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Chemistry

D-Index
55
Citations
8212
World Ranking
12401
National Ranking
3302

Overview

E. Neil G. Marsh is affiliated with the University of Michigan-Ann Arbor in the United States. Their research primarily lies within the fields of Biochemistry, Genetics and Molecular Biology, with a particular focus on Molecular Biology, Immunology, Biotechnology, Cell Biology, and Biochemistry as subfields.

The scientist's work addresses a variety of topics including interferon and immune responses, biochemical and biochemical processes, RNA modifications and cancer, microbial metabolic engineering and bioproduction, RNA regulation and disease, biochemical acid research studies, and enzyme catalysis and immobilization.

Recent published papers cover diverse areas of cellular metabolism, immunology, and enzyme activity. Key publications include:

  • Viperin: An ancient radical SAM enzyme finds its place in modern cellular metabolism and innate immunity (2020), Journal of Biological Chemistry
  • Giving superabsorbent polymers a second life as pressure-sensitive adhesives (2021), Nature Communications
  • Viperin binds STING and enhances the type-I interferon response following dsDNA detection (2020), Immunology and Cell Biology
  • Targeting viperin to the mitochondrion inhibits the thiolase activity of the trifunctional enzyme complex (2020), Journal of Biological Chemistry
  • Interactions between Viperin, Vesicle-Associated Membrane Protein A, and Hepatitis C Virus Protein NS5A Modulate Viperin Activity and NS5A Degradation (2020), Biochemistry

Frequently publishing in journals with a focus on biochemical and physical chemistry topics, E. Neil G. Marsh often contributes to the following venues:

  • Journal of Biological Chemistry
  • Faraday Discussions
  • Biochemistry
  • bioRxiv (Cold Spring Harbor Laboratory)
  • The Journal of Physical Chemistry B

The scientist frequently collaborates with several coauthors, including:

  • Prathamesh M. Datar
  • Ayesha M. Patel
  • Soumi Ghosh
  • Arti B. Dumbrepatil
  • Robert T. Kennedy

Best Publications

  • Role of Zinc in Human Islet Amyloid Polypeptide Aggregation

    Jeffrey R Brender;Kevin Hartman;Ravi Prakash Reddy Nanga;Nataliya Popovych

  • Using 19F NMR to Probe Biological Interactions of Proteins and Peptides

    E. Neil G. Marsh;Yuta Suzuki

  • Fluorinated proteins: From design and synthesis to structure and stability

    E Neil G Marsh

  • Immobilized enzymes: understanding enzyme – surface interactions at the molecular level

    Marie Hoarau;Somayesadat Badieyan;E. Neil G. Marsh

  • Alternative Pathways of Human Islet Amyloid Polypeptide Aggregation Distinguished by 19F Nuclear Magnetic Resonance-Detected Kinetics of Monomer Consumption

    Yuta Suzuki;Jeffrey R. Brender;Kevin Hartman;Ayyalusamy Ramamoorthy

  • Cloning and sequencing of glutamate mutase component S from Clostridium tetanomorphum. Homologies with other cobalamin-dependent enzymes.

    E.Neil G. Marsh;Daniel E. Holloway

  • Coupling of cobalt-carbon bond homolysis and hydrogen atom abstraction in adenosylcobalamin-dependent glutamate mutase.

    E. N. G. Marsh;D. P. Ballou

  • Fluorous effect in proteins: De novo design and characterization of a four-α-helix bundle protein containing hexafluoroleucine

    Kyung Hoon Lee;Hyang Yeol Lee;Morris M. Slutsky;James T. Anderson

  • Modulating protein structure with fluorous amino acids: increased stability and native-like structure conferred on a 4-helix bundle protein by hexafluoroleucine.

    Hyang Yeol Lee;Kyung Hoon Lee;Hashim M. Al-Hashimi;E. Neil G. Marsh

  • Adenosyl radical: reagent and catalyst in enzyme reactions

    E. Neil G. Marsh;Dustin P. Patterson;Lei Li

  • Two isozymes of clavaminate synthase central to clavulanic acid formation: cloning and sequencing of both genes from Streptomyces clavuligerus.

    E. Neil Marsh;Margaret Dah Tsyr Chang;Craig A. Townsend

  • Resolution of oligomeric species during the aggregation of Aβ1-40 using (19)F NMR.

    Yuta Suzuki;Jeffrey R. Brender;Molly T. Soper;Janarthanan Krishnamoorthy

  • Adenosylcobalamin-dependent isomerases: new insights into structure and mechanism.

    E.Neil G Marsh;Catherine L Drennan

  • Oxygen‐Independent Decarbonylation of Aldehydes by Cyanobacterial Aldehyde Decarbonylase: A New Reaction of Diiron Enzymes

    Debasis Das;Bekir E. Eser;Jaehong Han;Aaron Sciore

  • Using Fluorous Amino Acids To Probe the Effects of Changing Hydrophobicity on the Physical and Biological Properties of the β-Hairpin Antimicrobial Peptide Protegrin-1†

    Lindsey M. Gottler;Roberto de la Salud Bea;Charles E. Shelburne;Ayyalusamy Ramamoorthy

  • Using Fluorous Amino Acids to Modulate the Biological Activity of an Antimicrobial Peptide

    Lindsey M. Gottler;Hyang Yeol Lee;Charles E. Shelburne;Ayyalusamy Ramamoorthy

  • Identification of a Flavin:NADH Oxidoreductase Involved in the Biosynthesis of Actinorhodin PURIFICATION AND CHARACTERIZATION OF THE RECOMBINANT ENZYME

    Steven G. Kendrew;Stephen E. Harding;David A. Hopwood;E. Neil G. Marsh

  • High-resolution NMR characterization of low abundance oligomers of amyloid-β without purification

    Samuel A. Kotler;Jeffrey R. Brender;Subramanian Vivekanandan;Yuta Suzuki

  • Structural basis for the enhanced stability of highly fluorinated proteins

    Benjamin C. Buer;Jennifer L. Meagher;Jeanne A. Stuckey;E. Neil G. Marsh

  • Isofunctional Enzymes PAD1 and UbiX Catalyze Formation of a Novel Cofactor Required by Ferulic Acid Decarboxylase and 4-Hydroxy-3-polyprenylbenzoic Acid Decarboxylase

    Fengming Lin;Kyle L. Ferguson;David R. Boyer;Xiaoxia Nina Lin

  • Production of Propane and Other Short-Chain Alkanes by Structure-Based Engineering of Ligand Specificity in Aldehyde-Deformylating Oxygenase

    Basile Khara;Navya Menon;Colin Levy;DavidJ. Mansell

Frequent Co-Authors

Zhan Chen
Zhan Chen University of Michigan–Ann Arbor
Robert T. Kennedy
Robert T. Kennedy University of Michigan–Ann Arbor
Mark M. Banaszak Holl
Mark M. Banaszak Holl Monash University
James C. A. Bardwell
James C. A. Bardwell University of Michigan–Ann Arbor
Ayyalusamy Ramamoorthy
Ayyalusamy Ramamoorthy Florida State University
Brandon T. Ruotolo
Brandon T. Ruotolo University of Michigan–Ann Arbor
Charles L. Brooks
Charles L. Brooks University of Michigan–Ann Arbor
Jeffrey R. Brender
Jeffrey R. Brender National Institutes of Health
Jeanne A. Stuckey
Jeanne A. Stuckey University of Michigan–Ann Arbor

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