2026 Jenny E. Gumperz: Immunology Researcher – H-Index, Publications & Awards

Discipline name	D-Index	World Ranking	Current World Ranking	National Ranking	Current National Ranking	Publications	Citations
Immunology	55	3791	3494	1738	1589	112	12699

Overview

Jenny E. Gumperz is affiliated with the University of Wisconsin-Madison in the United States. Their research primarily focuses on immunology and microbiology, with significant contributions to related fields such as medicine, oncology, hematology, pathology, forensic medicine, and epidemiology. The scientist's work is often centered on immune cell function and interaction, especially in relation to T-cell and B-cell immunology, hematopoietic stem cell transplantation, and viral-associated cancers and disorders.

The research topics addressed by Jenny E. Gumperz include:

Immune Cell Function and Interaction
T-cell and B-cell Immunology
Hematopoietic Stem Cell Transplantation
Viral-associated cancers and disorders
CAR-T cell therapy research
Lymphoma Diagnosis and Treatment
Immunotherapy and Immune Responses

Jenny E. Gumperz has published extensively in several key academic journals. Frequent venues for their work include:

The Journal of Immunology
Regular and Young Investigator Award Abstracts
Neuro-Oncology
Science Advances
PLoS Pathogens

Their recent papers illustrate a focus on immunological mechanisms and viral effects on immune cells. Selected publications include:

"B cells infected with Type 2 Epstein-Barr virus (EBV) have increased NFATc1/NFATc2 activity and enhanced lytic gene expression in comparison to Type 1 EBV infection" (2020, PLoS Pathogens)
"Early T Cell Activation Metrics Predict Graft-versus-Host Disease in a Humanized Mouse Model of Hematopoietic Stem Cell Transplantation" (2020, The Journal of Immunology)
"Different Human Immune Lineage Compositions Are Generated in Non-Conditioned NBSGW Mice Depending on HSPC Source" (2020, Frontiers in Immunology)
"Inflammatory CD4/CD8 double-positive human T cells arise from reactive CD8 T cells and are sufficient to mediate GVHD pathology" (2023, Science Advances)
"Reduced IRF4 expression promotes lytic phenotype in Type 2 EBV-infected B cells" (2022, PLoS Pathogens)

Jenny E. Gumperz has collaborated frequently with several researchers, highlighting interdisciplinary connections within immunology and related areas. Frequent coauthors include:

Dana C. Baiu
Nicholas J Hess
Shannon C. Kenney
Amy W. Hudson
Peiman Hematti

The breadth of Jenny E. Gumperz's publications covers both fundamental immunological processes and applied medical research, often investigating immune cell behavior during viral infections and stem cell transplantation. Their contributions span a variety of roles in immunology, oncology, and hematology, indicating a multidisciplinary approach within the biomedical sciences.

Best Publications

Functionally Distinct Subsets of CD1d-restricted Natural Killer T Cells Revealed by CD1d Tetramer Staining

Jenny E. Gumperz;Sachiko Miyake;Takashi Yamamura;Michael B. Brenner

942
Citations
Mechanism of CD1d-restricted natural killer T cell activation during microbial infection

Manfred Brigl;Lynn Bry;Sally C Kent;Jenny E Gumperz

825
Citations
The Bw4 public epitope of HLA-B molecules confers reactivity with natural killer cell clones that express NKB1, a putative HLA receptor

Jenny E. Gumperz;Virginia Litwin;Joseph H. Phillips;Lewis L. Lanier

726
Citations
Murine CD1d-restricted T cell recognition of cellular lipids

Jenny E. Gumperz;Christopher Roy;Anna Makowska;Deirdre Lum

593
Citations
Direct Binding and Functional Transfer of NK Cell Inhibitory Receptors Reveal Novel Patterns of HLA-C Allotype Recognition

Christine C. Winter;Jenny E. Gumperz;Peter Parham;Eric O. Long

529
Citations
NKB1: a natural killer cell receptor involved in the recognition of polymorphic HLA-B molecules.

Virginia Litwin;Jenny Gumperz;Peter Parham;Joseph H. Phillips

508
Citations
Apolipoprotein-mediated pathways of lipid antigen presentation

Peter van den Elzen;Salil Garg;Luis León;Manfred Brigl

462
Citations
Superantigen-dependent, cell-mediated cytotoxicity inhibited by MHC class I receptors on T lymphocytes

Joseph H. Phillips;Jenny E. Gumperz;Peter Parham;Lewis L. Lanier

443
Citations
The enigma of the natural killer cell

Jenny E. Gumperz;Peter Parham

321
Citations
A New Model of Epstein-Barr Virus Infection Reveals an Important Role for Early Lytic Viral Protein Expression in the Development of Lymphomas

Shi Dong Ma;Subramanya Hegde;Ken H. Young;Ruth Sullivan

311
Citations
CD1d-restricted NKT cells express a chemokine receptor profile indicative of Th1-type inflammatory homing cells.

Seddon Y. Thomas;Runhua Hou;Jonathan E. Boyson;Terry K. Means

280
Citations
CD94 and a novel associated protein (94AP) form a NK cell receptor involved in the recognition of HLA-A, HLA-B, and HLA-C allotypes.

Joseph H. Phillips;Chiwen Chang;Jeanine Mattson;Jenny E. Gumperz

279
Citations
CD1-dependent dendritic cell instruction.

Michael S. Vincent;David S. Leslie;Jenny E. Gumperz;Xiaowei Xiong

279
Citations
Recognition of lyso-phospholipids by human natural killer T lymphocytes.

Lisa M. Fox;Daryl G. Cox;Jennifer L. Lockridge;Xiaohua Wang

266
Citations
Specificity of HLA class I antigen recognition by human NK clones: evidence for clonal heterogeneity, protection by self and non-self alleles, and influence of the target cell type.

V Litwin;J Gumperz;P Parham;J H Phillips

265
Citations
Regulation of CD1d expression and function by a herpesvirus infection

David Jesse Sanchez;Jenny E. Gumperz;Don Ganem

238
Citations
Conserved and variable residues within the Bw4 motif of HLA-B make separable contributions to recognition by the NKB1 killer cell-inhibitory receptor.

J E Gumperz;L D Barber;N M Valiante;L Percival

228
Citations
Heterogeneous phenotypes of expression of the NKB1 natural killer cell class I receptor among individuals of different human histocompatibility leukocyte antigens types appear genetically regulated, but not linked to major histocompatibililty complex haplotype.

J E Gumperz;N M Valiante;P Parham;L L Lanier

223
Citations
Low HLA-C Expression at Cell Surfaces Correlates with Increased Turnover of Heavy Chain mRNA

Jane A. McCutcheon;Jenny Gumperz;Kelly D. Smith;Charles T. Lutz

204
Citations
Determination of Cellular Lipids Bound to Human CD1d Molecules

Daryl G Cox;Daryl G Cox;Lisa M Fox;Runying Tian;Wilfried Bardet

202
Citations
Th2 bias of CD4+ NKT cells derived from multiple sclerosis in remission

Manabu Araki;Takayuki Kondo;Jenny E. Gumperz;Michael B. Brenner

198
Citations

Frequent Co-Authors

Peter Parham Stanford University

Lewis L. Lanier University of California, San Francisco

Michael B. Brenner Harvard Medical School

Gurdyal S. Besra University of Birmingham

Shannon C. Kenney University of Wisconsin–Madison

Erin J. Adams University of Chicago

Joseph H. Phillips MSD (United States)

William H. Hildebrand University of Oklahoma Health Sciences Center

Samuel M. Behar University of Massachusetts Chan Medical School

William J. Burlingham University of Wisconsin–Madison

External Links

Personal website of Jenny E. Gumperz

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