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Jennifer R. Wortman

Jennifer R. Wortman

D-Index & Metrics

Biology and Biochemistry

D-Index
85
Citations
110781
World Ranking
3048
National Ranking
1549

Overview

Jennifer R. Wortman is affiliated with the Broad Institute in the United States. Their research spans multiple fields within medicine and biochemistry, genetics, and molecular biology, with notable focus on infectious diseases, oncology, molecular biology, epidemiology, and psychiatry and mental health.

Their work includes a significant emphasis on gut microbiota and health, Clostridium difficile and Clostridium perfringens research, cancer immunotherapy and biomarkers, microscopic colitis, cancer, stress, anesthesia, and immune response, as well as nosocomial infections and neutropenia in cancer patients.

Recent publications by Jennifer R. Wortman include the following:

  • SER-109, an Investigational Microbiome Drug to Reduce Recurrence After Clostridioides difficile Infection: Lessons Learned From a Phase 2 Trial, 2020, Clinical Infectious Diseases
  • A Phase 1b Safety Study of SER-287, a Spore-Based Microbiome Therapeutic, for Active Mild to Moderate Ulcerative Colitis, 2020, Gastroenterology
  • Randomized Placebo-Controlled, Biomarker-Stratified Phase Ib Microbiome Modulation in Melanoma: Impact of Antibiotic Preconditioning on Microbiome and Immunity, 2024, Cancer Discovery
  • Intervention strategies for microbial therapeutics in cancer immunotherapy, 2020, Immuno-Oncology Technology
  • 607 MCGRAW trial: evaluation of the safety and efficacy of an oral microbiome intervention (SER-401) in combination with nivolumab in first line metastatic melanoma patients, 2022, Regular and Young Investigator Award Abstracts

The most frequent co-authors collaborating with Jennifer R. Wortman include:

  • Matthew R. Henn
  • Christopher B. Ford
  • Kevin Litcofsky
  • John Auniņš
  • Barbara McGovern

Their work is published mainly in the following venues:

  • Gastroenterology
  • Clinical Infectious Diseases
  • Cancer Discovery
  • Immuno-Oncology Technology
  • Regular and Young Investigator Award Abstracts

Jennifer R. Wortman's contributions bridge clinical and molecular approaches, particularly within therapeutic microbiome research in diseases such as ulcerative colitis, Clostridioides difficile infection, and melanoma. The multidisciplinary nature of their research reflects integration of molecular biology techniques and clinical trial methodologies.

Best Publications

  • The Sequence of the Human Genome

    J. Craig Venter;Mark D. Adams;Eugene W. Myers;Peter W. Li

  • Structure, function and diversity of the healthy human microbiome

    Curtis Huttenhower;Curtis Huttenhower;Dirk Gevers;Rob Knight;Rob Knight;Sahar Abubucker

  • The genome sequence of Drosophila melanogaster

    M. D. Adams;S. E. Celniker;R. A. Holt;C. A. Evans

  • Pilon: An Integrated Tool for Comprehensive Microbial Variant Detection and Genome Assembly Improvement

    Bruce J. Walker;Thomas Abeel;Terrance Shea;Margaret Priest

  • The Gene Ontology (GO) database and informatics resource.

    Harris Ma;Clark J;Ireland A;Lomax J

  • Automated eukaryotic gene structure annotation using EVidenceModeler and the Program to Assemble Spliced Alignments

    Brian J Haas;Brian J Haas;Steven L Salzberg;Wei Zhu;Mihaela Pertea

  • A framework for human microbiome research

    Barbara A. Methé;Karen E. Nelson;Mihai Pop;Heather H. Creasy

  • The Genome Sequence of the Malaria Mosquito Anopheles gambiae

    Robert A. Holt;G. Mani Subramanian;Aaron Halpern;Granger G. Sutton

  • Comparative Genomics of the Eukaryotes

    Gerald M. Rubin;Mark D. Yandell;Jennifer R. Wortman;George L. Gabor

  • The Genome of the African Trypanosome Trypanosoma brucei

    Matthew Berriman;Elodie Ghedin;Elodie Ghedin;Christiane Hertz-Fowler;Gaelle Blandin

  • Improving the Arabidopsis genome annotation using maximal transcript alignment assemblies

    Brian J. Haas;Arthur L. Delcher;Stephen M. Mount;Jennifer R. Wortman

  • The genome sequence of Trypanosoma cruzi, etiologic agent of Chagas disease

    Najib M. El-Sayed;Peter J. Myler;Peter J. Myler;Daniella C. Bartholomeu;Daniel Nilsson

  • Genomic sequence of the pathogenic and allergenic filamentous fungus Aspergillus fumigatus

    William C. Nierman;William C. Nierman;Arnab Pain;Michael J. Anderson;Jennifer R. Wortman;Jennifer R. Wortman

  • Sequencing of Aspergillus nidulans and comparative analysis with A. fumigatus and A. oryzae

    James E. Galagan;Sarah E. Calvo;Christina Cuomo;Li Jun Ma

  • Genome sequencing and analysis of Aspergillus oryzae

    Masayuki Machida;Kiyoshi Asai;Motoaki Sano;Toshihiro Tanaka

  • The TIGR Rice Genome Annotation Resource: Improvements and New Features

    Shu Ouyang;Wei Zhu;John A. Hamilton;Haining Lin

  • Genome sequence of Aedes aegypti, a major arbovirus vector

    Vishvanath Nene;Jennifer R. Wortman;Daniel Lawson;Brian Haas

  • The genome of the blood fluke Schistosoma mansoni

    Matthew Berriman;Brian J. Haas;Brian J. Haas;Philip T. LoVerde;R. Alan Wilson

  • Draft genome sequence of the sexually transmitted pathogen Trichomonas vaginalis

    Jane M. Carlton;Robert . Hirt;Joana C. Silva;Arthur L. Delcher

  • Comparative genomics of trypanosomatid parasitic protozoa.

    Najib M. El-Sayed;Peter J. Myler;Peter J. Myler;Gaëlle Blandin;Matthew Berriman

Frequent Co-Authors

Brian J. Haas
Brian J. Haas Broad Institute
Gustavo C. Cerqueira
Gustavo C. Cerqueira Broad Institute
Steven L. Salzberg
Steven L. Salzberg Johns Hopkins University
Bruce W. Birren
Bruce W. Birren Broad Institute
Gustavo H. Goldman
Gustavo H. Goldman Universidade de São Paulo
Qiandong Zeng
Qiandong Zeng LabCorp (United States)
Matthew R. Henn
Matthew R. Henn Broad Institute
David B. Archer
David B. Archer University of Nottingham
Gavin Sherlock
Gavin Sherlock Stanford University
William C. Nierman
William C. Nierman J. Craig Venter Institute

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