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Matthew R. Henn

Matthew R. Henn

D-Index & Metrics

Biology and Biochemistry

D-Index
58
Citations
12458
World Ranking
13148
National Ranking
5607

Overview

Matthew R. Henn is affiliated with the Broad Institute in the United States. They have a significant number of publications primarily in the fields of Medicine and Biochemistry, Genetics, and Molecular Biology, with main research interests spanning Infectious Diseases, Molecular Biology, Epidemiology, Oncology, and Surgery.

Their research topics focus notably on Clostridium difficile and Clostridium perfringens, gut microbiota and health, microscopic colitis, inflammatory bowel disease, cancer immunotherapy and biomarkers, neutropenia and cancer infections, and nosocomial infections in intensive care units.

Key recent papers authored or co-authored by Matthew R. Henn include:

  • Fecal microbiota transplantation for the improvement of metabolism in obesity: The FMT-TRIM double-blind placebo-controlled pilot trial, 2020, PLoS Medicine
  • SER-109, an Investigational Microbiome Drug to Reduce Recurrence After Clostridioides difficile Infection: Lessons Learned From a Phase 2 Trial, 2020, Clinical Infectious Diseases
  • A Phase 1b Safety Study of SER-287, a Spore-Based Microbiome Therapeutic, for Active Mild to Moderate Ulcerative Colitis, 2020, Gastroenterology
  • Biofilms harbour Clostridioides difficile, serving as a reservoir for recurrent infection, 2021, npj Biofilms and Microbiomes
  • Randomized Placebo-Controlled, Biomarker-Stratified Phase Ib Microbiome Modulation in Melanoma: Impact of Antibiotic Preconditioning on Microbiome and Immunity, 2024, Cancer Discovery

Matthew R. Henn frequently collaborates with other researchers, including Christopher B. Ford, Jennifer R. Wortman, Jessica A. Bryant, Meghan Chafee, and Lisa Von Moltke.

Their work has been published most extensively in the following venues:

  • Gastroenterology
  • Journal of Clinical Oncology
  • Open Forum Infectious Diseases
  • Transplantation and Cellular Therapy
  • Clinical Infectious Diseases

The diversity of publication venues reflects a broad engagement across medical and biological disciplines. The primary focus on microbial therapeutics, infectious agents, and cancer-related immunology underscores the translational aspect of their research contributing to both clinical and molecular understandings.

Best Publications

  • The major genetic determinants of HIV-1 control affect HLA class I peptide presentation

    Pereyra F;Jia X;McLaren Pj

  • NATURALLY OCCURRING DOMINANT RESISTANCE MUTATIONS TO HEPATITIS C VIRUS PROTEASE AND POLYMERASE INHIBITORS IN TREATMENT-NAIVE PATIENTS

    Thomas Kuntzen;Joerg Timm;Andrew Berical;Niall Lennon

  • Whole genome deep sequencing of HIV-1 reveals the impact of early minor variants upon immune recognition during acute infection

    Matthew R. Henn;Christian L. Boutwell;Patrick Charlebois;Niall J Lennon

  • Genomics of the fungal kingdom: Insights into eukaryotic biology

    James E. Galagan;Matthew R. Henn;Li-Jun Ma;Christina A. Cuomo

  • Comparative genomic analyses of the human fungal pathogens Coccidioides and their relatives

    Thomas J. Sharpton;Jason E. Stajich;Steven D. Rounsley;Malcolm J. Gardner

  • Dynamics of Dengue Disease Severity Determined by the Interplay Between Viral Genetics and Serotype-Specific Immunity

    Molly OhAinle;Angel Balmaseda;Alexander R. Macalalad;Yolanda Tellez

  • Genomic analysis of oceanic cyanobacterial myoviruses compared with T4-like myoviruses from diverse hosts and environments

    Matthew B. Sullivan;Matthew B. Sullivan;Katherine H. Huang;Julio C. Ignacio-Espinoza;Aaron M. Berlin

  • Whole genome amplification and de novo assembly of single bacterial cells.

    Sébastien Rodrigue;Rex R. Malmstrom;Aaron M. Berlin;Bruce W. Birren

  • A Novel Microbiome Therapeutic Increases Gut Microbial Diversity and Prevents Recurrent Clostridium difficile Infection

    Sahil Khanna;Darrell S. Pardi;Colleen R. Kelly;Colleen S. Kraft

  • Short-Term Temporal Variability in Airborne Bacterial and Fungal Populations

    Noah Fierer;Noah Fierer;Zongzhi Liu;Mari Rodríguez-Hernández;Rob Knight

  • Synergistic bacterial compositions and methods of production and use thereof

    Matthew R. Henn;Geoffrey von Maltzahn;Anthony Mario D'Onofrio;Kevin Daniel Litcofsky

  • Enabling a community to dissect an organism: overview of the Neurospora functional genomics project.

    Jay C. Dunlap;Katherine A. Borkovich;Matthew R. Henn;Gloria E. Turner

  • Rapid diversification of coevolving marine Synechococcus and a virus

    Marcia F. Marston;Francis J. Pierciey;Alicia Shepard;Gary Gearin

  • The GAAS metagenomic tool and its estimations of viral and microbial average genome size in four major biomes.

    Florent E. Angly;Dana Willner;Alejandra Prieto-Davó;Robert A. Edwards;Robert A. Edwards

  • Fecal microbiota transplantation for the improvement of metabolism in obesity: The FMT-TRIM double-blind placebo-controlled pilot trial

    Elaine W. Yu;Liu Gao;Petr Stastka;Michael C. Cheney

  • Population genomic sequencing of Coccidioides fungi reveals recent hybridization and transposon control

    Daniel E. Neafsey;Bridget M. Barker;Thomas J. Sharpton;Jason E. Stajich

  • De novo assembly of highly diverse viral populations

    Xiao Yang;Patrick Charlebois;Sante Gnerre;Matthew G Coole

  • Ectomycorrhizal fungi introduced with exotic pine plantations induce soil carbon depletion

    Ignacio H. Chapela;Laurie J. Osher;Thomas R. Horton;Matthew R. Henn

  • Comparative Genomic Analysis of Human Fungal Pathogens Causing Paracoccidioidomycosis

    Christopher A. Desjardins;Mia D. Champion;Jason W. Holder;Jason W. Holder;Anna Muszewska

  • Fecal microbiota transplantation for the improvement of metabolism in obesity: The FMT-TRIM double-blind placebo-controlled pilot trial

    Yu Ew;Gao L;Stastka P;Cheney Mc

Frequent Co-Authors

Jennifer R. Wortman
Jennifer R. Wortman Broad Institute
Niall J. Lennon
Niall J. Lennon Broad Institute
Bruce W. Birren
Bruce W. Birren Broad Institute
Todd M. Allen
Todd M. Allen Harvard University
David A. Cook
David A. Cook Mayo Clinic
Sarah Young
Sarah Young University of North Georgia
Bruce D. Walker
Bruce D. Walker Harvard University
Qiandong Zeng
Qiandong Zeng LabCorp (United States)
Edward C. Holmes
Edward C. Holmes University of Sydney
James E. Galagan
James E. Galagan Boston University

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