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Sachiko Miyake

Sachiko Miyake

D-Index & Metrics

Immunology

D-Index
68
Citations
15515
World Ranking
2603
National Ranking
101

Overview

Sachiko Miyake is affiliated with Juntendo University in Japan. Their research primarily spans the fields of Medicine and Immunology and Microbiology, with a notable focus on Immunology, Molecular Biology, Neurology, Infectious Diseases, and Rheumatology as subfields of study.

The main topics of their work include immune cell function and interaction, T-cell and B-cell immunology, IL-33, ST2, and ILC pathways, multiple sclerosis research studies, neuroinflammation and neurodegeneration mechanisms, asthma and respiratory diseases, and gut microbiota and health.

Frequent publication venues for Miyake's work include the Juntendo Medical Journal, Frontiers in Immunology, Scientific Reports, Biomolecules, and Lara D. Veeken.

Their notable recent papers include:

  • Alterations of the gut ecological and functional microenvironment in different stages of multiple sclerosis, 2020, Proceedings of the National Academy of Sciences
  • Gasdermin D-mediated release of IL-33 from senescent hepatic stellate cells promotes obesity-associated hepatocellular carcinoma, 2022, Science Immunology
  • Gut dysbiosis and multiple sclerosis, 2020, Clinical Immunology
  • Inhibition of mTOR suppresses IFNα production and the STING pathway in monocytes from systemic lupus erythematosus patients, 2020, Lara D. Veeken
  • Reconstitution of Circulating Mucosal-Associated Invariant T Cells after Allogeneic Hematopoietic Cell Transplantation: Its Association with the Riboflavin Synthetic Pathway of Gut Microbiota in Cord Blood Transplant Recipients, 2020, The Journal of Immunology

Miyake has collaborated frequently with several co-authors, including Asako Chiba, Kazuhisa Takahashi, Goh Murayama, Isao Nagaoka, and Yuko Fujio.

Best Publications

  • A synthetic glycolipid prevents autoimmune encephalomyelitis by inducing TH2 bias of natural killer T cells.

    Katsuichi Miyamoto;Sachiko Miyake;Takashi Yamamura

  • Functionally Distinct Subsets of CD1d-restricted Natural Killer T Cells Revealed by CD1d Tetramer Staining

    Jenny E. Gumperz;Sachiko Miyake;Takashi Yamamura;Michael B. Brenner

  • Dysbiosis in the gut microbiota of patients with multiple sclerosis, with a striking depletion of species belonging to clostridia XIVa and IV clusters

    Sachiko Miyake;Sangwan Kim;Wataru Suda;Kenshiro Oshima

  • Interleukin 6 signaling promotes anti-aquaporin 4 autoantibody production from plasmablasts in neuromyelitis optica

    Norio Chihara;Toshimasa Aranami;Wakiro Sato;Yusei Miyazaki

  • Modulation of CD1d-restricted NKT cell responses by using N-acyl variants of α-galactosylceramides

    Karl O. A. Yu;Jin S. Im;Alberto Molano;Yves Dutronc

  • Efficacy of the anti–IL-6 receptor antibody tocilizumab in neuromyelitis optica A pilot study

    Manabu Araki;Takako Matsuoka;Katsuichi Miyamoto;Susumu Kusunoki

  • NKT cell-dependent amelioration of a mouse model of multiple sclerosis by altering gut flora.

    Hiroaki Yokote;Sachiko Miyake;J. Ludovic Croxford;Shinji Oki

  • The clinical implication and molecular mechanism of preferential IL-4 production by modified glycolipid-stimulated NKT cells

    Shinji Oki;Asako Chiba;Takashi Yamamura;Sachiko Miyake

  • Invariant V(alpha)19i T cells regulate autoimmune inflammation.

    J Ludovic Croxford;Sachiko Miyake;Yi-Ying Huang;Michio Shimamura

  • Natural killer T cells accelerate atherogenesis in mice.

    Yukihito Nakai;Kazuya Iwabuchi;Satoshi Fujii;Naoki Ishimori

  • Cross-regulation between type I and type II NKT cells in regulating tumor immunity: a new immunoregulatory axis.

    Elena Ambrosino;Masaki Terabe;Ramesh C. Halder;Judy Peng

  • The dual role of short fatty acid chains in the pathogenesis of autoimmune disease models.

    Miho Mizuno;Daisuke Noto;Naoko Kaga;Asako Chiba

  • Suppression of collagen-induced arthritis by natural killer T cell activation with OCH, a sphingosine-truncated analog of α-galactosylceramide

    Asako Chiba;Shinji Oki;Katsuichi Miyamoto;Hiroshi Hashimoto

  • Tyrosine Phosphorylation of Cbl upon Epidermal Growth Factor (EGF) Stimulation and Its Association with EGF Receptor and Downstream Signaling Proteins

    Toru Fukazawa;Sachiko Miyake;Vimla Band;Hamid Band

  • Mucosal-associated invariant T cells regulate Th1 response in multiple sclerosis.

    Yusei Miyazaki;Sachiko Miyake;Asako Chiba;Olivier Lantz

  • Butyrate suppresses demyelination and enhances remyelination.

    Tong Chen;Daisuke Noto;Yasunobu Hoshino;Miho Mizuno

  • A Novel Phosphotyrosine-binding Domain in the N-terminal Transforming Region of Cbl Interacts Directly and Selectively with ZAP-70 in T Cells

    Lupher Ml;Reedquist Ka;Miyake S;Langdon Wy

  • p120cbl Is a Major Substrate of Tyrosine Phosphorylation upon B Cell Antigen Receptor Stimulation and Interacts in Vivo with Fyn and Syk Tyrosine Kinases, Grb2 and Shc Adaptors, and the p85 Subunit of Phosphatidylinositol 3-Kinase

    Govindaswamy Panchamoorthy;Toru Fukazawa;Sachiko Miyake;Stephen Soltoff

  • Th2 bias of CD4+ NKT cells derived from multiple sclerosis in remission

    Manabu Araki;Takayuki Kondo;Jenny E. Gumperz;Michael B. Brenner

  • The regulatory role of natural killer cells in multiple sclerosis

    Kazuya Takahashi;Toshimasa Aranami;Masumi Endoh;Sachiko Miyake

  • Microarray analysis identifies an aberrant expression of apoptosis and DNA damage-regulatory genes in multiple sclerosis

    Jun-ichi Satoh;Megumi Nakanishi;Fumiko Koike;Sachiko Miyake

  • Costimulation-Dependent Modulation of Experimental Autoimmune Encephalomyelitis by Ligand Stimulation of Vα14 NK T Cells

    Endre Pál;Takeshi Tabira;Tetsu Kawano;Masaru Taniguchi

Frequent Co-Authors

Takashi Yamamura
Takashi Yamamura National Center of Neurology and Psychiatry
Ko Okumura
Ko Okumura Juntendo University
Yoshinari Takasaki
Yoshinari Takasaki Juntendo University
Hisaya Akiba
Hisaya Akiba Juntendo University
Sammy Bedoui
Sammy Bedoui University of Melbourne
Masaki Terabe
Masaki Terabe National Institutes of Health
Hideo Yagita
Hideo Yagita Juntendo University
Luc Van Kaer
Luc Van Kaer Vanderbilt University Medical Center
Jun-ichi Satoh
Jun-ichi Satoh Meiji Pharmaceutical University

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Related Online Degrees & Career Pathways

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Overall, combining an immunology background with nursing credentials prepares students for diverse and rewarding career pathways within healthcare, research, and patient education.

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