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Immunology

D-Index
82
Citations
23961
World Ranking
1505
National Ranking
58

Overview

Takashi Yamamura is affiliated with the National Center of Neurology and Psychiatry in Japan. Their research primarily focuses on topics within Medicine and Immunology and Microbiology, contributing extensively to subfields such as Immunology, Pathology and Forensic Medicine, Neurology, Molecular Biology, and Rheumatology.

Their scientific work covers several main topics including Multiple Sclerosis Research Studies, Peripheral Neuropathies and Disorders, T-cell and B-cell Immunology, Immunotherapy and Immune Responses, Gut Microbiota and Health, Neuroinflammation and Neurodegeneration Mechanisms, and Fibromyalgia and Chronic Fatigue Syndrome Research.

Yamamura has published numerous papers, with recent notable publications including:

  • Safety and efficacy of satralizumab monotherapy in neuromyelitis optica spectrum disorder: a randomised, double-blind, multicentre, placebo-controlled phase 3 trial (2020, The Lancet Neurology)
  • Interleukin-6 in neuromyelitis optica spectrum disorder pathophysiology (2020, Neurology Neuroimmunology & Neuroinflammation)
  • Alterations of the gut ecological and functional microenvironment in different stages of multiple sclerosis (2020, Proceedings of the National Academy of Sciences)
  • Involvement of cytotoxic Eomes-expressing CD4 + T cells in secondary progressive multiple sclerosis (2021, Proceedings of the National Academy of Sciences)
  • Long-term Efficacy of Satralizumab in AQP4-IgG-Seropositive Neuromyelitis Optica Spectrum Disorder From SAkuraSky and SAkuraStar (2022, Neurology Neuroimmunology & Neuroinflammation)

Their frequent co-authors include Wakiro Sato, Youwei Lin, Tomoko Okamoto, Brian G. Weinshenker, and Daiki Takewaki.

The venues where Yamamura has published repeatedly encompass:

  • Neurology
  • Neurology Neuroimmunology & Neuroinflammation
  • Multiple Sclerosis and Related Disorders
  • Annals of Neurology
  • Clinical and Experimental Neuroimmunology

Best Publications

  • A synthetic glycolipid prevents autoimmune encephalomyelitis by inducing TH2 bias of natural killer T cells.

    Katsuichi Miyamoto;Sachiko Miyake;Takashi Yamamura

  • Functionally Distinct Subsets of CD1d-restricted Natural Killer T Cells Revealed by CD1d Tetramer Staining

    Jenny E. Gumperz;Sachiko Miyake;Takashi Yamamura;Michael B. Brenner

  • Dysbiosis in the gut microbiota of patients with multiple sclerosis, with a striking depletion of species belonging to clostridia XIVa and IV clusters

    Sachiko Miyake;Sangwan Kim;Wataru Suda;Kenshiro Oshima

  • Thyrotrophin in the pars tuberalis triggers photoperiodic response

    Nobuhiro Nakao;Hiroko Ono;Takashi Yamamura;Tsubasa Anraku

  • Interleukin 6 signaling promotes anti-aquaporin 4 autoantibody production from plasmablasts in neuromyelitis optica

    Norio Chihara;Toshimasa Aranami;Wakiro Sato;Yusei Miyazaki

  • Trial of Satralizumab in Neuromyelitis Optica Spectrum Disorder

    Takashi Yamamura;Ingo Kleiter;Kazuo Fujihara;Jacqueline Palace

  • Safety and efficacy of satralizumab monotherapy in neuromyelitis optica spectrum disorder: a randomised, double-blind, multicentre, placebo-controlled phase 3 trial

    Anthony Traboulsee;Benjamin M Greenberg;Jeffrey L Bennett;Lech Szczechowski

  • Direct suppression of CNS autoimmune inflammation via the cannabinoid receptor CB1 on neurons and CB2 on autoreactive T cells.

    Katarzyna Maresz;Gareth Pryce;Gareth Pryce;Eugene D Ponomarev;Giovanni Marsicano

  • Modulation of CD1d-restricted NKT cell responses by using N-acyl variants of α-galactosylceramides

    Karl O. A. Yu;Jin S. Im;Alberto Molano;Yves Dutronc

  • Regulation of Experimental Autoimmune Encephalomyelitis by Natural Killer (NK) Cells

    Unknown

  • Efficacy of the anti–IL-6 receptor antibody tocilizumab in neuromyelitis optica A pilot study

    Manabu Araki;Takako Matsuoka;Katsuichi Miyamoto;Susumu Kusunoki

  • Differential expression of NK T cell V alpha 24J alpha Q invariant TCR chain in the lesions of multiple sclerosis and chronic inflammatory demyelinating polyneuropathy.

    Zsolt Illés;Takayuki Kondo;Jia Newcombe;Nobuyuki Oka

  • Cannabinoids and the immune system : Potential for the treatment of inflammatory diseases?

    J. Ludovic Croxford;Takashi Yamamura

  • NKT cell-dependent amelioration of a mouse model of multiple sclerosis by altering gut flora.

    Hiroaki Yokote;Sachiko Miyake;J. Ludovic Croxford;Shinji Oki

  • Th17 Cells and Autoimmune Encephalomyelitis (EAE/MS)

    Toshimasa Aranami;Takashi Yamamura

  • The clinical implication and molecular mechanism of preferential IL-4 production by modified glycolipid-stimulated NKT cells

    Shinji Oki;Asako Chiba;Takashi Yamamura;Sachiko Miyake

  • Interleukin 6 Receptor Blockade in Patients With Neuromyelitis Optica Nonresponsive to Anti-CD20 Therapy

    Ilya Ayzenberg;Ingo Kleiter;Alexandra Schröder;Kerstin Hellwig

  • Invariant V(alpha)19i T cells regulate autoimmune inflammation.

    J Ludovic Croxford;Sachiko Miyake;Yi-Ying Huang;Michio Shimamura

  • Natural killer T cells accelerate atherogenesis in mice.

    Yukihito Nakai;Kazuya Iwabuchi;Satoshi Fujii;Naoki Ishimori

  • Cross-regulation between type I and type II NKT cells in regulating tumor immunity: a new immunoregulatory axis.

    Elena Ambrosino;Masaki Terabe;Ramesh C. Halder;Judy Peng

  • Suppression of collagen-induced arthritis by natural killer T cell activation with OCH, a sphingosine-truncated analog of α-galactosylceramide

    Asako Chiba;Shinji Oki;Katsuichi Miyamoto;Hiroshi Hashimoto

  • Mucosal-associated invariant T cells regulate Th1 response in multiple sclerosis.

    Yusei Miyazaki;Sachiko Miyake;Asako Chiba;Olivier Lantz

Frequent Co-Authors

Sachiko Miyake
Sachiko Miyake Juntendo University
Takeshi Tabira
Takeshi Tabira Juntendo University
Jun-ichi Satoh
Jun-ichi Satoh Meiji Pharmaceutical University
Noriko Sato
Noriko Sato Tokyo Medical and Dental University
Kazuo Fujihara
Kazuo Fujihara Fukushima Medical University
Jun-ichi Kira
Jun-ichi Kira Kyushu University
Albert Saiz
Albert Saiz Clínic Barcelona
David Baker
David Baker University of Washington
Gareth Pryce
Gareth Pryce Queen Mary University of London

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