World's Best Scientists 2026 revealed!

D-Index & Metrics

Chemistry

D-Index
68
Citations
16982
World Ranking
6504
National Ranking
1978

Research.com Recognitions

  • 2003 - Fellow of the American Association for the Advancement of Science (AAAS)
  • 2003 - Fellow of the American Academy of Arts and Sciences
  • 1998 - Member of the National Academy of Sciences

Overview

Perry A. Frey is affiliated with the University of Wisconsin-Madison in the United States. Their research primarily spans the fields of biochemistry, genetics, molecular biology, and medicine, with notable contributions in specific subfields such as molecular biology, rheumatology, and inorganic chemistry.

The scientist's recent publications include:

  • Electron Spin Echo Envelope Modulation Spectroscopy Reveals How Adenosylcobalamin-Dependent Lysine 5,6-Aminomutase Positions the Radical Pair Intermediates and Modulates Their Stabilities for Efficient Catalysis, 2021, ACS Catalysis
  • How are Vitamin B12 and S-Adenosylmethionine Related?, 2021, Internal Medicine Research - Open Journal

Frequent coauthors collaborating with Perry A. Frey comprise:

  • Junru Chen
  • Ting-Xi Ke
  • Shyue-Chu Ke
  • Samuel E. Butcher
  • George H. Reed

The venues where Perry A. Frey has published recently are:

  • ACS Catalysis
  • Internal Medicine Research - Open Journal

Main topics covered in Frey's research work include:

  • Porphyrin Metabolism and Disorders
  • Folate and B Vitamins Research
  • Metal-Catalyzed Oxygenation Mechanisms
  • RNA and protein synthesis mechanisms
  • CRISPR and Genetic Engineering
  • RNA modifications and cancer

The scientist's recognitions include:

  • Fellow of the American Association for the Advancement of Science (AAAS), 2003
  • Fellow of the American Academy of Arts and Sciences, 2003
  • Member of the National Academy of Sciences, 1998

Best Publications

  • A low-barrier hydrogen bond in the catalytic triad of serine proteases

    Perry A. Frey;Sean A. Whitt;John B. Tobin

  • The Low Barrier Hydrogen Bond in Enzymatic Catalysis

    W. Wallace Cleland;Perry A. Frey;John A. Gerlt

  • The Leloir pathway: a mechanistic imperative for three enzymes to change the stereochemical configuration of a single carbon in galactose

    Perry A. Frey

  • The Radical SAM Superfamily

    Perry A. Frey;Adrian D. Hegeman;Frank J. Ruzicka

  • Understanding enzymic catalysis: the importance of short, strong hydrogen bonds.

    John A. Gerlt;Maurice M. Kreevoy;W.W. Cleland;Perry A. Frey

  • Enzymatic reaction mechanisms

    Perry A. Frey;Adrian D. Hegeman

  • On low-barrier hydrogen bonds and enzyme catalysis. Authors' reply

    A. Warshel;A. Papazyan;P. A. Kollman;W. W. Cleland

  • The ubiquity of iron.

    Perry A. Frey;George H. Reed

  • S-Adenosylmethionine: a wolf in sheep's clothing, or a rich man's adenosylcobalamin?

    Perry A. Frey;Olafur Th. Magnusson

  • Radical mechanisms of enzymatic catalysis.

    Perry A. Frey

  • A NEW CONCEPT FOR THE MECHANISM OF ACTION OF CHYMOTRYPSIN : THE ROLE OF THE LOW-BARRIER HYDROGEN BOND

    Constance S. Cassidy;Jing Lin;Perry A. Frey

  • S-adenosylmethionine as an oxidant : the radical SAM superfamily

    Susan C. Wang;Perry A. Frey

  • Bond order and charge localization in nucleoside phosphorothioates.

    Unknown

  • Molecular structure of the NADH/UDP-glucose abortive complex of UDP-galactose 4-epimerase from Escherichia coli: implications for the catalytic mechanism.

    James B. Thoden;Perry A. Frey;Hazel M. Holden

  • The x-ray crystal structure of lysine-2,3-aminomutase from Clostridium subterminale

    Bryan W. Lepore;Frank J. Ruzicka;Perry A. Frey;Dagmar Ringe

  • Mechanistic roles of tyrosine 149 and serine 124 in UDP-galactose 4-epimerase from Escherichia coli.

    Yijeng Liu;James B. Thoden;Jeongmin Kim;Elizabeth Berger

  • The role of S-adenosylmethionine in the lysine 2,3-aminomutase reaction.

    M Moss;P A Frey

  • Studies on the Mechanism of Action of Cobamide Coenzymes CHEMICAL PROPERTIES OF THE ENZYME-COENZYME COMPLEX

    O.W. Wagner;H.A. Lee;P.A. Frey;R.H. Abeles

  • Importance of organic radicals in enzymic cleavage of unactivated carbon-hydrogen bonds

    Perry A. Frey

  • Free radical mechanisms in enzymology.

    Perry A. Frey;and Adrian D. Hegeman;George H. Reed

  • S-adenosylmethionine-dependent reduction of lysine 2,3-aminomutase and observation of the catalytically functional iron-sulfur centers by electron paramagnetic resonance

    Kafryn W. Lieder;Squire Booker;Frank J. Ruzicka;Helmut Beinert

  • The stereochemistry of the conversion of D and L 1,2-propanediols to propionaldehyde.

    Unknown

Frequent Co-Authors

John P. Richard
John P. Richard University at Buffalo, State University of New York
Joseph S. Wall
Joseph S. Wall Brookhaven National Laboratory
Squire J. Booker
Squire J. Booker Pennsylvania State University
Robert H. Abeles
Robert H. Abeles Brandeis University
Ivan Rayment
Ivan Rayment University of Wisconsin–Madison
James B. Thoden
James B. Thoden University of Wisconsin–Madison
Ming-Daw Tsai
Ming-Daw Tsai Academia Sinica
Hazel M. Holden
Hazel M. Holden University of Wisconsin–Madison
Fritz Eckstein
Fritz Eckstein Max Planck Society
Merton F. Utter
Merton F. Utter Case Western Reserve University

If you think any of the details on this page are incorrect, let us know.

Report an issue

We appreciate your kind effort to assist us to improve this page, it would be helpful providing us with as much detail as possible in the text box below:

Related Online Degrees & Career Pathways

Studying Chemistry in the USA often opens doors to diverse career fields, including forensic science and legal support roles. For those interested in applying chemistry knowledge to criminal investigations, exploring careers in forensics can be a great option. Forensic scientists analyze chemical evidence to help solve crimes, blending scientific expertise with investigative work.

Many students choose to pursue flexible and affordable options such as online degrees. When considering programs, understanding how much is criminal justice degree is crucial for planning. Online criminal justice degrees offer an accessible pathway that complements science skills.

For those seeking entry-level roles or aiming to transfer to a bachelor’s program, the best online associate degree programs in criminal justice provide solid grounding in legal and investigative principles relevant to chemistry-focused careers.

Additionally, if your interest lies in legal documentation or support, pursuing a paralegal associate degree can offer rewarding career pathways that complement a scientific background, enhancing your versatility in the job market.

Best Scientists Citing Perry A. Frey

Trending Scientists

Recently Published Articles