frequent Co-Authors

Dolph L. Hatfield
Dolph L. Hatfield National Institutes of Health
Vadim N. Gladyshev
Vadim N. Gladyshev Brigham and Women's Hospital
Ulrich Schweizer
Ulrich Schweizer University of Bonn
Marla J. Berry
Marla J. Berry University of Hawaii at Manoa
Gregory V. Kryukov
Gregory V. Kryukov Broad Institute
Andrew D. Patterson
Andrew D. Patterson Pennsylvania State University
Marcus Conrad
Marcus Conrad Helmholtz Zentrum München
Lino Tessarollo
Lino Tessarollo National Institutes of Health
Diane E. Handy
Diane E. Handy Brigham and Women's Hospital
Lorraine M. Sordillo
Lorraine M. Sordillo Michigan State University

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