D-Index & Metrics Best Publications

D-Index & Metrics

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Chemistry D-index 106 Citations 49,134 352 World Ranking 353 National Ranking 171

Overview

What is he best known for?

The fields of study he is best known for:

  • Quantum mechanics
  • Enzyme
  • Gene

The scientist’s investigation covers issues in Molecular dynamics, Statistical physics, Crystallography, Computational chemistry and Protein folding. His Molecular dynamics research is multidisciplinary, relying on both Protein structure, Dihedral angle, Chemical physics and Thermodynamics. He focuses mostly in the field of Statistical physics, narrowing it down to matters related to Solvation and, in some cases, Poisson–Boltzmann equation, Function and Poisson distribution.

His studies deal with areas such as Biophysics and Capsid as well as Crystallography. His Computational chemistry research is multidisciplinary, incorporating elements of Solvent effects and Potential energy. His studies in Protein folding integrate themes in fields like Folding, Ab initio, Molecular model and Protein topology.

His most cited work include:

  • CHARMM: the biomolecular simulation program. (4881 citations)
  • Extending the treatment of backbone energetics in protein force fields: limitations of gas-phase quantum mechanics in reproducing protein conformational distributions in molecular dynamics simulations. (2578 citations)
  • Detailed analysis of grid-based molecular docking: A case study of CDOCKER-A CHARMm-based MD docking algorithm. (918 citations)

What are the main themes of his work throughout his whole career to date?

Charles L. Brooks mostly deals with Molecular dynamics, Crystallography, Protein structure, Protein folding and Biophysics. Molecular dynamics is a subfield of Computational chemistry that Charles L. Brooks investigates. He has included themes like Solvation and Solvent models in his Computational chemistry study.

His Crystallography research focuses on Capsid and how it relates to Icosahedral symmetry. His Protein structure study frequently draws parallels with other fields, such as Peptide sequence. His study in Protein folding is interdisciplinary in nature, drawing from both Folding, Native state and Energy landscape.

He most often published in these fields:

  • Molecular dynamics (33.60%)
  • Crystallography (24.45%)
  • Protein structure (16.90%)

What were the highlights of his more recent work (between 2012-2021)?

  • Molecular dynamics (33.60%)
  • Biophysics (15.51%)
  • Crystallography (24.45%)

In recent papers he was focusing on the following fields of study:

His primary scientific interests are in Molecular dynamics, Biophysics, Crystallography, Protein structure and Biochemistry. Molecular dynamics is a subfield of Computational chemistry that Charles L. Brooks explores. Charles L. Brooks has researched Computational chemistry in several fields, including Solvent models and Solvation.

His Biophysics research incorporates themes from RNA, Chaperone, Small molecule, Side chain and Allosteric regulation. The concepts of his Protein structure study are interwoven with issues in Biological system and Protein folding. His Protein folding study combines topics from a wide range of disciplines, such as Native state and Computational biology.

Between 2012 and 2021, his most popular works were:

  • CHARMM-GUI Input Generator for NAMD, Gromacs, Amber, Openmm, and CHARMM/OpenMM Simulations using the CHARMM36 Additive Force Field (880 citations)
  • Hierarchy of RNA functional dynamics (100 citations)
  • Crowding induced collective hydration of biological macromolecules over extended distances. (85 citations)

In his most recent research, the most cited papers focused on:

  • Quantum mechanics
  • Enzyme
  • Gene

Charles L. Brooks mainly investigates Molecular dynamics, Biophysics, Protein structure, Computational chemistry and Crystallography. His studies deal with areas such as Chemical physics, RNA, Protonation, Combinatorial chemistry and Peptide as well as Molecular dynamics. The study incorporates disciplines such as Endosome, Biochemistry, Small molecule, Binding site and Lipid bilayer in addition to Biophysics.

His research in Protein structure intersects with topics in Plasma protein binding, Stereochemistry, Chaperone and Enzyme. Charles L. Brooks studies Force field, a branch of Computational chemistry. The Crystallography study combines topics in areas such as Base pair, Conformational change, Ribosome and Protein folding.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

CHARMM: the biomolecular simulation program.

B. R. Brooks;C. L. Brooks;A. D. Mackerell;L. Nilsson.
Journal of Computational Chemistry (2009)

5859 Citations

Extending the treatment of backbone energetics in protein force fields: limitations of gas-phase quantum mechanics in reproducing protein conformational distributions in molecular dynamics simulations.

Alexander D. Mackerell;Michael Feig;Charles L. Brooks.
Journal of Computational Chemistry (2004)

2578 Citations

Proteins: A Theoretical Perspective of Dynamics, Structure, and Thermodynamics

C. L. Brooks;M. Karplus;B. Montgomery Pettitt;Robert H. Austin.
(1988)

1206 Citations

Detailed analysis of grid-based molecular docking: A case study of CDOCKER-A CHARMm-based MD docking algorithm.

Guosheng Wu;Daniel H. Robertson;Charles L. Brooks;Michal Vieth.
Journal of Computational Chemistry (2003)

1189 Citations

CHARMM-GUI Input Generator for NAMD, Gromacs, Amber, Openmm, and CHARMM/OpenMM Simulations using the CHARMM36 Additive Force Field

Jumin Lee;Xi Cheng;Jason M. Swails;Min Sun Yeom.
Journal of Chemical Theory and Computation (2016)

1087 Citations

Improved treatment of the protein backbone in empirical force fields.

Alexander D. MacKerell;Michael Feig;Charles L. Brooks.
Journal of the American Chemical Society (2004)

883 Citations

MMTSB Tool Set: enhanced sampling and multiscale modeling methods for applications in structural biology

Michael Feig;John Karanicolas;Charles L. Brooks.
Journal of Molecular Graphics & Modelling (2004)

864 Citations

A modified TIP3P water potential for simulation with Ewald summation.

Daniel J. Price;Charles L. Brooks.
Journal of Chemical Physics (2004)

723 Citations

CHARMM: The Energy Function and Its Parameterization

Alexander D. MacKerell;Bernard Brooks;Charles L. Brooks;Lennart Nilsson.
Encyclopedia of Computational Chemistry (2002)

711 Citations

Generalized born model with a simple smoothing function

Wonpil Im;Michael S. Lee;Charles L. Brooks.
Journal of Computational Chemistry (2003)

709 Citations

Best Scientists Citing Charles L. Brooks

Alexander D. MacKerell

Alexander D. MacKerell

University of Maryland, Baltimore

Publications: 193

Martin Karplus

Martin Karplus

Harvard University

Publications: 192

Ruth Nussinov

Ruth Nussinov

U.S. Department of Health and Human Services

Publications: 155

Benoît Roux

Benoît Roux

University of Chicago

Publications: 137

Klaus Schulten

Klaus Schulten

University of Illinois at Urbana-Champaign

Publications: 121

Wonpil Im

Wonpil Im

Lehigh University

Publications: 121

Amedeo Caflisch

Amedeo Caflisch

University of Zurich

Publications: 104

Qiang Cui

Qiang Cui

Boston University

Publications: 103

J. Andrew McCammon

J. Andrew McCammon

University of California, San Diego

Publications: 101

Jeremy C. Smith

Jeremy C. Smith

University of Tennessee at Knoxville

Publications: 100

Bernard R. Brooks

Bernard R. Brooks

National Institutes of Health

Publications: 99

Michael Feig

Michael Feig

Michigan State University

Publications: 97

Markus Meuwly

Markus Meuwly

University of Basel

Publications: 93

Vijay S. Pande

Vijay S. Pande

Stanford University

Publications: 91

John Z. H. Zhang

John Z. H. Zhang

East China Normal University

Publications: 86

Ruhong Zhou

Ruhong Zhou

Zhejiang University

Publications: 86

Profile was last updated on December 6th, 2021.
Research.com Ranking is based on data retrieved from the Microsoft Academic Graph (MAG).
The ranking d-index is inferred from publications deemed to belong to the considered discipline.

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