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Chemistry

D-Index
65
Citations
15146
World Ranking
7659
National Ranking
2241

Overview

Brandon T. Ruotolo is affiliated with the University of Michigan-Ann Arbor in the United States. Their research primarily centers on the fields of biochemistry, genetics, molecular biology, and chemistry, with a strong emphasis on spectroscopy. The main subfields of study include spectroscopy, molecular biology, biomedical engineering, computational mechanics, and materials chemistry.

The researcher's work covers several key topics, notably mass spectrometry techniques and applications, analytical chemistry and chromatography, advanced proteomics techniques and applications, metabolomics and mass spectrometry studies, protein purification and stability, RNA and protein synthesis mechanisms, and ion-surface interactions and analysis.

Brandon T. Ruotolo has contributed to a range of recent scholarly articles, demonstrating ongoing engagement with the scientific community. Selected publications include:

  • An Improved Calibration Approach for Traveling Wave Ion Mobility Spectrometry: Robust, High-Precision Collision Cross Sections (2021, Analytical Chemistry)
  • Enhanced Collision Induced Unfolding and Electron Capture Dissociation of Native-like Protein Ions (2020, Analytical Chemistry)
  • Mass Spectrometry Methods for Measuring Protein Stability (2022, Chemical Reviews)
  • Bicelles Rich in both Sphingolipids and Cholesterol and Their Use in Studies of Membrane Proteins (2020, Journal of the American Chemical Society)
  • Mechanistic insights into accelerated α-synuclein aggregation mediated by human microbiome-associated functional amyloids (2022, Journal of Biological Chemistry)

Frequent collaborators include Varun V. Gadkari, Kristine F. Parson, Anna G. Anders, Robert T. Kennedy, and Carolina Rojas Ramírez, reflecting an active network of co-researchers linked to various studies.

The researcher's work is often published in established scientific venues with multiple publications in Analytical Chemistry, the Journal of the American Society for Mass Spectrometry, the Journal of Biological Chemistry, the Journal of the American Chemical Society, and bioRxiv (Cold Spring Harbor Laboratory).

Best Publications

  • Ion mobility-mass spectrometry analysis of large protein complexes.

    Brandon T. Ruotolo;Justin L.P. Benesch;Alan M. Sandercock;Suk Joon Hyung

  • Amyloid-β protein oligomerization and the importance of tetramers and dodecamers in the aetiology of Alzheimer's disease

    Summer L. Bernstein;Nicholas F. Dupuis;Noel D. Lazo;Thomas Wyttenbach

  • Collision Cross Sections of Proteins and Their Complexes: A Calibration Framework and Database for Gas-Phase Structural Biology

    Matthew F. Bush;Zoe Hall;Kevin Giles;John Hoyes

  • Evidence for macromolecular protein rings in the absence of bulk water.

    Brandon T. Ruotolo;Kevin Giles;Iain Campuzano;Alan M. Sandercock

  • Protein complexes in the gas phase: technology for structural genomics and proteomics.

    Justin L. P. Benesch;Brandon T. Ruotolo;Douglas A. Simmons;Carol V. Robinson

  • Ion mobility–mass spectrometry: a new paradigm for proteomics

    John A. McLean;Brandon T. Ruotolo;Kent J. Gillig;David H. Russell

  • Mass spectrometry: come of age for structural and dynamical biology

    Justin L P Benesch;Brandon T Ruotolo

  • Aspects of native proteins are retained in vacuum.

    Brandon T Ruotolo;Carol V Robinson

  • Ion mobility-mass spectrometry reveals long-lived, unfolded intermediates in the dissociation of protein complexes.

    Brandon T. Ruotolo;Suk Joon Hyung;Paula M. Robinson;Kevin Giles

  • Insights into antiamyloidogenic properties of the green tea extract (−)-epigallocatechin-3-gallate toward metal-associated amyloid-β species

    Suk Joon Hyung;Alaina S. Detoma;Jeffrey R. Brender;Sanghyun Lee

  • Tandem mass spectrometry reveals the quaternary organization of macromolecular assemblies.

    Justin L.P. Benesch;J. Andrew Aquilina;Brandon T. Ruotolo;Frank Sobott

  • Coupling microdroplet microreactors with mass spectrometry: reading the contents of single droplets online.

    Luis M Fidalgo;Graeme Whyte;Brandon T Ruotolo;Justin L P Benesch

  • Collision induced unfolding of isolated proteins in the gas phase: past, present, and future.

    Sugyan M Dixit;Daniel A Polasky;Brandon T Ruotolo

  • Structural basis for the inhibition of activin signalling by follistatin

    Adrian E. Harrington;Samantha A. Morris-Triggs;Brandon T. Ruotolo;Carol V. Robinson

  • Gas-Phase Unfolding and Disassembly Reveals Stability Differences in Ligand-Bound Multiprotein Complexes

    Suk Joon Hyung;Carol V. Robinson;Brandon T. Ruotolo

  • Ion mobility-mass spectrometry for structural proteomics.

    Yueyang Zhong;Suk Joon Hyung;Brandon T. Ruotolo

  • Mass measurements of increased accuracy resolve heterogeneous populations of intact ribosomes.

    Adam R. McKay;Brandon T. Ruotolo;Leopold L. Ilag;Carol V. Robinson

  • Coupling High-Pressure MALDI with Ion Mobility/Orthogonal Time-of-Flight Mass Spectrometry

    Kent J. Gillig;Brandon Ruotolo;Earle G. Stone;David H. Russell

  • Collision Induced Unfolding of Intact Antibodies: Rapid Characterization of Disulfide Bonding Patterns, Glycosylation, and Structures.

    Yuwei Tian;Linjie Han;Adam C. Buckner;Brandon T. Ruotolo

  • Alternate Dissociation Pathways Identified in Charge-Reduced Protein Complex Ions

    Kevin Pagel;Suk Joon Hyung;Brandon T. Ruotolo;Carol V. Robinson

Frequent Co-Authors

Carol V. Robinson
Carol V. Robinson University of Oxford
David H. Russell
David H. Russell Texas A&M University
Mi Hee Lim
Mi Hee Lim Korea Advanced Institute of Science and Technology
Ayyalusamy Ramamoorthy
Ayyalusamy Ramamoorthy Florida State University
Justin L. P. Benesch
Justin L. P. Benesch University of Oxford
James C. A. Bardwell
James C. A. Bardwell University of Michigan–Ann Arbor
E. Neil G. Marsh
E. Neil G. Marsh University of Michigan–Ann Arbor
John A. McLean
John A. McLean Vanderbilt University
Jeffrey R. Brender
Jeffrey R. Brender National Institutes of Health
Steven P. Schwendeman
Steven P. Schwendeman University of Michigan–Ann Arbor

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